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Publications before 2016

505

Antibody-Drug Conjugates

Bioconjug Chem. 2015 Nov 18;26(11):2169. [Front Cover]

Peng L, Chen X

504

A novel self-assembled sandwich nanomedicine for NIR-responsive release of NO

Nanoscale. 2015;7(47):20055-62.

Fan J, He N, He Q, Liu Y, Ma Y, Fu X, Liu Y, Huang P, Chen X

503

Gold Nanoparticle Strings Wrap up into Plasmonic Vesicles for Enhanced Photoacoustic Imaging

Angew Chem Int Ed Engl, 2015;54:15809-12. (Back cover)

Liu Y, He J, Yang K, Yi C, Liu Y, Nie L, Khashab NM, Chen X, Nie Z

502

Photoacoustic and Colorimetric Visualization of Latent Fingerprints

ACS Nano, 2015 Dec 22;9(12):12344-8.

Song K, Huang P, Yi C, Ning B, Hu S, Nie L, Chen X, Nie Z

501

Improving Cell-Based Therapies by Nanomodification 

J Control Release, 2015;219:560-75.

Chen W, Fu L, Chen X

500

68Ga-NOTA-PRGD2 PET/CT for Integrin Imaging in Patients with Lung Cancer.

J Nucl Med, 2015;56(12):1823-7.

Zheng K, Liang N, Zhang J, Lang L, Zhang W, Li S, Zhao J, Li F, Zhu Z, Chen X

499

Virus-Mimetic Nanovesicles as a Versatile Antigen Delivery System

Proc Natl Acad Sci U S A, 2015; 112(45):E6129-38.

Zhang P, Chen Y, Zeng Y, Chu C, Tian R, Guo Z, Zheng Z, Li R, Sheng C, Wang Z, Li S, Ge S, Zhang X, Xia N, Liu G, Chen X

498

Noninvasive Dynamic Imaging of Tumor Microenvironment in Response to Nanoparticle-Mediated Photothermal Therapy

Theranostics, 2015; 5(12):1444-1455.

Zhang F, Cao J, Chen X, Yang K, Zhu L, Fu G, Huang X, Chen X

497

Penetrating the Blood Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles

ACS Nano, 2015;9(10):9470-4.

Ali IU, Chen X

496

Sequential Drug Release and Enhanced Photothermal Effect of Hybrid Reduced Graphene Oxide-Loaded Ultrasmall Gold Nanorod Vesicles for Cancer Therapy

ACS Nano, 2015; 9(9):9199-209.

Song J, Yang X, Jacobson O, Lin L, Huang P, Niu G, Ma Q, Chen X

495

NIR-responsive on-demand release of CO from metal carbonyl-caged graphene oxide nanomedicine

Adv Mater, 2015;27(42):6741-6. (Front Cover)

He Q, Kiesewetter DO, Fu X, Fan J, Huang P, Liu Y, Zhu G, Liu Y, Qian Z, Chen X

494

Tumor-specific formation of enzyme instructed supramolecular self-assemblies as cancer theranostics

ACS Nano, 2015;9(10):9517-27.

Huang P, Gao Y, Lin J, Hu H, Liao H-S, Yan X, Tang Y, Jin A, Song J, Niu G, Zhang G, Horkay F, Chen X

493

18F-labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression 

J Nucl Med, 2015;56(11):1780-5.

Jacobson O, Weiss ID, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu G, Kiesewetter DO, Vasdev, Liang SH, Chen X

492

Protein-Based Photothermal Theranostics for Imaging-Guided Cancer Therapy

Nanoscale, 2015;7(39):16330-6.

Rong P, Huang P, Liu Z, Lin J, Jin A, Ma Y, Niu G, Yu L, Zeng W, Wang W, Chen X

491

Clinical Translation of an Albumin-Binding PET Radiotracer 68Ga-NEB.

J Nucl Med, 2015; 56(10):1609-14.

Zhang J, Lang L, Li F, Zhu Z, Niu G, Chen X

490

Ortho-stabilized 18F-azido click agents and application in PET imaging of single-stranded DNA aptamer

Angew Chem Int Ed Engl, 2015; 54(43):12777-81.

Wang L, Jacobson O, Avdic D, Rotstein BH, Weiss ID, Collier L, Chen X, Vasdev N, Liang SH

489

Aptamer-drug conjugates.

Bioconjug Chem. 2015; 26(11):2186-97.

Zhu G, Niu G, Chen X

488

Boramino Acid as a Marker for Amino Acid Transporters

Sci Adv, 2015;1:e150069. [Highlighted by C&EN News]

Liu Z, Chen H, Chen K, Shao Y, Kiesewetter DO, Niu G, Chen X

487

Accelerating the Translation of Nanomaterials in Biomedicine.

ACS Nano. 2015;9(7):6644-54.

Mitragotri S, Anderson DG, Chen X, Chow EK, Ho D, Kabanov AV, Karp JM, Kataoka K, Mirkin CA, Petrosko SH, Shi J, Stevens MM, Sun S, Teoh S, Venkatraman SS, Xia Y, Wang S, Gu Z, Xu C.

486

Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy

Adv Mater, 2015;27(33):4910-7 (Front Cover). 

Song J, Yang X, Jacobson O, Huang P, Sun X, Lin L, Yan X, Niu G, Ma Q, Chen X

485

A Novel Method for Simultaneous Radiolabeling and Dimerizing Thiolated Peptides Using 18F-Hexafluorobenzene

Bioconjugate Chem, 2015; 26(10):2016-20. (Front Cover)

Jacobosn O, Yan X, Ma Y, Niu Gm Kiesewetter DO, Chen X

484

18F-Alfatide II PET/CT in healthy human volunteers and patients with brain metastases 

Eur J Nucl Med Mol Imaging, 2015; 42(13):2021-8.

Yu C, Pan D, Mi B, Xu Y, Lang L, Niu G, Yang M, Wan W, Chen X 

483

Development of Individualized Anti-Metastasis Strategies by Engineering Nanomedicines 

Chem Soc Rev, 2015; 44(17):6258-86.

He Q, Guo S, Qian Z, Chen X

482

Pilot Prospective Evaluation of 18F-Alfatide II for Detection of Skeletal Metastases 

Theranostics, 2015; 5(10):1115-1121.

Mi B, Yu C, Pan D, Yang M, Wan W, Niu G, Chen X

481

Gold Nanoparticles for In Vitro Diagnostics

Chem Rev, 2015; 115(19):10575-636

Zhou W, Gao X, Liu D, Chen X 

480

Plasmonic Vesicles of Amphiphilic Nanocrystals: Optically Active Multifunctional Platform for Cancer Diagnosis and Therapy

Acc Chem Res, 2015; 48(9):2506-15.

Song J, Huang P, Duan H, Chen X

479

One-step (18)F labeling of biomolecules using organotrifluoroborates

Nat Protoc, 2015;10(9):1423-32.

Liu Z, Lin K-S, Benard F, Pourghiasian M, Kiesewetter DO, Perrin DM, Chen X

478

Suspension array based on nanoparticle-encoded microspheres for high-throughput multiplexed detection

Chem Soc Rev, 2015;44(15):5552-95.

Leng Y, Sun K, Chen X, Li W 

477

Polymeric Nanovehicle Regulated Spatiotemporal Real-Time Imaging of the Differentiation Dynamics of Transplanted Neural Stem Cells after Traumatic Brain Injury 

ACS Nano, 2015;9(7):6683-95.

Wang Z, Zhang M, Wang L, Wang S, Kang F, Li G, Jacobson O, Niu G, Yang W, Wang J, Chen X.

476

Protein phosphatase 2A inhibition with LB100 enhances radiation-induced mitotic catastrophe and tumor growth delay in glioblastoma

Mol Cancer Ther. 2015;14(7):1540-7.

Gordon IK, Lu J, Graves CA, Huntoon K, Frerich JM, Hanson RH, Wang X, Hong CS, Ho W, Feldman MJ, Ikejiri B, Bisht K, Chen XS, Tandle A, Yang C, Arscott WT, Ye D, Heiss JD, Lonser R, Camphausen K, Zhuang Z

475

Co9 Se8 Nanoplates as a New Theranostic Platform for Photoacoustic/Magnetic Resonance Dual-Modal-Imaging-Guided Chemo-Photothermal Combination Therapy.

Adv Mater. 2015;27(21):3285-91.

Song XR, Wang X, Yu SX, Cao J, Li SH, Li J, Liu G, Yang HH, Chen X

474

Quantitative Evaluation of Tumor Early Response to a Vascular Disrupting Agent with Dynamic PET 

Mol Imaging Biol, 2015; 17(6):865-73.

Guo N, Zhang F, Zhang X, Guo J, Lang L, Kiesewetter DO, Niu G, Li Q, Chen X

473

Prospective Study of 68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and First Application in Glioma Patients

Theranostics, 2015; 5(8): 882-889.

Wang Z, Zhang M, Wang L, Wang S, Kang F, Li Q, Jacobson O, Niu G, Yang W, Wang J, Chen X

472

Lymphatic Imaging: Focus on Imaging Probes

Theranostics, 2015; 5(7): 686-697. 

Niu G, Chen X

471

Semimetal nanomaterials of antimony as highly efficient agent for photoacoustic imaging and photothermal therapy.

Biomaterials. 2015;45:18-26.

Li W, Rong P, Yang K, Huang P, Sun K, Chen X

470

Aptamer-Targeting Photoresponsive Drug Delivery System Using “Off-On” Graphene Oxide Wrapped Mesoporous Silica Nanoparticles

Nanoscale, 2015;7(14):6304-10.

Tang Y, Hu H, Zhang MG, Song J, Nie L, Wang S, Niu G, Huang P, Lu G, Chen X

469

Gold nanoparticles for photoacoustic imaging

Nanomedicine (Lond). 2015;10(2):299-320.

Li W, Chen X.

468

Kinetic Analysis of Dynamic 11C-acetate PET/CT Imaging as a Potential Method for Differentiation of Hepatocellular Carcinoma and Benign Liver Lesions

Theranostics, 2015; 5(4): 371-377.

Huo L, Guo J, Dang Y, Lv J, Zheng Y, Li F, Xie Q, Chen X

467

Quantitative Molecular Magnetic Resonance Imaging of Angiogenesis In Vivo using Polyvalent Cyclic RGD-Iron Oxide Microparticle Conjugates

Theranostics, 2015; 5(5):515-529.

Melemenidis S, Jefferson A, Ruparelia N, Akhtar AM, Xie J, Allen D, Hamilton A, Larkin JR, Perez-Balderas F, Smart SC, Muschel RJ, Chen X, Sibson NR, Choudhury RP

466

Molecular Imaging of Apoptosis: From Micro to Macro

Theranostics, 2015; 5(6):559-582.

Zeng W, Wang X, Xu P, Liu G, Eden HS, Chen X

465

Reversibly Extracellular pH Controlled Cellular Uptake and Photothermal Therapy by PEGylated Mixed-Charge Gold Nanostars

Small. 2015 Apr;11(15):1801-1810. (Inside front cover)

Wang S, Teng Z, Huang P, Liu D, Liu Y, Tian Y, Sun J, Li Y, Ju H, Chen X, Lu G

464

Optical and photoacoustic dual-modality imaging guided synergistic photodynamic/photothermal therapies

Nanoscale. 2015; 7(6):2520-6.

Yan X, Hu H, Lin J, Jin AJ, Niu G, Zhang S, Huang P, Shen B, Chen X

463

Nanoscintillator-Mediated X-ray Inducible Photodynamic Therapy for In Vivo Cancer Treatment.

Nano Lett. 2015; 15(4):2249-56.

Chen H, Wang GD, Chuang YJ, Zhen Z, Chen X, Biddinger P, Hao Z, Liu F, Shen B, Pan Z, Xie J.

462

Positron Emission Tomography Imaging Using Radiolabeled Inorganic Nanomaterials

Acc Chem Res, 2015;48(2):286-94.

Sun X, Cai W, Chen X

461

Design of a functional cyclic HSV1-TK reporter for PET imaging of apoptosis

Nat Protoc, 2015;10(5):807-21.

Wang Z, Wang F, Hida N, Kiesewetter DO, Tian J, Niu G, Chen X

460

Intrinsically Radioactive [64Cu]CuInS/ZnS Quantum Dots for PET and Optical Imaging: Improved Radiochemical Stability and Controllable Cerenkov Luminescence

ACS Nano, 2015; 9(1):488-95.

Guo W, Sun X, Jacobson O, Yan , Min K, Srivatsan A, Niu G, Kiesewetter DO, Chang J, Chen X

459

pH-Controlled Gas-Generating Mineralized Nanoparticles: A Theranostic Agent for Ultrasound Imaging and Therapy of Cancers

ACS Nano, 2015;9(1):134-45.

Min KH, Min HS, Lee HJ, Park DJ, Silvestre OF, Chen X, Yhee JY, Kim K, Kwon IC, Jeong SY, Hwang Y-S, Lee SC

458

Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes

Bioconjugate Chem, 2015; 26(1):1-18.

Jacobson O, Kiesewetter DO, Chen X

457

PEGylated Exendin-4, a modified GLP-1 analog exhibits longer-lasting cardioprotection than its unmodified parent molecule in a murine model of myocardial infarction

Theranostics, 2015; 5(3): 240-250.

Sun Z, Tong G, Kim TH, Ma N, Niu G, Cao F, Chen X

456

68Ga-NOTA-exendin-4 PET/CT in detection of occult insulinoma and evaluation of physiological uptake

Eur J Nucl Med Mol Imaging, 2015; 42(3):531-2. [Image of the month]

Luo Y, Yu M, Pan Q, Wu W, Zhang T, Kiesewetter DO, Zhu Z, Li F, Chen X, Zhao Y

455

Enhanced Fluorescence Imaging Guided Photodynamic Therapy of Sinoporphyrin Sodium Loaded Graphene Oxide

Biomaterials, 2015;42:94-102.

Yan X, Huang P, Niu G, Lin J, Jin AJ, Hu H, Zhang Y, Wu A, Lu J, Zhang S, Shen B, Chen X

454

PET Imaging of Tenascin-C with a Radiolabeled Single-Strand DNA Aptamer

J Nucl Med, 2015;56(4):616-21.

Jacobson O, Yan X, Niu G, Weiss ID, Ma Y, Szajek LP, Shen B, Kiesewetter DO, Chen X

453

In Vivo Albumin Labeling and Lymphatic Imaging

Proc Natl Acad Sci U S A, 2015;112:208-213

Wang Y, Lang L, Huang P, Wang Z, Jacobson O, Kiesewetter DO, Ali I, Teng G, Niu G, Chen X

452

Engineered Mesenchymal Stem Cells with Enhanced Tropism and Paracrine Secretion of Cytokines and Growth Factors to Treat Traumatic Brain Injury

Stem Cells, 2015; 33(2):456-67

Wang Z, Wang Y, Wang Z, Huang P, Wang Z, Patel V, Gutkind JS, Lu J, Niu G, Teng G, Chen X

451

Bioinspired Nanocomplex for Spatiotemporal Imaging of Sequential mRNA Expression in Differentiating Neural Stem Cells

ACS Nano, 2014; 8(12):12386-96. 

Wang Z, Zhang R, Wang Z, Wang HF, Wang Y, Zhao J, Wang F, Li W, Niu G, Kiesewetter DO, Chen X

450

Early-stage imaging of nanocarrier enhanced chemotherapy response in living subjects by scalable photoacoustic microscopy

ACS Nano, 2014; 8(12):12141-50.

Nie L, Huang P, Li W, Wang Z, Tang Y, Jin AJ, Wang S, Zhang F, Niu G, Chen X

449

Recent advances in nanoparticle-based nuclear imaging of cancers.

Adv Cancer Res. 2014;124:83-129.

Srivatsan A, Chen X. 

448

Mercaptopropionic acid-capped Mn2+:ZnSe/ZnO quantum dots with both downconversion and upconversion emissions for bioimaging applications.

Nanoscale. 2014 Oct 9;6(21):12345-9.

Zhao B, Yao Y, Yang K, Rong P, Huang P, Sun K, An X, Li Z, Chen X, Li W.

