top of page

Publications in 2016


A tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles

PNAS, 2016;113(48):13720-13725.

Yu G, Cook TR, Li Y, Yan X, Wu D, Shao L Shen J, Tang G, Huang F, Chen X, Stang PJ


Enzyme-free colorimetric determination of EV71 virus using a 3D-MnO2-PEG nanoflower and 4-MBA-MA-AgNPs

Nanoscale. 2016;8(36):16168-16171.

Chu C, Ge S, Zhang J, Lin H, Liu G, Chen X


Synergistic thermoradiotherapy based on PEGylated Cu3BiS3 ternary semiconductor nanorods with strong absorption in the second near-infrared window

Biomaterials. 2016;112:164-175. 

Li A, Li X, Yu X, Li W, Zhao R, An X, Cui D, Chen X, Li W.


Hierarchical Assembly of Bioactive Amphiphilic Molecule Pairs into Supramolecular Nanofibril Self-Supportive Scaffolds for Stem Cell Differentiation

J Am Chem Soc, 2016;138(45):15027-15034.

Wang Z, Zhang F, Wang Z, Fu X, Jin A, Yung BC, Fan J, Yang X, Niu G, Chen X


Reactive Oxygen Species Generating Systems Meeting Challenges of Photodynamic Cancer Therapy

Chem Soc Rev, 2016;45(23):6597-6626.

Zhou Z, Song J, Nie L, Chen X


Albumin-Binding Evans Blue Derivatives for Diagnostic Imaging and Production of Long-Acting Therapeutics

Bioconjug Chem, 2016;27(10):2239–2247

Jacobson O, Kiesewetter DO, Chen X


New Generation of Gold Nanoshell-Coated Esophageal Stent: Preparation and Biomedical Applications

ACS Appl Mater Interfaces, 2016;8 (41):27523–27529

Song J, Hu H, Wu K, Chen X


DCE-MRI-Derived Parameters in Evaluating Abraxane-Induced Early Vascular Response and the Effectiveness of Its Synergistic Interaction with Cisplatin

PLoS One. 2016;11(9):e0162601.

Sun X, Yang L, Yan X, Sun Y, Zhao D, Ji Y, Wang K, Chen X, Shen B


Pillar[5]arene-based amphiphilic supramolecular brush copolymers: fabrication, controllable self-assembly and application in self-imaging targeted drug delivery

Polymer Chem, 2016;7:6178-6188.

Yu G, Zhao R, Wu D, Zhang F, Shao L, Zhou J, Yang J, Tang G, Chen X, Huang F


Magneto-Plasmonic Janus Vesicles for Magnetic Field-Enhanced Photoacoustic and Magnetic Resonance Imaging of Tumor

Angew Chem Int Ed Engl, 2016;55(49):15297-15300.

Liu Y, Yang X, Huang Z, Huang P, Zhang Y, Deng L, Wang Z, Zhou Z, Liu Y, Kalish H, Khachab NM, Chen X, Nie Z


A Highly Efficient Approach to Copper-Mediated Radioiodination Approach using Using Aryl Boronic Acids

Chem Eur J, 2016;22(47):16783-16786.

Zhang P, Zhuang R, Guo Z, Su X, Chen X, Zhang X


CCCCC pentadentate chelates with planar Möbius aromaticity and unique properties.

Sci Adv, 2016 Aug 26;2(8):e1601031.

Zhu C, Yang C, Wang Y, Lin G, Yang Y, Wang X, Zhu J, Chen X, Lu X, Liu G, Xia H.


Overcoming the Achilles’ heel of photodynamic therapy

Chem Soc Rev, 2016;45(23):6488-6519.

Fan W, Huang P, Chen X


Size dependent kinetics of gold nanorods in EPR mediated tumor delivery

Theranostics, 2016; 6(12): 2039-2051.

Tong X, Wang Z, Sun X, Song J, Jacobson O, Niu G, Kiesewetter DO, Chen X


Recent Advances in Photoacoustic Imaging for Deep-Tissue Biomedical Applications

Theranostics, 2016;6(13):2394-2413. 

Wang S, Lin J, Wang T, Chen X, Huang P


Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization

ACS Appl Mater Interfaces. 2016 Jun 8;8(22):13804-11.

Fan J, He Q, Liu Y, Zhang F, Yang X, Wang Z, Lu N, Fan W, Lin L, Niu G, He N, Song J, Chen X


Peptide-based imaging agents for cancer detection

Adv Drug Deliv Rev. 2016 Jun 18. pii: S0169-409X(16)30191-0.