447

Attenuation of lung cancer stem cell tumorigenesis and metastasis by cisplatin

Exp Lung Res. 2014 Oct;40(8):404-14.

Wang S, Ma S, Li X, Xue Z, Zhang X, Fan W, Nie Y, Wu K, Chen X, Cao F.

446

A Novel 19F Activatable Probe for the Detection of Matrix Metalloprotease-2 Activity by MRI/MRS

Mol Pharm, 2014;11(11):4208-17.

Yue X, Wang Z, Zhu L, Wang Y, Qian C, Ma Y, Kiesewetter DO, Niu G, Chen X

445

PET and NIR Optical Imaging Using Self-Illuminating 64Cu-Doped Chelator-Free Gold Nanoclusters

Biomaterials, 2014 Dec;35(37):9868-76.

Hu H, Huang P, Weiss OJ, Yan X, Yue X, Zhang MG, Tang Y, Nie L, Ma Y, Niu G, Wu K, Chen X

444

In vivo quantitative photoacoustic microscopy of gold nanostar kinetics in mouse organs

Biomed Opt Express. 2014;5(8):2679-85.

Li W, Sun X, Wang Y, Niu G, Chen X, Qian Z, Nie L.

443

Dye Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy

Adv Mater, 2014 Oct;26(37):6401-8.

Huang P, Rong P, Jin A, Yan X, Zhang MG, Lin J, Hu H, Wang Z, Yue X, Li W, Niu G, Zeng W, Wang W, Zhou K, Chen X

442

Intraoperative Imaging-Guided Cancer Surgery: From Current Optical Molecular Imaging Methods to Future Multi-Modality Imaging Technology

Theranostics, 2014; 4(11):1072-1084.

Chi C, Du Y, Ye J, Kou D, Qiu J, Wang J, Tian J, Chen X

441

Quantitative proteomics analysis identifies mitochondria as therapeutic targets of multidrug-resistance in ovarian cancer

Theranostics, 2014; 4(12): 1164-1175.

Chen X, Wei S, Ma Y, Lu J, Niu G, Xue Y, Chen X, Yang F

440

Transient absorption microscopy of gold nanorods as spectrally orthogonal labels in live cells

Nanoscale. 2014 Sep 21;6(18):10536-9.

Chen T, Chen S, Zhou J, Liang D, Chen X, Huang Y.

439

The Interplay between Longitudinal and Transverse Contrasts in Fe3O4 Nanoplates with (111) Exposed Surfaces

ACS Nano. 2014 Aug 26;8(8):7976-85.

Zhou Z, Zhao Z, Zhang H, Wang Z, Chen X, Wang R, Chen Z, Gao J.

438

68Ga-PRGD2 PET/CT in the evaluation of glioma: a prospective study

Mol Pharm. 2014;11(11):3923-9.

Li D, Zhao X, Zhang L, Li F, Ji N, Gao Z, Wang J, Kang P, Liu Z, Shi J, Chen X, Zhu Z.

437

Role of Albumin in the Formation and Stabilization of Nanoparticle Aggregates in Serum Studied by Continuous Photon Correlation Spectroscopy and Multiscale Computer Simulations

J Phys Chem C 2014, 118, 16199-16208

Bhirde AA, Hassan SA, Harr E, Chen X

436

Chelator-Free 64Cu-Integrated Gold Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy.

ACS Nano. 2014 Aug 26;8(8):8438-46.

Sun X, Huang X, Yan X, Wang Y, Guo J, Jacobson O, Liu D, Szajek LP, Zhu W, Niu G, Kiesewetter DO, Sun S, Chen X.

435

Application of (68)Ga-PRGD2 PET/CT for αvβ3-integrin Imaging of Myocardial Infarction and Stroke.

Theranostics. 2014 May 25;4(8):778-86.

Sun Y, Zeng Y, Zhu Y, Feng F, Xu W, Wu C, Xing B, Zhang W, Wu P, Cui L, Wang R, Li F, Chen X, Zhu Z.

434

Structural and functional photoacoustic molecular tomography aided by emerging contrast agents. 

Chem Soc Rev. 2014 Sep 22;43(20):7132-70.

Nie L, Chen X. 

433

Photostimulable near-infrared persistent luminescent nanoprobes for ultrasensitive and longitudinal deep-tissue bio-imaging.

Theranostics. 2014 Aug 24;4(11):1112-22.

Chuang YJ, Zhen Z, Zhang F, Liu F, Mishra JP, Tang W, Chen H, Huang X, Wang L, Chen X, Xie J, Pan Z.

432

[18F]DPA-714 PET Imaging of AMD3100 Treatment in a Mouse Model of Stroke

Mol Pharm, 2014 Oct 6;11(10):3463-70.

Wang Y, Yue X, Kiesewetter DO, Lu J, Niu G, Teng G, Chen X

431

Color Tunable Gd-Zn-Cu-In-S/ZnS Quantum Dots for Dual Modality Magnetic Resonance and Fluorescence Imaging

Nano Res, 2014; 7(11):1581-1591.

Guo W, Yang W, Wang Y, Sun X, Liu Z, Zhang B, Chang J, Chen X

430

Surface Functionalization of Chemically Reduced Graphene Oxide for Targeted Photodynamic Therapy

J Biomed Nanotechnol, 2015;11:117-125

Huang P, Wang S, Wang X, Shen G, Lin J, Wang Z, Guo S, Cui D, Yang M, Chen X

429

Glucose Oxidase-Catalyzed Growth of Gold Nanoparticles Enables Quantitative Detection of Attomolar Cancer Biomarkers.

Anal Chem. 2014; 86(12):5800-6.

Liu D, Yang J, Wang HF, Wang Z, Huang X, Wang Z, Niu G, Hight Walker AR, Chen X.

428

Stability enhanced polyelectrolyte-coated gold nanorod-photosensitizer complexes for high/low power density photodynamic therapy.

Biomaterials. 2014 Aug;35(25):7058-67.

Shi Z, Ren W, Gong A, Zhao X, Zou Y, Brown EM, Chen X, Wu A.

427

Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics.

J Am Chem Soc. 2014 Jun 11;136(23):8307-13.

Huang P, Rong P, Lin J, Li W, Yan X, Zhang MG, Nie L, Niu G, Lu J, Wang W, Chen X.

426

Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles.

ACS Nano. 2014;8(6):6004-13.

Zhen Z, Tang W, Chuang YJ, Todd T, Zhang W, Lin X, Niu G, Liu G, Wang L, Pan Z, Chen X, Xie J.

425

One-Pot Two-Step Radiosynthesis of a New 18F-Labeled Thiol Reactive Prosthetic Group and Its Conjugate for Insulinoma Imaging

Mol Pharm, 2014;11(11):3875-84.

Yue X, Yan Y, Wu X, Niu G, Ma Y, Jacobson O, Shen B, Kiesewetter DO, Chen X

424

Multifunctional Fe3O4@Polydopamine Core-Shell Nanocomposites for Intracellular mRNA Detection and Imaging-Guided Photothermal Therapy

ACS Nano. 2014; 8(4):3876-83.

Lin LS, Cong ZX, Cao JB, Ke KM, Peng QL, Gao J, Yang HH, Liu G, Chen X.

423

A versatile RNAi nanoplatforms for systemic delivery of RNAis

ACS Nano, 2014; 8(5):4559-70.

Choi KY, Silvestre OF, Huang X, Howard GP, Hida N, Jin AJ, Carvajal N, Lee SW, Hong JI, Chen X. 

422

Facile Synthesis of Pentacle Au-Cu Alloy Nanocrystals and their Plasmonic and Catalytic Properties

Nat Comm, 2014 Jul 7;5:4327.

He R, Wang YC, Wang X, Wang Z, Liu G, Zhou W, Wen L, Li Q, Wang X, Chen X, Zeng J, Hou JG

421

Targeted Therapeutic Nanotubes Influence the Viscoelasticity of Cancer Cells to Overcome Drug Resistance

ACS Nano, 2014; 8(5):4177-89.  

Bhirde AA, Chikkaveeraiah BV, Srivatsan A, Niu G, Jin AJ, Kapoor A, Wang Z, Patel S, Patel V, Gorbach AM, Leapman RD, Gutkind JS, Hight Walker AR, Chen X

420

In Vivo Labeling of Serum Albumin for Positron Emission Tomography 

J Nucl Med, 2014;55(7):1150-6.

Niu G, Lang L, Kiesewetter DO, Sun Z, Guo N, Guo J, Wu C, Ma Y, Chen X

419

Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes

Nat Comm, 2014;5:5799. 

Yong R, Yang C, Lu J, Wang H, Schlaff C, Tandle A, Graves C, Elkahloun A, Chen X, Zhuang Z, Lonser R

418

Design Considerations of Iron-based Nanoclusters for Non-invasive Tracking of Mesenchymal Stem Cell Homing 

ACS Nano, 2014; 8(5):4403-14.

Huang X, Zhang F, Wang Y, Sun X, Choi KY, Liu D, Choi JS, Shin TH, Cheon J, Niu G, Chen X

417

A symmetrical fluorous dendron-cyanine dye conjugated bimodal nanoprobe for quantitative 19F MRI and NIR fluorescence bioimaging

Adv Healthcare Mater, 2014;3(8):1326-33.

Wang Z, Yue X, Wang Y, Qian C, Huang P, Lizak M, Niu G, Wang F, Rong P, Kiesewetter DO, Ma Y, Chen X

416

Carbon dots based two-photon visible nanocarriers for safe and highly efficient delivery of siRNA and DNA

Adv Healthc Mater. 2014; 3(8):1203-9. (back cover)

Wang L, Wang X, Bhirde A, Cao J, Zeng Y, Huang X, Sun Y, Liu G, Chen X

415

Stability analysis of glutamic acid linked peptides coupled to NOTA through different chemical linkages

Mol Pharm, 2014;11(11):3867-74.

Lang L, Ma Y, Kisewetter DO, Chen X

414

A Novel Cyclic HSV1-TK Reporter Probe for Real-Time Apoptosis Imaging 

Proc Natl Acad Sci U S A. 2014;111(14):5165-70.

Wang F, Hida N, Kiesewetter DO, Yang K, Wang Z, Rong P, Liang J, Tian J, Niu G, Chen X

413

Evaluation of synovial angiogenesis in patients with rheumatoid arthritis using 68Ga-PRGD2 PET/CT: a prospective proof-of-concept cohort study

Ann Rheum Dis 2014;73(6):1269-72

Zhu Z, Yin Y, Zheng K, Li F,Chen X, Zhang F, Zhang Y. 

412

Dual imaging-guided photothermal/photodynamic therapy using micelles

Biomaterials, 2014 May;35(16):4656-66.

Guo M, Mao H, Li Y, Zhu A, He H, Yang H, Wang Y, Tian X, Ge C, Peng Q, Wang X, Yang X, Chen X, Liu G, Chen H

411

Propranolol Inhibits Glucose Metabolism and 18F-FDG Uptake of Breast Cancer Through Posttranscriptional Downregulation of Hexokinase-2

J Nucl Med. 2014; 55(3):439-45.

Kang F, Ma W, Ma X, Shao Y, Yang W, Chen X, Li L, Wang J.

410

PET imaging of neuroinflammation in a rat traumatic brain injury model with radiolabeled TSPO ligand DPA-714

Eur J Nucl Med Mol Imaging, 2014; 41(7):1440-9.

Wang Y, Yue X, Kisewetter DO, Niu G, Teng G, Chen X

409

Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics

Chem Rev, 2014; 114(10):5161-214.

Chen G, Qiu H, Prasad PN, Chen X

408

A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo.

Nat Protoc, 2014;9(8):1900-15.

Choi KY, Huang X, Swierczewska M, Lee SW, Hong JI, Lee S, Chen X

407

Comparison of Three Dimeric 18F-AlF-NOTA-RGD Tracers

Mol Imaging Biol, 2014 Apr;16(2):274-83.

Guo J, Lang L, Hu S, Guo N, Zhu L, Sun Z, Ma Y, Kiesewetter DO, Niu G, Xie Q, Chen X

406

18F-Alfatide and 18F-FDG Dual Tracer Dynamic PET for Parametric, Early Prediction of Tumor Response to Therapy

J Nucl Med, 2014; 55(1):154-60.

Guo J, Guo N, Lang L, Kiesewetter DO, Xie Q, Li Q, Eden HS, Niu G, Chen X

405

Multimodality Imaging of Tumor Angiogenesis in Breast Cancer Experimental Lung Metastasis

Mol Pharm, 2012; 9 (8), 2339-49.

Hong H, Zhang Y, Severin GW, Yang Y, Engle JW, Niu G, Nathanson AJ, Chen X, Leigh BR, Barnhart TE, Cai W

404

The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development

Biomaterials, 2014;35(2):856-65.

Huang X, Zhang F, Sun X, Choi KY, Niu G, Zhang G, Guo J, Lee S, Chen X

403

Spatial Vascular Volume Fraction Imaging for Quantitative Assessment of Angiogenesis

Mol Imaging Biol, 2014; 16(3):362-71.

Liu J, Fan W, Liu M, Lin X, Wang Y, Wang F, Chen X, Cao F, Liang J

402

In vivo volumetric molecular photoacoustic angiography and therapeutic monitoring with targeted plasmonic nanostars

Small, 2014; 10(8):1585-93.  (Cover feature)

Nie L, Wang S, Wang X, Rong P, Ma Y, Liu G, Huang P, Lu G, Chen X

401

Palladium nanosheets as highly stable and effective contrast agents for in vivo photoacoustic molecular imaging

Nanoscale. 2014 Jan 16;6(3):1271-6. 

Nie L, Chen M, Sun X, Rong P, Zheng N, Chen X.

400

Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy

Theranostics, 2014; 4(3): 229-239.

Rong P, Yang K, Srivatsan A, Kiesewetter DO, Yue X, Wang F, Nie L, Bhirde A, Wang Z, Liu Z, Niu G, Wang W, Chen X

399

NIR-light-induced surface-enhanced Raman scattering for detection and photothermal/photodynamic therapy of cancer cells using methylene blue-embedded gold nanorod@SiO2 nanocomposites

Biomaterials. 2014; 35(10):3309-18.

Seo SH, Kim BM, Joe A, Han HW, Chen X, Cheng Z, Jang ES

398

Biomimetic RNA-Silencing Nanocomplexes: Overcoming Multidrug Resistance in Cancer Cells.

Angew Chem Int Ed Engl. 2014; 53(7):1997-2001. (Back Cover)

Wang Z, Wang Z, Liu D, Yan X, Wang F, Niu G, Yang M, Chen X

397

Self-Illuminating 64Cu-Doped CdSe/ZnS Nanocrystals for in Vivo Tumor Imaging

J Am Chem Soc. 2014;136(5):1706-9.

Sun X, Huang X, Guo J, Zhu W, Ding Y, Niu G, Wang A, Kiesewetter DO, Wang ZL, Sun S, Chen X

396

Rigid nanoparticle-based delivery of anti-cancer siRNA: challenges and opportunities

Biotechnol Adv, 2014;114(10):5161-214.

Wang Z, Liu G, Zheng H, Chen X

395

Polymeric Materials for Theranostic Applications

Pharm Res, 2014; 31(6):1358-76.

Wang Z, Niu G, Chen X

394

Visualization of protease activity in vivo using an activatable photo-acoustic imaging probe based on CuS nanoparticles 

Theranostics, 2014; 4(2):134-141.

Yang K, Zhu L, Nie L, Sun X, Cheng L, Niu G, Liu G, Chen X

393

Longitudinal PET imaging of muscular inflammation using 18F-DPA-714 and 18F-Alfatide II and differentiation with tumors

Theranostics, 2014;4(5):546-55. 

Wu C, Yue X, Lang L, Kiesewetter DO, Li F, Zhu Z, Niu G, Chen X

392

Rational Design of Matrix Metalloproteinase-13 Activatable Probes for Enhanced Specificity 

ACS Chem Biol, 2014; 9(2):510-6.

Zhu L, Ma Y, Kiesewetter DO, Wang Y, Lang L, Lee S, Niu G, Chen X

391

Application of 99mTechnetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) SPECT/CT in prostate cancer patients: A first-in-man study

Nucl Med Biol. 2013;40(7):933-8. 

Ananias HJ, Yu Z, Hoving HD, Rosati S, Dierckx RA, Wang F, Yan Y, Chen X, Pruim J, Lub-de Hooge MN, Helfrich W, Elsinga PH, de Jong IJ.

390

Non-Invasive Monitoring of Pulmonary Fibrosis by Targeting Matrix Metalloproteinases (MMPs) 

Mol Pharm, 2013 Jun 3;10(6):2237-47.

Cai Y, Zhu L, Zhang F, Niu G, Lee S, Kimura S, Chen X

389

Self-assembly of gold nanoparticles to silver microspheres as highly efficient 3D SERS substrates.

Nanoscale Res Lett, 2013;8(1):168. 

Chen S, Huang P, Wang Z, Wang Z, Swierczewska M, Niu G, Cui D, Chen X

388

Picomolar Detection of Mercuric Ions by Means of Gold-Silver Core-Shell Nanorod

Nanoscale, 2013; 5(15):6731-5.

Chen S, Liu D, Wang Z, Sun X, Cui D, Chen X

387

Targeted Delivery of siRNA-Generating DNA Nanocassettes Using Multifunctional Nanoparticles.

Small. 2013; 9(11):1964-73.

Cho YS, Lee GY, Sajja HK, Qian W, Cao Z, He W, Karna P, Chen X, Mao H, Wang YA, Yang L.

386

A Role for Phosphodiesterase 3B in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Male Mice

Endocrinology. 2013;154(9):3152-67.

Guirguis E, Hockman S, Chung YW, Ahmad F, Gavrilova O, Raghavachari N, Yang Y, Niu G, Chen X, Yu ZX, Liu S, Degerman E, Manganiello V

385

Self-assembly of amphiphilic plasmonic micelle-like nanoparticles in selective solvents

J Am Chem Soc, 2013;135(21):7974-84. doi: 10.1021/ja402015s

He J, Huang X, Li Y-C, Liu Y, Babu T, Aronova MA, Wang S, Lu Z, Chen X*, Nie Z*

384

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Nanomedicine (Lond). 2013;8(10):1571-2.

Ho D, Chen X

383

Photosensitizer-Conjugated Silica-Coated Gold Nanoclusters for Fluorescence Imaging-Guided Photodynamic Therapy 

Biomaterials, 2013;34(19):4643-54.

Huang P, Lin J, Wang S, Zhou Z, Li Z, Wang Z, Zhang C, Yue X, Niu G, Yang M, Cui D, Chen X

382

Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy 

Angew Chem Int Ed Engl, 2013; 52(52):13958-64. (Frontispiece)

Huang P, Lin J, Li W, Wang Z, Wang S, Wang X, Sun X, Aronova M Niu G, Leapman RD, Nie Z, Chen X

381

Mesenchymal stem cell-based cell engineering with multifunctional mesoporous silica nanoparticles for tumor delivery

Biomaterials. 2013 Feb;34(7):1772-80.

Huang X, Zhang F, Wang H, Niu G, Choi KY, Swierczewska M, Zhang G, Gao H, Wang Z, Zhu L, Choi HS, Lee S, Chen X.

380

The Effect of Injection Routes on the Biodistribution, Clearance and Tumor Uptake of Carbon Dots 

ACS Nano, 2013; 7(7):5684-93.

Huang X, Zhang F, Zhu L, Choi KY, Guo N, Guo J, Tackett K, Anilkumar P, Liu G, Quan Q, Choi HS, Niu G, Sun YP, Lee S, Chen X

379

Interrogating tumor metabolism and tumor micro-environments using molecular PET imaging. Theranostic approaches to improve therapeutics

Pharmacol Rev, 2013;65(4):1214-56. 

Jacobson O, Chen X

378

Nanotheranostics for personalized medicine.

Expert Rev Mol Diagn. 2013;13(3):257-69.

Kim TH, Lee S, Chen X

377

One-step and one-pot-two-step radiosynthesis of cyclo-RGD-(18)F-aryltrifluoroborate conjugates for functional imaging

Am J Nucl Med Mol Imaging. 2013;3(1):44-56.

Li Y, Guo J, Tang S, Lang L, Chen X, Perrin DM.

376

Photosensitizer-Loaded Gold Vesicles with Strong Plasmonic Coupling Effect for Imaging-Guided Photothermal/Photodynamic Therapy

ACS Nano, 2013;7(6):5320-9.

Lin J, Wang S, Huang P, Wang Z, Chen S, Niu G, Li W, He J, Cui D, Lu G, Chen X*, Nie Z*

375

Gold Nanoparticle-Based Activatable Probe for Sensing Ultralow Levels of Prostate-Specific Antigen.

ACS Nano. 2013;7(6):5568-76.

Liu D, Huang X, Wang Z, Jin A, Sun X, Zhu L, Wang F, Ma Y, Niu G, Hight Walker AR, Chen X

374

Acetylcholinesterase-catalyzed hydrolysis allows ultrasensitive detection of pathogens with the naked eye

Angew Chem Int Ed Engl, 2013; 52(52):14065-9. (back cover)

Liu D, Wang Z, Jin A, Huang X, Sun X, Wang F, Yan Q, Ge S. Xia N, Niu G, Liu G, HightWalker AR, Chen X

373

Applications and Potential Toxicity of Magnetic Iron Oxide Nanoparticles

Small, 2013;9(9-10):1533-45.

Liu G, Gao J, Ai H, Chen X

372

Efficient 18F labeling of cysteine-containing peptides and proteins using tetrazine-trans-cyclooctene ligation

Mol Imaging. 2013;12(2):121-8.

Liu S, Hassink M, Selvaraj R, Yap LP, Park R, Wang H, Chen X, Fox JM, Li Z, Conti PS

371

Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52.

Lu J, Frerich JM, Turtzo LC, Li S, Chiang J, Yang C, Wang X, Zhang C, Wu C, Sun Z, Niu G, Zhuang Z, Brady RO, Chen X

370

Longitudinal Bioluminescence Imaging of the Dynamics of Doxorubicin Induced Apoptosis

Theranostics, 2013;3(3):190-200. 

Niu G, Zhu L, Ho DN, Zhang F, Gao H, Quan Q, Hida N, Ozawa T, Liu G, Chen X

369

A ketogenic diet increases brown adipose tissue mitochondrial proteins and UCP1 levels in mice

IUBMB Life. 2013 Jan;65(1):58-66.

Srivastava S, Baxa U, Niu G, Chen X, L Veech R.

368

VEGF-loaded Graphene Oxide as Theranostics for Multi-Modality Imaging-Monitored Targeting Therapeutic Angiogenesis of Ischemic Muscle

Nanoscale, 2013;5(15):6857-66.

Sun Z, Huang P, Tong G, Lin J, Jin A, Rong P, Zhu L, Nie L, Niu G, Cao F, Chen X

367

Noninvasive Visualization of MicroRNA-16 in the Chemoresistance of Gastric Cancer Using a Dual Reporter Gene Imaging System.

PLoS One, 2013;8(4):e61792.

Wang F, Song X, Li X, Xin J, Wang S, Yang W, Wang J, Wu K, Chen X, Liang J, Tian J, Cao F

366

First Experience of [18F]AlF-NOTA-PRGD2 in Lung Cancer Patients Using A New Lyophilized Kit for Rapid Radiofluorination

J Nucl Med, 2013;54(5):691-8.

Wan W, Guo N, Pan D, Yu C, Weng Y, Luo S, Ding H, Xu Y, Wang L, Lang X, Xie Q, Yang M, Chen X

365

Single Continuous Wave Laser Induced Photodynamic/Plasmonic Photothermal Therapy Using Photosensitizer-Functionalized Gold Nanostars

Adv Mater, 2013;25(22):3055-61. (cover feature)

Wang S, Huang P, Nie L, Xing R, Liu D, Wang Z, Lin J, Chen S, Niu G, Lu G, Chen X

364

Near-infrared Emitting Quantum Dots Encoded Microbeads Through Membrane Emulsification Route For Multiplexed Immunoassays

Small, 2013; 9(19):3327-35. (back cover)

Wang X, Wang G, Li W, Zhao B, Xing B, Leng Y, Dou H, Sun K, Shen L, Yuan X, Li J, Sun K, Han J, Xiao H, Li Y, Huang P, Chen X 

363

Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery

Nanoscale, 2013;5(17):8098-104.

Wang X, Zhou Z, Wang Z, Xue Y, Zeng Y, Gao J, Zhu L, Zhang X, Liu G, Chen X

362

Dual-factor triggered fluorogenic nanoprobe for ultrahigh contrast and subdiffraction near infrared fluorescence imaging

Biomaterials, 2013;34(26):6194-201

Wang Z, Zhang X, Huang P, Zhao W, Liu D, Nie L, Yue X, Wang S, Ma Y, Kiesewetter DO, Niu G, Chen X

361

PET Imaging of Inflammation Biomarkers 

Theranostics, 2013; 3(7): 448-466.

Wu C, Li F, Niu G, Chen X

360

Hollow Iron Oxide Nanoparticles as Multidrug Resistant Drug Delivery and Imaging Vehicles

Nano Res, 2013;6(1):1-9. 

Xing R, Bhirde AA, Wang S, Sun X, Liu G, Hou Y, Chen X

359

Functional magnetic nanoparticles for non-viral gene delivery and MR imaging

Pharm Res, 2014; 31(6):1377-89.

Xing R, Liu G, Zhu J, Hou Y, Chen X

358

Development of a new thiol site-specific prosthetic group and its conjugation with [cys40]-exendin-4 for in vivo targeting of insulinomas

Bioconjuagte Chem, 2013;24(7):1191-200.

Yue X, Kiesewetter DO, Guo J, Sun Z, Zhang X, Zhu L, Niu G, Ma Y, Lang X, Chen X

357

Organic-High Ionic Strengthe Aqueous Solvent Systems for Spiral Counter-Curren Chromatography: Gaphic Optimization of Partition coefficient

J Liq Chromatogr Relat Technol. 2013;36(4):504-512.

Zeng Y, Liu G, Ma Y, Chen X, Ito Y

356

Differentiation of Reactive and Tumor Metastatic Lymph Nodes with Diffusion-weighted and SPIO Enhanced MRI

Mol Imaging Biol, 2013;15(1):40-7.

Zhang F, Zhu L, Huang X, Niu G, Chen X

355

pH-Sensitive Fluorescent Dyes: Are They Really pH-Sensitive in Cells?

Mol Pharm, 2013;10(5):1910-7.

Zhang XX, Wang Z, Yue X, Ma Y, Kiesewetter DO, Chen X

354

Comparison of 18F-labeled CXCR4 antagonist peptides for PET imaging of CXCR4 expression

Mol Imaging Biol, 2013; 15(6):758-67.

Zhang XX, Sun Z, Guo J, Wang Z, Wu C, Niu G, Ma Y, Kiesewetter DO, Chen X

353

Concave superparamagnetic iron oxide nanoparticles with ultrahigh transverse relaxivity 

Nat Comm, 2013 Aug 1;4:2266. doi: 10.1038/ncomms3266.

Zhao Z, Zhou Z, Bao J, Hu J, Chi X, Ni K, Chen X, Chen Z, Gao J

352

RGD-Modified Apoferritin Nanoparticles for Efficient Drug Delivery to Tumors 

ACS Nano, 2013;7(6):4830-7.

Zhen Z, Tang W, Chen H, Todd T, Wang J, Cowger T, Chen X, Xie J

351

Ferritin Nanocages To Encapsulate and Deliver Photosensitizers for Efficient Photodynamic Therapy against Cancer

ACS Nano, 2013;7(8):6988-96.

Zhen Z, Tang W, Guo C, Chen H, Lin X, Liu G, Fei B, Chen X, Xu B, Xie J.

350

Engineered Iron-Oxide-Based Nanoparticles as Enhanced T1 Contrast Agents for Efficient Tumor Imaging 

ACS Nano, 2013;7(4):3287-96.

Zhou Z, Wang L, Chi X, Bao J, Yang L, Zhao W, Chen Z, Wang X, Chen X, Gao J

349

Mitochondrial disulfide relay mediates translocation of p53 and partitions its subcellular activity

PNAS, 2013 Oct 22;110(43):17356-61.

Zhuang J, Wang P-Y, Huang X, Chen X, Kang J-G, Hwang PM

348

Nuclear mapping of nano-drug delivery systems in dynamic cellular environment

ACS Nano, 2012;6(6):4966-72.

Bhirde AA, Kapoor A, Iglesias-Bartolome R, Liu G, Jin A, Zhang G, Lee S, Leapman RD, Gutkind JS, Chen X

347

Assessment and comparison of magnetic nanoparticles as MRI contrast agents in a rodent model of human hepatocellular carcinoma 

Contrast Media Mol Imaging, 2012;7(4):363-72.

Bu L, Xie J, Chen K, Huang J, Aguilar ZP, Wang A, Sun KW, Chua M-S, SO M, Cheng Z, Shen B, Chen X 

346

Evaluation of 64Cu labeled GX1: A phage display peptide probe for PET imaging of tumor vasculature 

Mol Imaging Biol, 2012;14(1):96-105. 

Chen K, Sun X, Niu G, Ma Y, Yap L-P, Hui X, Wu K, Fan D, Chen X 

345

A Cy5.5-labeled phage-displayed peptide probe for near-infrared fluorescence imaging of tumor vasculature in living mice 

Amino Acids, 2012;41(4)1329-37. 

Chen K, Yap L-P, Park R, Hui X, Wu K, Fan D, Chen X , Conti PS 

344

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Theranostics. 2012;2(1):1-2. 

Chen X 

343

Electrochemical nanosensors for cancer protein biomarker detection

ACS Nano, 2012;6(8):6546-61.

Chikkaveeraiah BV, Bhirde A, Morgan N, Eden HS, Chen X

342

Initial Experience with Clinical-grade [18F]FPPRGD2: An Automated Multi-step Radiosynthesis for Human PET Studies 

Mol Imaging Biol, 2012;14(1):88-95. 

Chin FT, Shen B, Liu S, Berganos RA, Chang E, Mittra E, Chen X, Gambhir SS

341

Theranostic Nanoparticles Based on PEGylated Hyaluronic Acid: Early Diagnosis, Targeted Therapy and Therapeutic Monitoring of Colon Cancer

Biomaterials, 2012;33(26):6186-93

Choi KY, Jeon EJ, Yoon HY, Lee BS, Na JH, Min KH, Kim SY, Myung SJ, Lee S, Chen X, Kwon IC, Choi K, Jeong SY, Kim K, Park JH

340

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Nanoscale, 2012;4(2):330-42. 

Choi KY, Liu G, Lee S, Chen X

339

Protease-activated drug development

Theranostics 2012;2(2):156-79 (cover feature). 

Choi KY, Swierczewska M, Lee S, Chen X 

338

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ACS Nano 2012;6(6):4694-701.

de la Zerda A, Bodapati S, Teed R, May SY, Tabakman SM, Liu Z, Khuri-Yakub BT, Chen X, Dai H, Gambhir SS

337

PET Imaging of Glucagon-Like Peptide Receptor Upregulation after Myocardial Ischemia/Reperfusion Injury

J Nucl Med, 2012;53(12):1960-8.

Gao H, Kiesewetter DO, Zhang X, Huang X, Guo N, Lang L, Hida N, Wang H, Wang H, Cao F, Niu G, Chen X

336

PET Imaging of angiogenesis after myocardial infarction/reperfusion using a one-step labeled integrin-targeted tracer 18F-AlF-NOTA-PRGD2 

Eur J Nucl Med Mol Imaging. 2012;39(4):683-92.

Gao H, Lang L, Guo N, Cao F, Quan Q, Kiesewetter DO, Niu G, Chen X

335

In vivo USPIO magnetic resonance imaging shows that minocycline mitigates macrophage recruitment to a peripheral nerve injury

Mol Pain. 2012;8(1):49.

Ghanouni P, Behera D, Xie J, Chen X, Moseley M, Biswal S.