Sun X, Li Y, Liu T, Li Z, Zhang X, Chen X


Temporal-spatially transformed synthesis and formation mechanism of gold bellflowers

Nanoscale, 2016 Apr 14;8(14):7430-4. (Front Cover)

Lin J, Zhang MG, Tang Y, Wen B, Hu H, Song J, Liu Y, Huang P, Chen X.


EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models

Oncotarget. 2016;7(34):54137-54156.

Venugopalan A, Lee MJ, Niu G, Medina-Echeverz J, Tomita Y, Lizak MJ, Cultraro CM, Simpson RM, Chen X, Trepel JB, Guha U


Efficient production and enhanced tumor delivery of engineered extracellular vesicles

Biomaterials. 2016 Jul 6;105:195-205.

Watson DC, Bayik D, Srivatsan A, Bergamaschi C, Valentin A, Niu G, Bear J, Monninger M, Sun M, Morales-Kastresana A, Jones JC, Felber BK, Chen X, Gursel I, Pavlakis GN


Gold Nanoparticle Coated Carbon Nanotube Ring with Enhanced Raman Scattering and Photothermal Conversion Property for Theranostic Applications

J Am Chem Soc, 2016 Jun 8;138(22):7005-15.

Song J, Wang F, Yang X, Huang P, Nie L, Lin L, Niu G, Chen J, Chen X


Graphene-Based Nanomaterials in Bioimaging

Adv Drug Deliv Rev, 2016;105(Pt B):242-254.

Huang P, Lin J, Chen X 


Self-assembly mechanisms of nanofibers from peptide amphiphiles in solution and on substrate surfaces

Nanoscale, 2016 Aug 4;8(31):14814-20.

Liao HS, Lin J, Liu Y, Gao Y, Horkay F, Huang P, Jin A, Chen X


Monitoring Tumor Hypoxia Using 18F-FMISO PET and Pharmacokinetics Modeling after Photodynamic Therapy

Sci Rep, 2016 Aug 22;6:31551.

Tong X, Srivatsan A, Jacobson O, Wang Y, Wang Z, Yang X, Niu G, Kiesewetter DO, Zheng H, Chen X


Hierarchical Targeting Strategy for Enhanced Tumor Tissue Accumulation/Retention and Cellular Internalization

Adv Mater, 2016 Sep;28(34):7340-64.

Wang S, Huang P, Chen X


A Photothermally Responsive Nanoprobe for Bioimaging Based on the Edman Degradation 

Nanoscale, 2016;8(20):10553-7.

Liu Y, Wang Z, Zhang H, Lang L, Ma Y, He Q, Lu N, Huang P, Liu Y, Gao S, Ma Q, Kiesewetter DO, Chen X


Ultrasensitive Fluorescence Immunoassay for the Detection of Ochratoxin A Using Catalase-Mediated Fluorescence Quenching of CdTe QDs

Nanoscale, 2016 Apr 28;8(17):9390-7.

Huang X, Zhan S, Xu H, Meng X, Xiong Y, Chen X


Preparation of Plasmonic Vesicles from Amphiphilic Gold Nanocrystals Grafted with Polymer Brushes

Nat Protoc, 2016;11(11):2287-2299.

Song J, Huang P, Chen X


Potential Applications of Using 68Ga-Evans Blue PET/CT in the Evaluation of Lymphatic Disorder

Clin Nucl Med, 2016;41:302-308. 

Zhang W, Wu P, Li F, Tong G, Chen X, Zhu Z


Biomineralization-Inspired Synthesis of Copper Sulfide-Ferritin Nanocages as Cancer Theranostics

ACS Nano, 2016;10(3):3453-60.

Wang Z, Huang P, Jacobson O, Wang Z, Liu Y, Lin L, Lin J, Lu N, Zhang H, Tian R, Niu G, Liu G, Chen X


Programmed Specific Targeting in Nanomedicine

ACS Nano, 2016;10(3):2991-4.

Wang S, Huang P, Chen X


Multimodal Imaging Guided Cancer Phototherapy by Versatile Biomimetic Theranostics with UV and γ Irradiation Protection

Adv Mater, 2016 May;28(17):3273-9.

Huang P, Wang M, Hu H, Yang X, Wen B, Wang Z, Song J, Zhang G, Niu G, Wang T, Huang P, Chen X


Photoacoustic molecular imaging: from multiscale biomedical applications towards early-stage theranostics

Trends Biotechnol, 2016;34:420-33.

Liu Y, Nie L, Chen X


DNA-inorganic hybrid nanovaccine for cancer immunotherapy

Nanoscale, 2016;8:6684-6692

Zhu G, Liu Y, Yang X, Kim Y-H, Zhang H, Jia R, Liao H-S, Jin A, Lin J, Aronova M, Leapman R, Nie Z, Niu G, Chen X


Simple bioconjugate chemistry serves great clinical advances: Albumin as a versatile platform for diagnosis and precision therapy

Chem Soc Rev, 2016;45(5):1432-56.