334

Quantitative analysis and parametric imaging of 18F-labeled monomeric and dimeric RGD peptides using compartment model

Mol Imaging Biol, 2012;14(6):743-52

Guo N, Lang L, Gao H, Niu G, Kiesewetter DO, Xie Q, Chen X

333

Quantitative analysis and comparison study of [18F]AlF-NOTA-PRGD2, [18F]FPPRGD2 and [68Ga]Ga-NOTA-PRGD2 Using a Reference Tissue Model

PLoS One, 2012;7(5):e37506. 

Guo N, Lang L, Li W, Gao H, Niu G, Kiesewetter DO, Xie Q, Chen X

332

Longitudinal PET imaging of doxorubicin induced cell death with 18F-Annexin V

Mol Imaging Biol, 2012;14(6):762-70.

Hu S, Kiesewetter DO, Zhu L, Guo N, Gao H, Liu G, Hilda N, Lang L, Niu G, Chen X 

331

Light-Triggered Theranostic Based on Photosensitizer-Conjugated Carbon Dots for Simultaneous Enhanced-Fluorescence Imaging and Photodynamic Therapy

Adv Mater, 2012;24(37):5104-10.

Huang P, Lin J, Wang X, Wang Z, Zhang C, Wang Q, He M, Li Z, Chen F, Shen G, Cui D, Chen X

330

Chiral Guanosine 5,-Monophosphate-Capped Gold Nanoflowers: Controllable Synthesis, Characterization, Surface-Enhanced Raman Scattering Activity, Cellular Imaging and Photothermal Therapy

Nano Res, 2012;5(9):630–639

Huang P, Pandoli O, Lin J, Wang Z, Zhang C, Han L, She S, Cui D, Chen X

329

Multiplex imaging of intracellular proteolytic cascade using a broad spectrum nano-quencher

Angew Chem Int Ed Engl, 2012;51(7):1625-30. 

Huang X, Swierczewska M, Choi KY, Zhu L, Bhirde A, Park J, Kim K, Xie J, Niu G, Lee S, Chen X

328

Long-term multimodal imaging of tumor draining sentinel lymph nodes using mesoporous silica-based nanoprobes 

Biomaterials, 2012;33(17):4370-8.

Huang X, Zhang F, Lee S, Swierczewska M, Kiesewetter DO, Lang L, Zhang G, Zhu L, Gao H, Choi HS, Niu G, Chen X

327

64Cu-NO2A-RGD-Glu-6-Ahx-BBN(7-14)Nh2: A multimeric targeting vector for positron-emission tomography imaging of prostate cancer

Nucl Med Biol, 2012;39(3):377-87. 

Jackson AB, Nanda PK, Rold TL, Sieckman GL, Szczodroski AF, Hoffman TJ, Chen X, Smith CJ

326

Improvement of CXCR4 tracer specificity for PET imaging 

J Control Release 2012:157(2):216-23. 

Jacobson O, Weiss ID, Szajek LP, Niu G, Ma Y, Kiesewetter DO, Peled A, Eden HS, Farber JM, Chen X 

325

The manipulation of natural killer cells to target tumor sites using magnetic nanoparticles

Biomaterials. 2012;33(22):5584-92.

Jang ES, Shin JH, Ren G, Park MJ, Cheng K, Chen X, Wu JC, Sunwoo JB, Cheng Z

324

Evaluation of an [18F]AlF-NOTA: Analog of Exendin-4 for Imaging of GLP-1 Receptor in Insulinoma

Theranostics 2012; 2(10):999-1009.

Kiesewetter DO, Guo N, Guo J, Gao H, Zhu L, Ma Y, Niu G, Chen X 

323

18F-radiolabeled analogs of exendin-4 for PET imaging of GLP-1 in insulinoma

Eur J Nucl Med Mol Imaging, 2012;39(3):463-73 

Kiesewetter DO, Gao H, Ma Y, Niu G, Quan Q, Guo N, Chen X

322

Site-Specific PEGylated Exendin-4 Modified with a High Molecular Weight Trimeric PEG Reduces Steric Hindrance and Increases Type 2 Anti-Diabetic Therapeutic Effects

Bioconjug Chem, 2012;23(11):2214-20

Kim TH, Jiang HH, Lim SM, Youn YS,Choi KY, Lee S, Chen X, Byun Y, Lee KC

321

PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting

J Control Release, 2012;162(2):422-428

Kim TH, Jo YG, Jiang HH, Lim SM, Youn YS, Lee S, Chen X, Lee KC

320

Comparison study of [18F]FAl-NOTA-PRGD2, [18F]FPPRDG2 and [68Ga]Ga-NOTA-PRGD2 for PET imaging of U87MG tumors in mice

Bioconjug Chem, 2012;22(12):2415-22. 

Lang L, Li W, Guo N, Ma Y, Kiesewetter DO, Niu G, Chen X

319

Evaluation of the angiogenesis inhibitor KR-31831 in SKOV-3 tumor-bearing mice using 64Cu-DOTA-VEGF121 and microPET 

Nucl Med Biol. 2012;39(6):840-6.

Lee I, Yoon KY, Kang CM, Lin X, Chen X, Kim JY, Kim SM, Ryu EK, Choe YS.

318

N-Succinimidyl 4-[18F]-fluoromethylbenzoate-labeled dimeric RGD peptide for imaging tumor integrin expression 

Amino Acids, 2012;43(3):1349-57.

Li W, Lang L, Niu G, Guo N, Ma Y, Kiesewetter DO, Shen B, Chen X

317

PET imaging of EGF receptors using [18F]FBEM-EGF in a head and neck squamous cell carcinoma model 

Eur J Nucl Med Mol Imaging, 2012;39(2):300-8. 

Li W, Niu G, Lang L, Guo N, Ma Y, Kiesewetter DO, Backer JM, Shen B, Chen X

316

Highly Robust, Recyclable Displacement Assay for Mercuric Ions in Aqueous Solutions and Living Cells

ACS Nano. 2012; 6(12):10999-1008.

Liu D, Wang S, Swierczewska M, Huang X, Bhirde AA, Sun J, Wang Z, Yang M, Jiang X, Chen X 

315

Sticky nanoparticles: a new platform for siRNA delivery by bis(Zinc(II)-dipicolyamine)-functionalized, self-assembled nanoconjugate 

Angew Chem Int Ed Engl, 2012;51(2):445-9. (Back Cover) 

Liu G, Choi K-Y, Bhirde A, Swierczewska M, Yin J, Lee SW, Park JH, Hong JI, Niu G, Lee S, Chen X

314

Design and fabrication of N-alkyl-polyethylenimine-stabilized iron oxide nanoclusters for gene delivery

Methods Enzymol. 2012;509:263-76.

Liu G, Wang Z, Lee S, Ai H, Chen X

313

Evaluation of fluorine-labeled gastrin-releasing peptide receptor (GRPR) agonists and antagonists by LC/MS 

Amino Acids, 2012;43(4):1625-32.

Ma Y, Yang M, Gao H, Niu G, Yan Y, Lang L, Kiesewetter DO, Chen X.

312

Usefulness of [18F]-DA and [18F]-DOPA for PET imaging in a mouse model of pheochromocytoma 

Nucl Med Biol, 2012;39(2):215-26. 

Martiniova L, Cleary S, Lai EW, Kiesewetter DO, Seidel J, Dawson L, Philips J, Thomasson D, Chen X, Eisenhofer G, Powers J, Kvetnansky R, Pacak K 

311

Biological characterizations of [Gd@C82(OH)22]n nanoparticles as fullerene derivatives for cancer therapy

Integr Biol (Camb). 2012;5(1):43-7.

Meng J, Liang X, Chen X, Zhao Y

310

Pharmacodynamics, Tissue Distribution, Toxicity Studies and Antitumor Efficacy of the Vascular Targeting Fusion Toxin VEGF121/rGel

Biochem Pharmacol, 2012;84(11):1534-40.

Mohamedali KA, Niu G, Luster TA, Thorpe PE, Gao H, Chen X, Rosenblum MG

309

Molecular imaging with activatable reporter systems

Theranostics. 2012;2(4):413-23. 

Niu G, Chen X

308

Molecular targeting of CEACAM6 using antibody probes of different sizes

J Control Release, 2012;161(1):18-24.

Niu G, Murad YM, Gao H, Hu S, Guo N, Jacobson O, Nguyen TD, Zhang J, Chen X

307

Separation of nucleobases and their derivatives with organic-high ionic strength aqueous phase systems by spiral high-speed counter-current chromatography 

J Chromatogr B Analyt Technol Biomed Life Sci, 2012;891-892:94-7.

Shibusawa Y, Yanagida A, Ogihara A, Ma Y, Chen X, Ito Y

306

Mitochondrial biogenesis and increased uncoupling protein 1 in brown adipose tissue of mice fed a ketone ester diet 

FASEB J, 2012;26(6):2351-62.

Srivastava S, Kashiwaya Y, King MT, Baxa U, Tam J, Niu G, Chen X, Clarke K, Veech RL.

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A Facile, One-Step Nanocarbon Functionalization for Biomedical Applications 

Nano Lett, 2012;12(7):3613-20.

Swierczewska M, Choi KY, Mertz EL, Huang X, Zhang F, Zhu L, Youn HY, Park JH, Bhirde A, Lee S, Chen X

304

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Chem Soc Rev, 2012;41(7):2641-55. 

Swierczewska M, Liu G, Lee S, Chen X

303

Visualization of copper metabolism with 64CuCl2 PET 

Mol Imaging Biol, 2012;14(1):14-6. 

Wang H, Chen X 

302

Site-specific Labeling of scVEGF with Fluorine-18 for Positron Emission Tomography Imaging 

Theranostics, 2012; 2(6): 607-17.

Wang H, Gao H, Guo N, Niu G, Ma Y, Kiesewetter DO, Chen X

301

A nanoscale graphene oxide-peptide biosensor for real-time specific biomarker detection on the cell surface

Chem Comm (Camb), 2012;48(78):9768-70.

Wang Z, Huang P, Bhirde A, Jin A, Ma Y, Niu G, Neamati N, Chen X

300

The chronic protective effects of limb remote preconditioning and the underlying mechanisms involved in inflammatory factors in rat stroke 

PLOS One, 2012;7(2):e30892. 

Wei D, Ren C, Chen X, Zhao H

299

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Mol Imaging Biol, 2012;14(1):106-14. 

Weiss ID, Jacobson O, Szajekc L, Kiesewetter DO, Chen X, Farber JM 

298

Polyaspartic acid coated manganese oxide nanoparticles for efficent liver MRI 

Nanoscale, 2011;3(12):4943-5. 

Xing R, Zhang F, Xie J, Aronova M, Zhang G, Guo N, Huang X, Sun X, Liu G, Liang A, Hou Y, Leapman RD, Sun S, Chen X

297

Imaging tumor-induced sentinel lymph node lymphangiogenesis with LyP-1 peptide 

Amino Acids, 2012;42(6):2343-51. 

Zhang F, Niu G, Lin X, Jacobson O, Ma Y, Eden HS, He Y, Lu G, Chen X

296

Synergistic Enhancement of Iron Oxide Nanoparticle and Gadolinium for Dual-Contrast MRI

Biochem Biophys Res Commun, 2012;425(4):886-91.

Zhang F, Huang X, Qian C, Zhu L, Hida N, Niu G, Chen X

295

Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles

Biomaterials. 2012;33(21):5414-22.

Zhang F, Huang X, Zhu L, Guo N, Niu G, Swierczewska M, Lee S, Xu H, Wang AY, Mohamedali KA, Rosenblum MG, Lu G, Chen X

294

A quantum chemical study of the ground and excited state electronic structures of carbazole oligomers with and without triarylborane substitutes

J Phys Chem C Nanomater Interfaces. 2012;116 (23): 12434–42. 

Zhang S, Qu Z, Tao P, Brooks B, Shao Y, Chen X, Liu C

293

Positron Emission Tomography Imaging of Vascular Endothelial Growth Factor Receptor Expression with (61)Cu-Labeled Lysine-Tagged VEGF(121)

Mol Pharm. 2012; 9 (12):3586–3594

Zhang Y, Hong H, Niu G, Valdovinos HF, Orbay H, Nayak TR, Chen X, Barnhart TE, Cai W

292

Peptides in cancer nanomedicine: drug carriers, targeting ligands and protease substrates 

J Control Release, 2012;159(1):2-13.

Zhang X-X, Eden HS, Chen X

291

A Synergistically Enhanced T1-T2 Dual-Modal Contrast Agent

Adv Mater, 2012;24(46):6223-8.

Zhou Z, Huang D, Bao J, Chen Q, Chen Z, Chen X, Gao J

290

Real-time monitoring of caspase cascade activation in living cells

J Control Release, 2012; 163(1):55-62.

Zhu L, Huang X, Choi KY, Ma Y, Zhang F, Liu G, Lee S, Chen X

289

Dynamic PET and Optical Imaging and Compartment Modeling using a Dual-labeled Cyclic RGDyK Peptidic Probe

Theranostics, 2012;2(8):746-756.

Zhu L, Guo N, Li Q, Ma Y, Jacobson O, Lee S, Choi HS, Mansfield JR, Niu G, Chen X

288

99mTechnetium-HYNIC(tricine/TPPTS)-Aca-Bombesin(7-14) as a targeted imaging agent with microSPECT in a PC-3 prostate cancer xenograft model 

Mol Pharm, 2011;8(4):1165-73. 

Ananias HJ, Yu Z, Dierckx RA, van der Wiele C, Helfrich W, Wang F, Yan Y, Chen X, de Jong IJ, Elsinga PH. 

287

Striatal adenosine A2A receptor mediated PET Imaging in 6-hydroxydopamine lesioned rats using [18F]-MRS5425 

Nucl Med Biol, 2011;38(6):897-906. 

Bhattacharjee AK, Lang L, Jacobson O, Shinkre B, Ma Y, Niu G, Trenkle WC, Jacobson KA, Chen X, Kiesewetter DO 

286

Targeted nanoprobes reveal early time point kinetics in vivo by time-resolved MRI 

Theranostics 2011;1:276-278. 

Bhirde A, Guo N, Chen X 

285

Combinational portable Raman probes – nanotubes for theranostics applications 

Theranostics, 2011;1:310-21. 

Bhirde AA, Liu G, Jin A, Iglesias-Bartolome R, Sousa AA, Leapman RD, Gutkind JS, Lee S, Chen X 

284

Nanoparticles for cell labeling 

Nanoscale, 2011;3(1):142-53.

Bhirde A, Xie J, Chen X 

283

Evaluation of 99mTcN-MPO as a new myocardial perfusion imaging agent in normal dogs and acute myocardial infarction canine model: comparison with 99mTc-Sestamibi 

Mol Imaging Biol, 2011;13(1):121-7. 

Bu L, Li R, Jin Z, Wen X, Liu S, Yang B, Shen B, Chen X 

282

Phage display peptide probes for imaging early response to Bevacizumab treatment 

Amino Acids, 2011; 41(5):1103-12. 

Cao Q, Liu S, Niu G, Yan Y, Liu Z, Chen X 

281

Positron emission tomography imaging of cancer biology: current status and future prospects 

Semin Oncol, 2011;38(1):70-86. 

Chen K, Chen X 

280

Integrin targeted delivery of chemotherapeutics 

Theranostics, 2011;1:189-200. 

Chen K, Chen X 

279

Integrin targeted imaging and therapy 

Theranostics 2011;1:28-29. 

Chen X 

278

Theranostic nanomedicine 

Acc Chem Res, 2011;44(10):841. 

Chen X, Gambhir SS, Cheon J 

277

PET of insulinoma using 18F-FBEM-EM3106B, a new GLP-1 analogue 

Mol Pharm, 2011;8(5):1775-82. 

Gao H, Niu G, Yang M, Quan Q, Ma Y, Murage EN, Ahn JM, Kiesewetter DO, Chen X 

276

Affibody-based nanoprobes for HER2-expressing cell and tumor imaging 

Biomaterials, 2011;32(8):2141-8. 

Gao J, Chen K, Miao Z, Ren G, He X, Chen X, Gambhir SS, Cheng Z 

275

LC/MS evaluation of metabolism and membrane transport of bombesin peptides 

Amino Acids, 2011;40(2):669-75. 

Gu D, Ma Y, Niu G, Yan Y, Lang L, Aisaand HA, Gao HK, Kiesewetter DO, Chen X 

274

Design of “smart” probes for optical imaging of apoptosis 

Am J Nucl Med Mol Imaging, 2011;1:3-17. 

Huang X, Lee S, Chen X 

273

Prokineticin receptors antagonist PC-10 as a biomarker for imaging inflammatory pain 

J Nucl Med, 2011;52(4):600-7. 

Jacobson O, Weiss ID, Niu G, Balboni G, Congiu C, Onnis V, Kiesewetter DO, Lattanzi R, Salvadori S, Chen X 

272

PET imaging of CXCR4 using copper-64 labeled peptide antagonist 

Theranostics 2011;1:251-262. 

Jacobson O, Weiss ID, Szajek LP, Niu G, Ma Y, Kiesewetter DO, Farber JM, Chen X 

271

Rapid and simple one-step F-18 labeling of peptides 

Bioconjug Chem, 2011;22(3):422-8. 

Jacobson O, Zhu L, Ma Y, Weiss ID, Sun X, Niu G, Farber J, Kiesewetter DO, Chen X 

270

MicroPET imaging of integrin αvβ3 expressing tumors using 89Zr-RGD peptides 

Mol Imaging Biol, 2011;13(6):1224-33. 

Jacobson O, Zhu L, Niu G, Szajek L, Ma Y, Sun X, Yan Y, Kiesewetter DO, Liu S, Chen X 

269

PEGylated TNF-related apoptosis-inducing ligand (TRAIL) for effective tumor combination therapy 

Biomaterials. 2011;32(33):8529-37. 

Jiang HH, Kim TH, Lee S, Chen X, Youn YS, Lee KC. 

268

Upregulation of TRAG3 gene in urothelial carcinoma of the bladder 

Int J Cancer, 2011;128(12):2823-32. 

Karam JA, Huang S, Fan J, Stanfield J, Schultz RA, Pong RC, Sun X, Mason RP, Xie XJ, Niu G, Chen X, Frenkel EP, Sagalowsky AI, Hsieh JT 

267

Automated radiochemical synthesis of [18F]FBEM: a thiol reactive synthon for radiofluorination of peptides and proteins 

Appl Radiat Isot, 2011;69(2):410-4. 

Kiesewetter DO, Jacobson O, Lang L, Chen X 

266

PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained-release PLGA microspheres for enhanced stability and antitumor activity 

J Control Release, 2011;150(1):63-9.

Kim TH, Jiang HH, Park CW, Youn YS, Lee S, Chen X, Lee KC 

265

Mono-PEGylated dimeric exendin-4 as high receptor binding and long-acting conjugates for type 2 anti-diabetes therapeutics 

Bioconjug Chem, 2011;22(4):625-32. 

Kim TH, Jiang HH, Lee S, Youn YS, Park CW, Chen X, Lee KC 

264

Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity 

Int J Pharm, 2011;403(1-2):285-91. 

Kim TH, Jiang HH, Youn YS, Park CW, Taka KK, Lee S, Kim H, Jon S, Chen X, Lee KC 

263

PEGylated TNF-related apoptosis-inducing ligand (TRAIL) analogues: pharmacokinetics and antitumor effects 

Bioconjug Chem, 2011;22(8):1631-7. 

Kim TH, Youn YS, Jiang HH, Lee S, Chen X, Lee KC 

262

New methods for labeling RGD peptides with bromine-76 

Theranostics, 2011;1:341-53. 

Lang L, Li W, Jia HM. Fang DC, Sun X, Zhu L, Ma Y, Shen B, Kiesewetter DO, Niu G, Chen X 

261

Real time, high resolution video imaging of apoptosis in single cells with a polymeric nanoprobe 

Bioconjug Chem, 2011;22(2):125-31.

Lee S, Choi KY, Chung H, Ryu JH, Lee A, Koo H, Youn I-C, Park JH, Kim I-S, Kim SY, Chen X, Choi K, Kim K, Kwon IC 

260

Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system 

Biomaterials, 2011;32(16):4021-9. 

Lee SJ, Park S, Koo H, Lee S, Chen X, Choi Y, Leary J, Park K, Kwon IC, Kim K, Choi K 

259

Improved biological half-life and anti-tumor activity of TNF-related apoptosis-inducing ligand (TRAIL) using PEG-exposed nanoparticles 

Biomaterials, 2011;32(13):3538-46. 

Lim SM, Kim TH, Jiang HH, Park CW, Lee S, Chen X, Lee KC 

258

Protein-based molecular imaging probes 

Amino Acids, 2011;41(5):1013-36. 

Lin X, Xie J, Chen X 

257

Chimeric ferritin nanocages for multiple function loading and multimodal imaging 

Nano Lett, 2011;11 (2):814–819. 

Lin X, Xie J, Niu G, Zhang F, Gao H, Yang M, Lee S, Chen X 

256

Hybrid ferritin cages as activatable probes for tumor imaging 

Angew Chem Int Ed Engl, 2011;50(7):1569-72. 

Lin X, Xie J, Zhu L, Lee S, Niu G, Kim K, Chen X 

255

Molecular imaging of cell-based cancer immunotherapy 

Mol Biosyst, 2011; 7(4):993-1003. 

Liu G, Swierczewska M, Niu G, Zhang X, Chen X 

254

Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging 

Biomaterials, 2011;32(2):528-37. 

Liu G, Wang Z, Lu J, Xia C, Gao F, Gong Q, Song B, Zhao X, Shuai X, Chen X, Ai H, Gu H 

253

N-Alkyl-PEI-functionalized iron oxide nanoclusters for efficient siRNA delivery 

Small, 2011;7(19):2742-9. (frontispiece) 

Liu G, Xie J, Zhang F, Wang Z, Luo K, Zhu L, Quan Q, Lee S, Ai H, Chen X 

252

Specific targeting of human integrin αvβ3 with 111In-labeled AbegrinTM in nude mouse models 

Mol Imaging Biol, 2011;13(1):112-20. 

Liu Z, Jia B, Zhao H, Chen X, Wang F 

251

Integrin targeted delivery of radiotherapeutics 

Theranostics, 2011;1:201-210. 

Liu Z, Wang F, Chen X 

250

Protein and peptide probes for molecular imaging 

Amino Acids. 2011;41(5):1009-12. 

Chen X 

249

Selective imaging of mitochondrial surfaces with novel fluorescent probes 

ChemBioChem, 2011;12(14):2120-1. 

Lee S, Chen X 

248

Molecular imaging in cancer treatment 

Eur J Nucl Med Mol Imaging, 2011;38(2):358-77. 

Michalski M, Chen X 

247

First in man pharmacokinetic and dosimetry studies of [18F]FPPRGD2: A novel PET radiopharmaceutical for imaging αvβ3 integrin levels 

Radiology, 2011;260(1):182-91. 

Mittra E, Goris ML, Iagaru AH, Kardan A, Burton L, Berganos R, Chang E, Liu S, Shen B, Chin FT, Chen X, Gambhir SS 

246

Why integrin as a primary target for imaging and therapy 

Theranostics 2011;1:30-47. 

Niu G, Chen X 

245

Size effect in molecular imaging of vascular endothelial growth factor 

Chem Biol, 2011;18(7):819-20. 

Niu G, Chen X 

244

Nano delivers big: Designing molecular missiles for cancer therapeutics 

Pharmaceutics 2011;3(1):34-52. 

Patel S, Bhirde AA, Rusling JF, Chen X, Gutkind S, Patel V 

243

HSA coated iron oxide nanoparticles as drug delivery vehicles for cancer therapy 

Mol Pharm, 2011; 8(5):1669-76. 

Quan Q, Xie J, Gao H, Yang M, Zhang F, Liu G, Lin X, Wang A, Eden HS, Lee S, Zhang G, Chen X 

242

Imaging tumor endothelial marker 8 using an 18F-labeled peptide 

Eur J Nucl Med Mol Imaging, 2011;38(10):1806-15. 

Quan Q, Yang M, Gao H, Zhu L, Lin X, Guo N, Zhang G, Eden HS, Niu G, Chen X 

241

Coenzyme Q functionalized CdTe/ZnS quantum dots for reactive oxygen species (ROS) imaging 

Chemistry 2011;17(19):5262-71. 

Qin LX, Ma W, Li DW, Li Y, Chen X, Kraatz HB, James TD, Long YT 

240

Tumor hypoxia imaging 

Mol Imaging Biol, 2011;13(3):399-410. 

Sun X, Niu G, Chan N, Shen B, Chen X 

239

18F-FPPRGD2 and 18F-FDG PET imaging of Abraxane therapy response 

J Nucl Med, 2011;52(1):140-6. 

Sun X, Yan Y, Liu S, Niu G, Cao Q, Yang M, Neamati N, Shen B, Chen X 

238

The design and application of fluorophore-gold nanoparticle activatable probes 

Phys Chem Chem Phys, 2011;13(21):9929-41. 

Swierczewska M, Lee S, Chen X 

237

Inorganic nanoparticles for multimodal molecular imaging 

Mol Imaging, 2011;10(1):3-16. 

Swierczewska M, Lee S, Chen X 

236

Molecular imaging of microRNAs 

Eur J Nucl Med Mol Imaging 2011;38(8):1572-9. 

Wang F, Niu G, Chen X, Cao F 

235

Ferritin enhances SPIO tracking of C6 rat glioma cells by MRI 

Mol Imaging Biol, 2010; 13(1):87-93. 

Wang J, Xie J, Zhou X, Cheng Z, Gu N, Teng G, Hu Q, Zhu F, Chang S, Zhang F, Lu G, Chen X 

234

Surface-engineered magnetic nanoparticle platforms as cancer theranostics 

Acc Chem Res, 2011;44(10):883-92. 

Xie J, Liu G, Eden HS, Chen X 

233

Multi-quenched flower-like Au-Fe3O4 nanoparticles for protease determination in vivo 

ACS Nano, 2011;5(4):3043-51. 

Xie J, Zhu L, Lin X, Zhang F, Choi KY, Kim K, Kwon IC, Lee S, Sun S, Leapman R, Chen X 

232

Functional MnO nanoclusters for efficient siRNA delivery 

Chem Comm (Cambridge), 2011;47(44):12152-4.

Xing R, Liu G, Quan Q, Bhirde A, Zhang G, Jin A, Zhang A, Liang A, Bryant LH, Eden HS, Hou Y, Chen X 

231

Polyaspartic acid coated manganese oxide nanoparticles for efficent liver MRI 

Nanoscale, 2011;3(12):4943-5. 

Xing R, Zhang F, Xie J, Aronova M, Zhang G, Guo N, Huang X, Sun X, Liu G, Liang A, Hou Y, Leapman RD, Sun S, Chen X 

230

A new 18F-labeled BBN-RGD peptide heterodimer with a symmetric linker for prostate cancer imaging 

Amino Acids, 2011;41(2):439-47. 

Yan Y, Chen K, Yang M, Sun X, Liu S, Chen X 

229

Peptide heterodimers for molecular imaging 

Amino Acids, 2011;41(5):1081-92. 

Yan Y, Chen X 

228

Multiplexed PET probes for imaging breast cancer early response to VEGF121/rGel treatment 

Mol Pharm, 2011;8(2):621-8. 

Yang M, Gao H, Sun X, Yan Y, Zhang W, Mohamedali K, Rosenblum MG, Quan Q, Niu G, Chen X 

227

PET imaging of early response to the tyrosine kinase inhibitor ZD4190 

Eur J Nucl Med Mol Imaging, 2011;38(7):1237-47. 

Yang M, Gao H, Yan Y, Sun X, Chen K, Quan Q, Lang L, Kiesewetter DO, Niu G, Chen X 

226

18F-Labeled bombesin receptor agonist and antagonist: A comparative study in prostate cancer imaging 

Theranostics, 2011;1:220-229. 

Yang M, Gao H, Zhou Y, Ma Y, Quan Q, Zhu L, Lang L, Chen K, Niu G, Yan Y, Chen X 

225

Integrin targeting for tumor optical imaging 

Theranostics 2011;1:102-126. 

Ye Y, Chen X 

224

Synthesis and evaluation of new iRGD peptide analogs for tumor optical imaging 

Bioorg Med Chem Lett, 2011;21(4):1146-1150.

Ye Y, Zhu L, Ma Y, Niu G, Chen X 

223

Organic high ionic strength aqueous two-phase solvent system series for separation of ultra-polar compounds by spiral high-speed counter-current chromatography 

J Chromatogr A. 2011;1218(48):8715-7. 

Zeng Y, Liu G, Ma Y, Chen X, Ito Y 

222

Preclinical lymphatic imaging 

Mol Imaging Biol, 2011;13(4):599-612. 

Zhang F, Niu G, Lu G, Chen X 

221

In vivo MRI tracking of cell invasion and migration in a rat glioma model 

Mol Imaging Biol, 2011;13(4):695-701. 

Zhang F, Xie J, Liu G, He Y, Lu G, Chen X 

220

Multimodality imaging of tumor response to Doxil 

Theranostics, 2011;1:302-309. 

Zhang F, Zhu L, Liu G, Hida N, Lu G, Eden HS, Niu G, Chen X 

219

Single gold nanoparticles as real-time optical probes for the detection of NADH-dependent intracellular metabolic enzymatic pathways 

Angew Chem Int Ed Engl, 2011;50(30):6789-92. 

Zhang L, Li Y, Li DW, Jing C, Chen X, Lv M, Huang Q, Long YT, Willner I 

218

64Cu-labeled lissamine rhodamine B: a promising PET radiotracer targeting tumor mitochondria 

Mol Pharm, 2011;8(4):1198-208. 

Zhou Y, Kim Y-S, Jacobson O, Chen X, Liu S 

217

Evaluation of 64Cu-labeled acridinium cation: A PET radiotracer targeting tumor mitochondria 

Bioconjug Chem, 2011; 22(4):700-8. 

Zhou Y, Kim Y-S, Shi J, Jacobson O, Chen X, Liu S 

216

High-affinity peptide against MT1-MMP for in vivo tumor imaging 

J Control Release, 2011;150(3):248-255. (Cover feature) 

Zhu L, Wang H-L, Wang L, Wang Y, Jiang K, Li Cheng, Ma Q, Gao S, Wang L, Li W, Cai M-J, Wang D-H, Niu G, Lee S, Yang W, Fang XX, Chen X 

215

Dual-functional, receptor-targeted fluorogenic probe for in vivo imaging of extracellular protease expressions 

Bioconjug Chem, 2011;22(6):1001-5. 

Zhu L, Xie J, Swierczewska M, Zhang F, Lin X, Fang X, Niu G, Lee S, Chen X 

214

Real-time video imaging of protease expression in vivo 

Theranostics, 2011;1:18-27. 

Zhu L, Xie J, Zhang F, Quan Q, Ma Y, Niu G, Kim K, Lee S, Chen X 

213

The biological effect of an antisense oligonucleotide depends on its route of endocytosis and trafficking 

Oligonucleotides, 2010;20(2):103-9. 

Alam MR, Min X, Dixit V, Fisher M, Chen X, Juliano RL 

212

Design of targeted cardiovascular molecular imaging probes 

J Nucl Med, 2010;51 Suppl 1:3S-17S. 

Anderson CJ, Bulte JWM, Chen K, Chen X, Khaw B-A, Shokeem M, Wooley KL, VanBrocklin HF 

211

Imaging of angiogenesis: from morphology to molecules and from bench to bedside 

Eur J Nucl Med Mol Imaging, 2010;37(Suppl 1):S1-3. 

Beer AJ, Chen X 

210

Design and development of molecular imaging probes 

Curr Top Med Chem, 2010;10(12):1227-36. 

Chen K, Chen X 

209

The medicinal chemistry of targeted tumor imaging (I) 

Curr Top Med Chem, 2010;10(11):1046-7. 