Liu Z, Chen X


Ultrahigh 19F Loaded Cu1.75S Nanoprobes for Simultaneous 19F Magnetic Resonance Imaging and Photothermal Therapy

ACS Nano, 2016;10(1):1355-62.

Chen H, Song M, Tang J, Hu G, Xu S, Guo Z, Li N, Cui J, Zhang X, Chen X, Wang L.


Artificial cells: from basic science to applications

Mater Today, 2016;19(9):516-532.

Xu C, Hu S, Chen X


[18F]NOTA-T140 Peptide for Noninvasive Visualization of CXCR4 Expression

Mol Imaging Biol, 2016;18(1):135-42.

Yan X, Niu G, Wang Z, Yang X, Kiesewetter DO, Jacobson O, Shen B, Chen X


Glucagon-like peptide-1 receptor PET/CT with 68Ga-NOTA-exendin 4 for the localization of insulinoma: a prospective cohort study

J Nucl Med, 2016 May;57(5):715-20.

Luo Y, Pan Q, Yao S, Zhang J, Yu M, Wu W, Xue H, Kiesewetter DO, Zhu Z, Li F, Zhao Y, Chen X


68Ga-NOTA-exendin-4 PET/CT in localization of an occult insulinoma and appearance of coexisting esophageal carcinoma

Clin Nucl Med, 2016;41:341-343

Luo Y, Li N, Kiesewetter DO, Chen X, Li F


A Stable Evans Blue Derived Exendin-4 peptide for Type 2 Diabetes Treatment

Bioconjug Chem, 2016;27(1):54-8.

Liu Y, Wang G, Zhang H, Ma Y, Lang L, Jacobson O, Kiesewetter DO, Zhu L, Gao S, Ma Q, Chen X


Dual-enhanced photothermal conversion property of reduced graphene oxide-coated gold superparticles for light-triggered acoustic and thermal theranostics

Nanoscale, 2016; 8: 2116-2122

Lin L, Yang X, Niu G, Song J, Yang H-H, Chen X


Chemical conjugation of Evans blue derivative: a strategy to develop long-acting therapeutics through albumin binding

Theranostics, 2016; 6(2):243-253.

Chen H, Wang G, Lang L, Jacobson O, Kiesewetter DO, Liu Y, Ma Y, Zhang X, Wu H, Zhu L, Niu G, Chen X


Effect of Surface Properties on Liposomal siRNA Delivery

Biomaterials, 2016;79:56-68.  

Xia Y, Tian J, Chen X


Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia

ACS Nano, 2016;10(1):633-47.

Song M, Liu T, Shi C, Zhang X, Chen X


In vivo Covalent Cross-linking of Photon-converted Rare-earth Nanostructures for Tumor Localization and Theranostics

Nat Comm, 2016;7:10432. 

Ai X, Ho CJH, Aw J, Attia ABE, Wang X, Wang Y, Chen H, Gao M, Chen X, Yeow EKL, Liu G, Olivio M, Xing B


Molecular Imaging Guided Delivery of RNAi Therapeutics for Cancer 

Adv Drug Deliv Rev, 2016 Sep 1;104:44-60.

Wang J, Mi P, Lin G, Wang Y, Liu G, Chen X


RGD PET: From Lesion Detection to Therapy Response Monitoring

J Nucl Med, 2016 Apr;57(4):501-2.

Niu G, Chen X


A nanoparticulate pre-chemosensitizer for efficacious chemotherapy of multidrug resistant breast cancer

Sci Rep, 2016;6:21459.

Guo S, Lv L, Shen Y, Hu Z, He Q, Chen X


In vivo MR and Fluorescence Dual-modality Imaging of Atherosclerosis Characteristics in Mice Using Profilin-1 Targeted Magnetic Nanoparticles

Theranostics, 2016; 6(2):272-286.

Wang Y, Su T, Chen J, Ma S, Zhang X, Li X, Chen Y, Cao L, Yang B, Liu G, Cao J, Chen X, Chen Y, Cao F


68Ga-NOTA-Aca-BBN(7-14) PET/CT in Healthy Volunteers and Glioma Patients 

J Nucl Med, 2016 Jan;57(1):9-14.

Zhang J, Li D, Lang L, Zhu Z, Wang L, Wu P, Niu G, Li F, Chen X


Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3

Theranostics, 2016; 6(1): 78-92

Chen H, Niu G, Wu H, Chen X

bottom of page