Chen X 

208

The medicinal chemistry of targeted tumor imaging (II) 

Curr Top Med Chem, 2010;10(12):1145-6. 

Chen X 

207

Molecular imaging of tumor microenvironment 

Q J Nucl Med Mol Imaging, 2010;54(3):243. 

Chen X, Del Vecchio S 

206

Ultrahigh sensitivity carbon nanotube agents for photoacoustic molecular imaging in living mice 

Nano Lett, 2010;10(6):2168-72. 

de la Zerda A, Liu Z, Bodapati S, Teed R, Vaithilingam S, Khuri-Yakub BT, Chen X, Dai H, Gambhir SS 

205

Ultrasmall near-infrared non-cadmium quantum dots for in vivo tumor imaging 

Small, 2010;6(2):256-61. 

Gao J, Chen K, Xie R, Xie J, Lee S, Gambhir SS, Peng X, Chen X 

204

In vivo tumor-targeted fluorescence imaging using near-infrared non-cadmium quantum dots 

Bioconjug Chem, 2010;21(4):604-9. 

Gao J, Chen K, Xie R, Xie J, Yan Y, Peng X, Chen X 

203

Near-infrared quantum dots as optical probes for tumor imaging 

Curr Top Med Chem, 2010;10(12):1147-57. 

Gao J, Chen X, Cheng Z 

202

Positron emission tomography tracers for imaging angiogenesis 

Eur J Nucl Med Mol Imaging, 2010;37(Suppl 1):S86-103. 

Haubner R, Beer AJ, Wang H, Chen X 

201

Effects of nanoparticle size on cellular uptake and liver MRI with polyvinylpyrrolidone-coated iron oxide nanoparticles 

ACS Nano, 2010;4(12):7151-60. 

Huang J, Bu L, Xie J, Chen K, Cheng Z, Li X, Chen X 

200

HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging 

Chem Comm (Camb), 2010;46(36):6684-6. 

Huang J, Xie J, Chen K, Bu L, Cheng Z, Li X, Chen X 

199

PET designated flouride-18 production and chemistry 

Curr Top Med Chem, 2010;10(11):1048-59. 

Jacobson O, Chen X 

198

PET Imaging of Tumor CXCR4 Expression with 4-18F-T140 

J Nucl Med, 2010;51(11):1796–1804 

Jacobson O, Weiss ID, Kiesewetter DO, Farber JM, Chen X 

197

Soft-solution route to ZnO nanowall array with low threshold power density 

Appl Phys Lett, 2010;97:043109. 

Jang E-S, Chen X, Won J-H, Chung J-H, Jang D-J, Kim Y-W, Choy J-H 

196

Soft-solution route to various ZnO nanoplate arrays 

CrystEngComm, 2010;12(11):3467-3470. 

Jang ES, Won JH, Kim YW, Chen X, Choy JH 

195

Peptide-based probes for targeted molecular imaging 

Biochemistry, 2010; 49(7):1364-76 

Lee S, Xie J, Chen X

194

Peptides and peptide hormones for molecular imaging and disease diagnosis 

Chem Rev, 2010;110(5):3087-111. 

Lee S, Xie J, Chen X 

193

Activatable moleuclar probes for cancer imaging 

Curr Top Med Chem, 2010;10(11):1135-44. 

Lee S, Xie J, Chen X 

192

Functional nanoparticles for molecular imaging guided gene delivery 

Nano Today, 2010;5(6):524-539. 

Liu G, Swierczewska M, Lee S, Chen X 

191

In vivo quantitative bioluminescence tomography on heterogeneous and homogeneous mouse models 

Opt Express, 2010;18(12):13102-13. 

Liu J, Wang Y, Hu Z, Li X, Ma X, Sun D, Zhang R, Chen D, Chen D, Chen X, Laing J, Cao F, Tian J 

190

18F-labeled galacto and PEGylated RGD dimers for PET imaging of αvβ3 integrin expression 

Mol Imaging Biol, 2010;12(5):530-8. 

Liu S, Liu Z, Chen K, Yan Y, Watzlowik P, Wester H-J, Chin FT, Chen X 

189

Optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers 

Mol Imaging, 2010;9(1):21-9. 

Liu Z, Liu S, Niu G, Wang F, Liu S, Chen X 

188

Epidermal growth factor receptor-targeted radioimmunotherapy of human head and neck cancer xenografts using 90Y-labeled fully human antibody panitumumab 

Mol Cancer Ther, 2010;9(8):2297-308. 

Liu Z, Liu Y, Jia B, Zhao H, Jin X, Li F, Chen X, Wang F 

187

Applications of LC-MS in PET radioligand development and metabolic elucidation 

Curr Drug Metab, 2010;11(6):483-93. 

Ma Y, Kiesewetter DO, Lang L, Gu D, Chen X 

186

Preparative isolation and purification of optical imaging probe-Cybesin by counter-current chromatography 

J Chromatogr B Analyt Technol Biomed Life Sci. 2010;878(29):3039-43. 

Ma Z, Ma Y, Sun X, Ye Y, Shen B, Chen X, Ito Y 

185

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor 

Nucl Acid Res, 2010;38(19):6567-76. 

Ming X, Alam MR, Fisher M, Yan Y, Chen X, Juliano RL 

184

Vascular endothelial growth factor as an anti-angiogenic target for cancer therapy 

Curr Drug Targets, 2010;11(8):1000-17. 

Niu G, Chen X 

183

Imaging of Apoptosis: Beyond Annexin V 

J Nucl Med, 2010; 51(11):1659–1662 

Niu G, Chen X 

182

Cetuximab-based immunotherapy and radioimmunotherapy of head and neck squamous cell carcinoma 

Clin Cancer Res, 2010;16:2095-105. (Cover feature) 

Niu G, Sun X, Cao Q, Courter D, Koong A, Le Q-T, Gambhir SS, Chen X 

181

Biodistribution of neural stem cells after intravascular therapy for hypoxic-ischemia 

Stroke, 2010;41(9):2064-70 

Pendharkar AV, Chua JY, Andres RH, Wang N, Gaeta X, Wang H, De A, Choi R, Chen X, Rutt BK, Gambhir SS, Guzman R 

180

Firefly luciferase-based dynamic bioluminescence imaging: a noninvasive technique to assess tumor angiogenesis 

Neurosurgery, 2010;66(4):751-7; discussion 757. 

Sun A, Hou L, Prugpichailers T, Dunkel J, Kalani MA, Chen X, Kalani MYS, Tse V 

179

Phage display library derived peptides for osteosarcoma imaging 

Clin Cancer Res, 2010;16(16):4268-4277. 

Sun X, Niu G, Yan Y, Yang M, Chen K, Ma Y, Chan N, Shen B, Chen X 

178

MR reporter gene imaging of endostatin expression and therapy 

Mol Imaging Biol, 2010;12(5):520-9. 

Wang K, Wang K, Shen B, Huang T, Sun X, Li W, Jin G, Li L, Bu L, Li R, Wang D, Chen X 

177

PET/NIRF/MRI triple functional iron oxide nanoparticles

Biomaterials, 2010;31(11):3016-22. 

Xie J, Chen K, Huang J, Lee S, Wang J, Gao J, Li X, Chen X 

176

Development of theranostic agents that co-deliver therapeutic and imaging agents 

Adv Drug Deliv Rev, 2010;62:1064-1079. 

Xie J, Lee S, Chen X 

175

Human serum albumin coated iron oxide nanoparticles for efficient cell labeling 

Chem Comm (Camb), 2010;46(3):433-5. 

Xie J, Wang J, Niu G, Huang J, Chen K, Li X, Gong H, Chen X 

174

Treatment of cystic craniopharyngioma with phosphorus-32 intracavitary irradiation 

Childs Nerv Syst, 2010;26(5):669-74. 

Zhao R, Deng J, Liang X, Zeng J, Chen X, Wang J 

173

Preclinical imaging of angiogenesis 

Q J Nucl Med Mol Imaging, 2010;54(3):291-308. 

Zhu L, Niu G, Fang X, Chen X 

172

Positron emission tomography imaging of poststroke angiogenesis 

Stroke, 2009;40(1):270-7. 

Cai W, Guzman R, Hsu AR, Wang H, Chen K, Sun G, Gera A, Choi R, Bliss T, He L, Li ZB, Maag AL, Hori N, Zhao H, Moseley M, Steinberg GK, Chen X 

171

PET imaging of angiogenesis formation in teratoma from human embryonic stem cells 

Cancer Res, 2009;69(7):2709-13.

Cao F, Li Z, Chen K, Wang H, Cai W, Chen X, Wu JC 

170

Quantitative PET imaging of VEGF receptor expression 

Mol Imaging Biol, 2009;11(1):15-22. 

Chen K, Cai W, Li Z-B, Wang H, Chen X 

169

RGD-human serum albumin conjugates as efficient tumor targeting probes 

Mol Imaging, 2009;8(2):65-73. 

Chen K, Xie J, Chen X 

168

Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting 

Biomaterials, 2009;30(36):6912-9. 

Chen K, Xie J, Xu H, Behera D, Michalski MH, Biswal S, Wang A, Chen X 

167

Dual-modality probes for in vivo molecular imaging 

Mol Imaging, 2009;8(2):87-100. (Cover feature) 

Lee S, Chen X 

166

Polymeric nanoparticle-based activatable near-infrared nanosensor for protease determination in vivo 

Nano Lett, 2009;9(12):4412-6. 

Lee S, Ryu JH, Park K, Lee A, Lee SY, Youn IC, Ahn CH, Yoon SM, Myung SJ, Moon DH, Chen X, Choi K, Kwon IC, Kim K 

165

64Cu-labeled PEGylated polyethylenimine for cell trafficking and tumor imaging 

Mol Imaging Biol, 2009;11(6):415-23. 

Li ZB, Chen K, Wu Z, Wang H, Niu G, Chen X 

164

Supramolecular stacking of doxorubicin on carbon nanotubes for in vivo cancer therapy 

Angew Chem Int Engl, 2009;48(41):7668-72. 

Liu Z, Fan AC, Rakhra K, Sherlock S, Goodwin A, Chen X, Yang Q, Felsher DW, Dai H 

163

Small animal PET of tumors with 64Cu-labeled RGD-bombesin heterodimer 

J Nucl Med, 2009;50(7):1168-1177. 

Liu Z, Li Z-B, Cao Q, Liu S, Wang F, Chen X 

162

Non-invasive imaging of tumor integrin expression using 18F-labeled RGD dimer peptide with PEG4 linkers 

Eur J Nucl Med Mol Imaging, 2009; 36(8):1296-307. 

Liu Z, Liu S, Wang F, Liu S, Chen X 

161

68Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin αvβ3 PET imaging 

Eur J Nucl Med Mol Imaging, 2009;36(6):947-57. 

Liu Z, Shi J, Niu G, Liu S, Wang F, Liu S, Chen X 

160

68Ga-labeled NOTA-RGD-BBN peptide for dual integrin and GRPR targeted tumor imaging 

Eur J Nucl Med Mol Imaging, 2009; 36(9):1483-94. 

Liu Z, Niu G, Wang F, Chen X 

159

Dual integrin and GRPR targeted tumor imaging using 18F-labeled PEGylated BBN-RGD heterodimer 18F-PEG3-Glu-RGD-BBN 

J Med Chem, 2009;52(2):425-32. 

Liu Z, Yan Y, Chin FT, Wang F, Chen X 

158

18F, 64Cu, and 68Ga labeled RGD-bombesin heterodimeric peptides for PET imaging of breast cancer 

Bioconjug Chem, 2009; 20(5):1016–1025. 

Liu Z, Yan Y, Liu S, Wang F, Chen X 

157

From protein-protein interaction to therapy response: molecular imaging of heat shock proteins 

Eur J Radiol, 2009;70(2):294-304. 

Niu G, Chen X 

156

Noninvasive visualization of microRNA by bioluminescence imaging 

Mol Imaging Biol, 2009;11(2):61-3. 

Niu G, Chen X 

155

The role of molecular imaging in drug delivery 

Drug Delivery, 2009;3:109-113. 

Niu G, Chen X 

154

PET imaging of angiogenesis 

PET Clinics, 2009;4(1):17-38. 

Niu G, Chen X 

153

Monitoring therapeutic response of human ovarian cancer to 17-DMAG by noninvasive PET imaging with 64Cu-DOTA-trastuzumab 

Eur J Nucl Med Mol Imaging, 2009; 36(9):1510-9. 

Niu G, Li Z, Cao Q, Chen X 

152

PET imaging antibody delivery in EGFR positive head-neck squamous cell carcinoma models 

J Nucl Med, 2009;50(7):1116-23. 

Niu G, Li Z, Xie J, Le Q-T, Chen X 

151

Limb remote postconditioning protects against focal ischemia in rats 

Brain Res, 2009;1288:88-94. 

Ren C, Yan Z, Wei D, Gao X, Chen X, Zhao H 

150

Improving tumor uptake and pharmacokinetics of 64Cu-labeled cyclic RGD peptide dimers with Gly3 and PEG4 linkers 

Bioconjug Chem, 2009;20(4):750-9. 

Shi J, Kim YS, Zhai S, Liu Z, Chen X, Liu S 

149

Rapid intracerebroventricular delivery of Cu-DOTA-etanercept after peripheral administration demonstrated by PET imaging 

BMC Res Notes, 2009;2:28. 

Tobinick EL, Chen K, Chen X 

148

Production, modification and bio-applications of magnetic nanoparticles gestated by magnetotactic bacteria 

Nano Res, 2009;2:261-78. 

Xie J, Chen K, Chen X 

147

Iron oxide nanoparticle platform for biomedical applications 

Curr Med Chem, 2009;16(10):1278-94. 

Xie J, Huang J, Li X, Sun S, Chen X 

146

Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging 

Stem Cells, 2009; 27(7):1548-58. 

Wang H, Cao F, De A, Cao YA, Contag CH, Gambhir SS, Wu JC, Chen X 

145

Site-specifically biotinylated VEGF121 for near-infrared fluorescence imaging of tumor angiogenesis 

Mol Pharm, 2009;6(1):285-94. 

Wang H, Chen K, Niu G, Chen X 

144

Applications for site-directed molecular imaging agents coupled with drug delivery potential 

Expert Opin Drug Deliv, 2009;6(7):745-68. 

Wang H, Chen X 

143

Characterizing breast cancer xenograft epidermal growth factor receptor expression by using near-infrared optical imaging 

Acta Radiol, 2009;50(10):1095-103. 

Wang K, Wang K, Li W, Huang T, Li R, Wang D, Shen B, Chen X 

142

Improving tumor-targeting capability and pharmacokinetics of 99mTc-labeled cyclic RGD dimers with PEG4 linkers 

Mol Pharm, 2009;6(1):231-45. 

Wang L, Shi J, Kim Y-S, Zhai S, Jia B, Zhao H, Liu Z, Wang F, Chen X, Liu S 

141

Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis 

Nucl Acid Res, 2008;36(8):2764-76. 

Alam MR, Dixiti V, Kang H, Li ZB, Chen X, Juliano R. 

140

Multimodality molecular imaging of tumor angiogenesis 

J Nucl Med, 2008;49(Suppl 2):113S-128S. 

Cai W, Chen X 

139

Preparation of peptide conjugated quantum dots for targeted cancer imaging 

Nat Protocol 2008;3(1):89-96.

Cai W, Chen X 

138

Chapter 7. Molecular imaging of tumor vasculature 

Methods Enzymol. 2008;445:141-76. 

Cai W, Gambhir SS, Chen X 

137

Molecular Imaging of the HER-Kinase Axis in cancer 

Eur J Nucl Med Mol Imaging, 2008;35(1):186-208. 

Cai W, Niu G, Chen X 

136

Imaging of integrins as biomarkers for tumor angiogenesis 

Curr Pharm Des, 2008;14(28):2943-73. 

Cai W, Niu G, Chen X 

135

Multimodality imaging of IL-18--binding protein-Fc therapy of experimental lung metastasis 

Clin Cancer Res, 2008;14(19):6137-45. 

Cao Q, Cai W, Niu G, He L, Chen X 

134

Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide-paclitaxel conjugate in mice with breast cancer 

Eur J Nucl Med Mol Imaging, 2008;35(8):1489-98. 

Cao Q, Li Z-B, Chen K, Wu Z, He L, Neamati N, Chen X 

133

Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots 

Eur J Nucl Med Mol Imaging, 2008;35(12):2235-44. 

Chen K, Li ZB, Wang H, Cai W, Chen X 

132

Semiautomated radiosynthesis and biological evaluation of [18F]FEAU: a novel PET imaging agent for HSV1-tk/sr39tk reporter gene expression 

Mol Imaging Biol, 2008;10(2):82-91. 

Chin FT, Namavari M, Levi J, Subbarayan M, Ray P, Chen X, Gambhir SS 

131

Carbon nanotubes as photoacoustic molecular imaging agents in living mice 

Nat Nanotechnol, 2008;3(9):557-62. 

De la Zerda A, Zavaleta C, Keren S, Vaithilingam S, Bodapati S, Liu Z, Levi J, Smith BR, Ma TJ, Oralkan O, Cheng Z, Chen X, Dai H, Khuri-Yakub BT, Gambhir SS 

130

Short hairpin RNA interference therapy for ischemic heart disease 

Circulation, 2008;118(14 Suppl):S226-33. 

Huang M, Chan D, Jia F, Xie X, Li Z, Hoyt G, Robbins RC, Chen X, Giaccia A, Wu JC 

129

Advances in anatomical, functional and molecular imaging of angiogenesis 

J Nucl Med, 2008;49(4):511-514. 

Hsu AR, Chen X 

128

Molecular imaging as the main part of our decision-making and treatment strategies in stroke 

Front Biosci, 2008;13:1535-1556. 

Kashefi A, Zhao H, Chen X 

127

Effects of targeting moiety, linker, bifunctional chelator, and molecular charge on biological properties of 64Cu-labeled triphenylphosphonium cations 

J Med Chem, 2008;51(10):2971-84. 

Kim YS, Yang CT, Wang J, Wang L, Li ZB, Chen X, Liu S 

126

Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent 

Nanotechnology, 2008;19(16): 165101. 

Lee HY, Lee SH, Xu C, Xie J, Lee JH, Wu B, Koh AL, Wang X, Sinclair R, Wang SX, Nishimura DG, Biswal S, Sun S, Cho SH, Chen X 

125

PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles 

J Nucl Med, 2008;49(8):1371-9. 

Lee HY, Li Z, Chen K, Hsu AR, Xu C, Xie J, Sun S, Chen X 

124

68Ga-labeled multimeric RGD peptides for microPET imaging of αvβ3 integrin expression 

Eur J Nucl Med Mol Imaging, 2008;35(6):1100-8. 

Li ZB, Chen K, Chen X. 

123

Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET 

Clin Cancer Res, 2008;14(15):4758-66. 

Li ZB, Niu G, Wang H, He L, Ploug M, Chen X 

122

The synthesis of 18F-FDS and its potential application in molecular imaging 

Mol Imaging Biol, 2008;10(2):92-8. 

Li ZB, Wu Z, Cao Q, Tseng J, Gambhir SS, Chen X 

121

18F-labeled BBN-RGD heterodimer for prostate cancer imaging 

J Nucl Med, 2008;49(3):453-61. 

Li ZB, Wu Z, Chen K, Ryu E-K, Chen X 

120

Drug delivery with carbon nanotubes for in vivo cancer treatment 

Cancer Res, 2008;68(16):6552-6560. (Cover feature) 

Liu Z, Chen K, Davis C, Sherlock S, Cao Q, Chen X, Dai H 

119

Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy 

Proc Natl Acad Sci U S A. 2008;105(5):1410-5. 

Liu Z, Davis C, Cai W, He L, Chen X, Dai H 

118

Integrin αvβ3 targeted cancer therapy 

Drug Dev Res, 2008;69(6):329-39. 

Liu Z, Wang F, Chen X 

117

Non-invasive PET imaging of EGFR degradation induced by heat shock protein 90 inhibitor 

Mol Imaging Biol, 2008;10(2):99-106. 

Niu G, Cai W, Chen K, Chen X 

116

Molecular imaging of human epidermal growth factor receptor 2 (HER-2) expression 

Front Biosci, 2008;13:790-805. 

Niu G, Cai W, Chen X 

115

Has molecular and cellular imaging enhanced drug discovery and drug development? 

Drugs R D, 2008;9(6):351-68. 

Niu G, Chen X 

114

Delayed postconditioning protects against focal ischemic brain injury in rats 

PloS ONE, 2008;3(12):e3851. 

Ren C, Gao X, Niu G, Yan Z, Chen X, Zhao H 

113

Imaging of VEGF receptor in a rat myocardial infarction model using PET 

J Nucl Med, 2008;49(4):667-673. 

Rodriguez-Porcel M, Cai W, Gheysens O, Chen I, Chen K, He L, Willman J, Wu JC, Chen X, Gambhir SS 

112

Molecular imaging for Alzheimer’s disease 

Front Biosci, 2008;13:777-789. 

Ryu EK, Chen X 

111

Synthesis of a potent and selective 18F-labeled delta-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for positron emission tomography imaging 

J Med Chem, 2008;51(6):1817-23. 

Ryu EK, Wu Z, Chen K, Lazarus LH, Marczak ED, Sasaki Y, Ambo A, Salvadori S, Ren C, Zhao H, Balboni G, Chen X

110

Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice 

Small, 2008;5(1):126-34. 

Schipper ML, Iyer G, Koh AL, Cheng Z, Ebenstein Y, Aharoni A, Keren S, Bentolila LA, Li J, Rao J, Chen X, Banin U, Wu AM, Sinclair R, Weiss S, Gambhir SS 

109

99mTc-labeled bombesin(7-14)NH2 with favorable properties for SPECT imaging of colon cancer 

Bioconjug Chem, 2008;19(6):1170-8. 

Shi J, Jia B, Liu Z, Yang Z, Yu Z, Chen K, Chen X, Liu S, Wang F 

108

Improving tumor uptake and excretion kinetics of 99mTc-labeled cyclic arginine-glycine-aspartic (RGD) dimers with triglycine linkers 

J Med Chem, 2008;51(24):7980-90. 

Shi J, Wang L, Kim YS, Zhai S, Liu Z, Chen X, Liu S 

107

The temporal correlation of dynamic contrast-enhanced magnetic resonance imaging with tumor angiogenesis in a murine glioblastoma model 

Neurol Res. 2008;30(9):952-9. 

Veeravagu A, Hou LC, Hsu AR, Cai W, Greve JM, Chen X, Tse V 

106

Integrin-αvβ3 targeted radioimmunotherapy of glioblastoma multiforme 

Clin Cancer Res, 2008;14(22):7330-9. 

Veeravagu A, Liu Z, Niu G, Chen K, Jia B, Cai W, Jin C, Hsu AR, Connolly AJ, Tse V, Wang F, Chen X 

105

Integrin-targeted imaging and therapy with RGD4C-TNF fusion protein 

Mol Cancer Ther, 2008;7(5):1044-53. 

Wang H, Chen K, Cai W, Li Z, He L, Kashefi A, Chen X 

104

Site-specifically modified fusion protein for molecular imaging 

Front Biosci, 2008;13:1716-32. 

Wang H, Chen X 

103

Imaging mesenchymal stem cell migration and the implications for stem cell-based cancer therapies 

Future Oncol, 2008;4(5):623-8. 

Wang H, Chen X 

102

US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice

Radiology, 2008;246(2):508-18. 

Willman JK, Paulmurugan R, Chen K, Gheysens O, Rodriguez-Porcel M, Lutz AM, Chen IY, Chen X, Gambhir SS 

101

Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography 

Circulation, 2008;117(7):915-22. 

Willmann JK, Chen K, Wang H, Paulmurugan P, Rollins M, Cai W, Wang D, Chen IY, Chen X, Gambhir SS 

100

Ultrasmall c(RGDyK)-coated Fe3O4 nanoparticles and their specific targeting to integrin αvβ3-rich tumor cells 

J Am Chem Soc, 2008;130(24):7542-3. 

Xie J, Chen K, Lee H-Y, Xu C, Hsu AR, Peng S, Chen X, Sun S 

99

InAs/InP/ZnSe core/shell/shell quantum dots as near-infrared emitters: bright, narrow-band, non-cadmium, and biocompatible 

Nano Res, 2008;1(6):457-64. 

Xie R, Chen K, Chen X, Peng X 

98

64Cu-labeled 2-(diphenylphosphoryl)ethyldiphenylphosphonium cations as highly selective tumor imaging agents: effects of linkers and chelates on radiotracer biodistribution characteristics 

Bioconjug Chem, 2008;19(10):2008-22. 

Yang CT, Kim YS, Wang J, Wang L, Shi J, Li ZB, Chen X, Fan M, Li JJ, Liu S 

97

Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes 

Nano Lett, 2008;8(9):2800-5. 

Zavaleta C, de la Zerda A, Liu Z, Keren S, Cheng Z, Schipper M, Chen X, Dai H, Gambhir SS 

96

Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody 

Eur J Nucl Med Mol Imaging, 2007;34(6):850-8. 

Cai W, Chen K, He L, Cao Q, Koong A, Chen X 

95

Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature 

J Nucl Med, 2007;48(11):1862-70. 

Cai W, Chen K, Li ZB, Gambhir SS, Chen X 

94

Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression 

Front Biosci. 2007;12:4267-79. 

Cai W, Chen X 

93

Nanoplatforms for targeted molecular imaging in living subjects 

Small, 2007;3(11):1840-54. (Inside cover) 

Cai W, Chen X 

92

Quantitative radioimmunoPET imaging of EphA2 in living mice 

Eur J Nucl Med Mol Imaging 2007;34(12):2024-36. 

Cai W, Ebrahimnejad A, Chen K, Cao Q, Li Z-B, Tice DA, Chen X 

91

Are quantum dots ready for in vivo imaging in human subjects? 

Nanoscale Res Lett, 2007;2(6):265-81. 

Cai W, Hsu AR, Li ZB, Chen X 

90

PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody 

J Nucl Med, 2007;48(2):304-10. 

Cai W, Olafsen T, Zhang X, Cao Q, Gambhir SS, Williams LE, Wu AM, Chen X 

89

PET of acute and chronic inflammation in living mice 

Eur J Nucl Med Mol Imaging, 2007;34(11):1832-42. 

Cao Q, Cai W, Li ZB, Chen K, He L, Li HC, Hui M, Chen X 

88

64Cu-labeled alpha-melanocyte-stimulating hormone analog for microPET imaging of melanocortin 1 receptor expression 

Bioconjug Chem 2007;18(3):765-72. 

Cheng Z, Xiong Z, Subbarayan M, Chen X, Gambhir SS 

87

Small-animal PET of melanocortin 1 receptor expression using a 18F-labeled alpha-melanocyte-stimulating hormone analog 

J Nucl Med. 2007;48:987-94. 

Cheng Z, Zhang L, Graves E, Xiong Z, Dandekar M, Chen X, Gambhir SS 

86

Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel 

J Nucl Med, 2007;48(3):445-54. 

Hsu AR, Cai W, Veeravagu A, Mohamedali KA, Chen K, Kim S, Vogel H, Hou LC, Tse V, Rosenblum MG, Chen X 

85

Integrin avβ3 antagonists for anti-angiogenic cancer treatment 

Recent Pat Anticancer Drug Discov, 2007;2(2):143-160.

Hsu AR, Veeravagu A, Cai W, Hou LC, Tse VC, Chen X 

84

Anticancer drug-phospholipid conjugate for enhancement of intracellular drug delivery 

Macromol Symp 2007;249-250(1):109-15. 

Hwang T, Han HD, Song CK, Seong H, Kim JH, Chen X, Shin BC 

83

Molecular imaging can accelerate anti-angiogenic drug development and testing 

Nat Clin Pract Oncol, 2007;4(10):556-7. 

Iagaru A, Chen X, Gambhir SS 

82

Semiconductor quantum dots for in vivo imaging 

J Nanosci Nanotechnol, 2007;7(8):2567-81. 

Li Z, Cai W, Chen X 

81

64Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor avβ3 integrin expression 

J Nucl Med, 2007;48(7):1162-71. 

Li ZB, Cai W, Cao Q, Chen K, Wu Z, He L, Chen X 

80

Click chemistry for 18F-labeling of RGD peptides and microPET imaging of tumor integrin αvβ3 expression 

Bioconjug Chem, 2007;18(6):1987-94. 

Li ZB, Wu Z, Chen K, Chin FT, Chen X. 

79

Evaluation of a 99mTc-labeled cyclic RGD tetramer for noninvasive imaging integrin αvβ3-positive breast cancer 

Bioconjug Chem, 2007;18(2):438-46. 

Liu S, Hsieh WY, Jiang Y, Kim YS, Sreerama SG, Chen X, Jia B, Wang F 

78

In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice 

Nat Nanotechnol, 2007;2(1):47-52. 

Liu Z, Cai W, He L, Nakayama N, Chen K, Sun X, Chen X, Dai H 

77

In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene 

Mol Imaging Biol, 2007;9(3):126-34. 

Niu G, Xiong Z, Cheng Z, Cai W, Gambhir SS, Xing L, Chen X 

76

microPET-based biodistribution of quantum dots in living mice 

J Nucl Med, 2007;48(9):1511-8. 

Schipper ML, Cheng Z, Lee SW, Bentolila LA, Iyer G, Rao J, Chen X, Wu AM, Weiss S, Gambhir SS 

75

Vascular endothelial growth factor and vascular endothelial growth factor receptor inhibitors as anti-angiogenic agents in cancer therapy 

Recent Pat Anticancer Drug Discov, 2007;2(1):59-71. 

Veeravagu A, Hsu AR, Cai W, Hou LC, Tse VC, Chen X 

74

A new PET tracer specific for vascular endothelial growth factor receptor 2 

Eur J Nucl Med Mol Imaging, 2007;34(12):2001-2010. 

Wang H, Cai W, Chen K, Li ZB, Kashefi A, He L, Chen X 

73

64Cu-Labeled triphenylphosphonium and triphenylarsonium cations as highly tumor-selective imaging agents 

J Med Chem, 2007;50(21):5057-69. 

Wang J, Yang CT, Kim YS, Sreerama SG, Cao Q, Li ZB, He Z, Chen X, Liu S 

72

microPET of tumor avβ3 integrin expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4) 

J Nucl Med, 2007;48(9):1536-44. 

Wu Z, Li ZB, Chen K, Cai W, He L, Chin FT, Li F, Chen X 

71

18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of avβ3 integrin expression 

Eur J Nucl Med Mol Imaging 2007;34(11):1823-31. 

Wu Z, Li ZB, Cai W, He L, Chin FT, Li F, Chen X 

70

Preparation and characterization of 99mTc(CO)3-BPy-RGD complex as αvβ3 integrin receptor targeted imaging agent 

Appl Radiat Isot, 2007;65(1):70-8. 

Zhang X, Chen X. 

69

PET of vascular endothelial growth factor receptor expression 

J Nucl Med. 2006;47(12):2048-56. 

Cai W, Chen K, Mohamedali KA, Cao Q, Gambhir SS, Rosenblum MG, Chen X 

68

Anti-angiogenic cancer therapy based on integrin αvβ3 antagonism 

Anticancer Agents Med Chem, 2006;6(5):407-28. 

Cai W, Chen X. 

67

How molecular imaging is speeding up antiangiogenic drug development 

Mol Cancer Ther. 2006;5(11): 2624-33. 

Cai W, Rao J, Gambhir SS, Chen X 

66

Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects 

Nano Lett, 2006;6(4):669-676. 

Cai W, Shin DW, Chen K, Gheysens O, Cao Q, Wang SX, Gambhir SS, Chen X 

65

In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin avβ3 

Cancer Res, 2006;66(19):9673-81. 

Cai W, Wu Y, Chen K, Cao Q, Tice DA, Chen X 

64

A thiol-reactive 18F-labeling agent, N-[2-(4-18F-fluorobenzamido)ethyl]maleimide, and synthesis of RGD peptide-based tracer for PET imaging of avβ3 integrin expression 

J Nucl Med, 2006;47(7):1172-1180. 

Cai W, Zhang X, Wu Y, Chen X. 

63

In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery 

Circulation, 2006;113(7):1005-14. 

Cao F, Lin S, Krishnan M, Ray P, Patel M, Drukker M, Dylla SJ, Connolly AJ, Chen X, Weissman I, Gambhir SS, Wu JC 

62

Combination of integrin siRNA and irradiation for breast cancer therapy 

Biochem Biophys Res Commun, 2006; 351(3):726-32. 

Cao Q, Cai W, Li T, Yang Y, Chen K, Xing L, Chen X 

61

Multimodality imaging of tumor integrin αvβ3 expression 

Mini Rev Med Chem, 2006;6(2):227-34. 

Chen X 

60

Significance of one-bead-one-compound combinational chemistry 

Nat Chem Biol. 2006;2(7):351-2. 

Chen X, Gambhir SS. 

59

Longitudinal microPET imaging of brain tumor growth with F-18-labeled RGD peptide 

Mol Imaging Biol, 2006;8(1):9-15. 

Chen X, Park R, Khankaldyyan V, Gonzales-Gomez I, Tohme M, Moats RA, Bading JR, Laug WE, Conti PS 

58

Near-infrared fluorescent deoxyglucose analogue for tumor optical imaging in cell culture and living mice 

Bioconjug Chem, 2006;17(3):662-9. 

Cheng Z, Levi J, Xiong Z, Gheysens O, Keren S, Chen X, Gambhir SS 

57

Discovery of small molecule integrin αvβ3 antagonists as novel anticancer agents 

J Med Chem, 2006;49(15):4526-34. 

Dayam R, Aiello F, Wu Y, Garofalo A, Chen X, Neamati N. 

56

In vivo near-infrared fluorescence imaging of integrin αvβ3 in an orthotopic glioblastoma model 

Mol Imaging Biol. 2006;8(6):315-23. 

Hsu AR, Hou LC, Veeravagu A, Greve JM, Vogel H, Tse V, Chen X 

55

Near-infrared fluorescence imaging of tumor integrin αvβ3 expression with Cy7-labeled RGD multimers 

Mol Imaging Biol, 2006;8(4):226-36. 

Wu Y, W Cai, Chen X. 

54

Imaging chemically modified adenovirus for targeting tumors expressing integrin αvβ3 in living mice with mutant herpes simplex virus type 1 thymidine kinase PET reporter gene 

J Nucl Med, 2006;47(1):130-9. (Cover feature) 

Xiong Z, Cheng Z, Zhang X, Patel M, Wu JC, Gambhir SS, Chen X. 

53

MicroPET imaging of gastrin-releasing peptide receptor expression with 64Cu-labeled bombesin analogs in a mouse model of human prostate adenocarcinoma 

Nucl Med Biol, 2006;33(3):371-80. 

Yang YS, Zhang X, Xiong Z, Chen X. 

52

18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer 

J Nucl Med, 2006;47(3):492-501.

Zhang X, Cai W, Cao F, Schreibmann E, Wu Y, Wu JC, Xing L, Chen X 

51

Quantitative PET imaging of tumor integrin avβ3 expression with 18F-FRGD2 

J Nucl Med, 2006;47(1):113-121. 

Zhang X, Xiong Z, Wu Y, Tseng JR, Gambhir SS, Chen X. 

50

Multimodality iumor imaging targeting integrin avβ3 

Biotechniques, 2005;39(6 Suppl):S14-25. 

Cai W, Gambhir SS, Chen X 

49

Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery 

J Med Chem 2005;48(4):1098-106. 

Chen X, Plasencia C, Hou Y, Neamati N. 

48

Integrin avb3 targeted imaging of lung cancer 

Neoplasia 2005;7(3):271-9. 

Chen X, Sievers E, Hou Y, Park R, Tohme M, Bart R, Bremner R, Bading JR, Conti PS 

47

Synthesis of (4-[18F]fluorophenyl)triphenylphosphonium as a potential imaging agent for mitochondrial dysfunction 

J Labelled Compds Radiopharm, 2005;48:131-7. 

Cheng Z, Subbarayan M, Chen X, Gambhir SS. 

46

Near-infrared fluorescent RGD peptides for optical imaging of integrin avβ3 expression in living mice 

Bioconjug Chem. 2005;16(6):1433-41.

Cheng Z, Wu Y, Xiong Z, Gambhir SS, Chen X 

45

Comparison of [14C]FMAU, [3H]FEAU, [14C]FIAU, and [3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type 1 thymidine kinase in cell culture 

Mol Imaging Biol, 2005;7(4):296-303. 

Kang KW, Min JJ, Chen X, Gambhir SS. 

44

MicroPET imaging of glioma alpha(v)-integrin expression using 64Cu-labeled tetrameric RGD peptide 

J Nucl Med, 2005;46(10):1707-1718. 

Wu Y, Zhang X, Xiong Z, Cheng Z, Fisher Dr, Liu S, Gambhir SS, Chen X. 

43

In vivo near-infrared fluorescence imaging of integrin avb3 in brain tumor xenografts 

Cancer Res 2004;64:8009-14. 

Chen X, Conti PS, Moats RA 

42

Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor αvβ3-integrin expression 

J Nucl Med, 2004;45(10):1776-83. 

Chen X, Hou Y, Tohme M, Park R, Khankaldyyan V, Gonzales-Gomez I, Bading JR, Laug WE, Conti PS. 

41

MicroPET imaging of breast cancer av-integrin expression with 64Cu-labeled dimeric RGD peptides 

Mol Imaging Biol, 2004;6(5):350-9. 

Chen X, Liu S, Hou Y, Tohme M, Park R, Bading JR, Conti PS. 

40

microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts 

J Nucl Med, 2004;45(8):1390-7. (Cover feature) 

Chen X, Park R, Hou Y, Tohme M, Shahinian AH, Bading JR, Conti PS 

39

MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide 

Eur J Nucl Med Mol Imaging, 2004;31(8):1081-9. 

Chen X, Park R, Khankaldyyan V, Tohme M, Bading JR, Laug WE, Conti PS. 

38

Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation 

Nucl Med Biol, 2004;31(1):11-9. 

Chen X, Park R, Shahinian AH, Bading JR, Conti PS 

37

18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis 

Nucl Med Biol, 2004;31(2):179-89. 

Chen X, Park R, Shahinian AH, Tohme M, Khankaldyyan V, Bozorgzadeh MH, Bading JR, Moats R, Laug WE, Conti PS 

36

MicroPET and autoradiographic imaging of breast cancer av-integrin expression using 18F- and 64Cu-labeled RGD peptide 

Bioconjug Chem, 2004;15(1):41-9. 

Chen X, Park R, Tohme M, Bading JR, Conti PS 

35

MicroPET imaging of avβ3 integrin expression with 18F-labeled dimeric RGD peptide 

Mol Imaging, 2004;3(2):96-104. 

Chen X, Tohme M, Park R, Hou Y, Bading JR, Conti PS. 

34

Unusual magnetic properties of one-dimensional molecule-based magnets associated with a structural phase transition 

Inorg Chem 2002;41:5686-92. 

Ren X, Meng Q, Song Y, Lu C, Hu C, Chen X

33

Unusual magnetic property associated with dimerization within a nickel tetramer 

Inorg Chem 2002;41:5931-3. 

Ren, X, Meng Q, Song Y, Hu C, Lu C, Chen X, Xue Z 

32

Synthesis, crystal structure and magnetic properties of [RbzPy] [Fe(mnt)2] complexes ([RbzPy]+ = 1-(4’-R-benzyl)pyridinium, R = NO2 and Cl; mnt2 = maleonitriledithiolate) 

Transition Met Chem 2002;27:394-7.

Ren X, Wu P, Zhang W, Meng Q, Chen X 

31

Spectroscopic and structural studies of complexes of the fac-[Re(N∩N)(CO)3L]n+ type (N∩N=2-(2-pyridyl)benzothiazole; L=Cl, Br, CF3SO3−, CH3CN) 

Inorg Chim Acta  2001;314:91-6. 

Chen X, Femia FJ, Babich, JW, Zubieta J  

30

Synthesis, characterization and crystal structures of mono-, di- and trinuclear rhenium(I) tricarbonyl complexes with 2,3,5,6-tetra(2-pyridyl)pyrazine 

Inorg Chim Acta  2001;315:66-72 

Chen X, Femia FJ, Babich, JW, Zubieta J  

29

Synthesis and structural characterization of rhenium(I) tricarbonyl complexes with the bidentate ligands o-(diphenylphosphino)benzaldehyde (P∩O) and o-[(diphenylphosphino)benzylidene]analine (P∩N)  

Inorg Chim Acta 2001;315:147-52 

Chen X, Femia FJ, Babich, JW, Zubieta J  

28

Schiff base chemistry of the rhenium(V)-oxo core with “3+2” ligand donor sets 

Inorg Chim Acta  2001;316:33-40 

Chen X, Femia FJ, Babich, JW, Zubieta J  

27

Rhenium(I) carbonyl complexes of 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPT). Rhenium (I)-promoted methoxylation of the triazine ring carbon atom in dinuclear rhenium complexes  

Inorg Chem 2001;40:2769-77.

Chen X, Femia FJ, Babich, JW, Zubieta J  

26

Synthesis and characterization of a '3+2' {Re(V)O}3+ core complex carrying the ONS/PO donor atom set

Inorg Chim Acta  2001;316:145-8. 

Femia FJ, Chen X, Babich JW, Zubieta J

25

Oxorhenium(V) complexes containing tridentate Schiff-base and monothiol coligands  

Inorg Chim Acta  2000;300-302:517-524. 

Femia, FJ, Chen X, Babich, JW, Zubieta J 

24

Synthesis and characterization of complexes of the {ReO}3+ core with SNS and S donor ligands  

Inorg Chim Acta  2000;306:30-37. 

Femia, FJ, Chen X, Maresca KP, Shoup, TM, Babich, JW, Zubieta J

23

Investigations of the {ReO}3+ core: A “2+2” complex from bidentate and potentially trident ligands: [ReO(η2-HOC6H4-2-CH2NC6H4S)(η2-SC5H4N)(PPh3)]

Inorg Chim Acta  2000;306:38-41. 

Chen X, Femia FJ, Babich, JW, Zubieta J 

22

Structural characterizations of an Re(IV) complex [ReCl4(OPPh3)2] and of an imino species [ReOCl2(PPh3)(2-OC6H4-2-CH=NH)] prepared from the reaction of [ReOCl3(PPh3)2] with salicylaldoxime  

Inorg Chim Acta  2000;306:112-5. 

Chen X, Femia FJ, Babich, JW, Zubieta J.  

21

Synthesis and characterization of oxorhenium(V)–‘3+1’ mixed thiolate [SNS]/[S] and [ONS]/[S] complexes. Crystal and molecular structures of [ReO(η3-SCH2C5H3NCH2S)(η1-C6H4Br-4-S)], [ReO(η3-SCH2C5H3NCH2O)(η1-C6H4X-4-S)] (X=Cl, OMe), [ReO(η3-SCH2C5H3NCH2O)(η1-C6H4OCH3-4-CH2S)] and [ReO(η3-SCH2C5H3NCH2S)(η1-C5H4NH-2-S)][Cl]

Inorg Chim Acta  2000;307:88-96.

Chen X, Femia FJ, Babich, JW, Zubieta J.  

20

Schiff base chemistry of the {ReO}3+ core: structural characterization of the unusual “3+2” complex [ReO(η3-OC6H4–CH=NC6H4-2-S)(η2-OC6H4C=NC6H4-2-S)] 

Inorg Chim Acta  2000;307:149-153. 

Chen X, Femia FJ, Babich, JW, Zubieta J 

19

Exploring oxorhenium “3+1” mixed-ligand complexes carrying the S-benzyl-3-[(2-hydroxyphenyl)methylene]dithiocarbazate [ONS]/monothiol [S] donor set: synthesis and characterization 

Inorg Chim Acta  2000;307:154-9. 

Chen X, Femia FJ, Babich, JW, Zubieta J.  

18

Synthesis and crystal and molecular structure of a tetranuclear cluster based on the rhenium(III)-bisorganohydrazino core: [Re(HNNC4H3N2)(NNC4H3N2)(OCH3)2]4

Inorg Chim Acta  2000;307:160-3. 

Femia, FJ, Chen X, Maresca KP, Babich, JW, Zubieta J.  

17

The syntheses and structures of “3+2” and “2+2+1” oxorhenium mixed-ligand complexes employing 8-hydroxy-5-nitroquinoline as the bidentate N,O donor ligand 

Inorg Chim Acta  2000;308:80-90. 

Chen X, Femia FJ, Babich, JW, Zubieta J.  

16

Syntheses and structural characterization of rhenium-bis-hydrazinopyrimidine core complexes with thiolate and Schiff base coligands

Inorg Chim Acta  2000;310:210-6. 

Femia, FJ, Chen X, Maresca KP, Babich, JW, Zubieta J  

15

An unexpected “4+2” [N3S]/[NS] rhenium(IV) complex formed upon cleavage of a Re(V) imido bond 

Inorg Chim Acta  2000;310:237-41. 

Chen X, Femia FJ, Babich, JW, Zubieta J  

14

Synthesis, structure, spectral and magnetic properties of a dinuclear copper(II)/nickel(II) complex bridged by glyoximate groups   

Polyhedron  1999;18(15):2035-9. 

Zhan S, Hu C, Chen X, Meng Q, Lu C, Wang G, Zheng P.   

13

Synthesis, studies and molecular structure of trinuclear cyanide-bridged copper-iron complexes 

Inorg Chim Acta  1999;292(2):157-62. 

Zhan S, Chen X, Vij A, Guo D, Meng Q.   

12

Synthesizing and dispersing silver nanoparticles in a water-in-supercritical carbon dioxide microemulsion    

J Am Chem Soc  1999;121:2631-2. 

Ji M, Chen X, Wai CM, Fulton JL.   

11

Selective extraction of strontium by supercritical fluid carbon dioxide  

Chem Commun (Cambridge) 1999:2533-2534. 

Wai CM, Kulyako Y, Yak, H-K, Chen X, Lee S-J.  

10

Monofunctionalization of calix[4]arene tetracarboxylic acid at the upper rim with isothiocyanate group: first bifunctional chelating agent for alpha-emitter Ac-225  

Synlett 1999;11:1784-6. 

Chen X, Ji M, Fisher DR, Wai CM.   

9

Ionizable calixarene-crown ethers with high selectivity for radium over lighter alkaline earth metal ions  

Inorg Chem 1999;38(23):5449-52. 

Chen X, Ji M, Fisher DR, Wai CM  

8

Carboxylate-derived calixarenes with high selectivity for actinium-225  

Chem Commun (Cambridge) 1998:377-8. 

Chen X, Ji M, Fisher DR, Wai CM.   

7

Chemical reactions in supercritical carbon dioxide  

J Chem Edu  1998;75:641-5. 

Wai CM, Hunt F, Ji M, Chen X. 

6

Synthesis, electrochemical and magnetic properties of Cu3 complexes of a series of new compartmental trinucleating ligands H4L   

J Chem Soc Dalton Trans. 1997:245-50. 

Chen X, Zhan S, Hu C, Meng Q, Liu Y.   

5

Binickel(II) complex of a new asymmetrical acyclic ligand: the X-ray crystal structure of [Ni2L](ClO4)2 reveals alternating square-planar and octahedral nickel ions   

Inorg Chim Acta  1997;260(1):95-8. 

Chen X, Zhan S, Hu C, Meng Q, Shun  J.  

4

Synthesis, characterization and electrochemical properties of cyanide-bridged cobalt(III)/iron(II) complexes    

Syn React Inorg Met-Org Chem 1996;26(2):277-84. 

Zhang S, Chen X, Meng Q, Xie W.

3

Synthesis and properties of cyano-bridged nickel(II)-iron(III) complexes    

Transition Met Chem (London) 1996;21(2):181-3. 

Zhan S, Chen X, Meng Q.

2

Synthesis and Spectroscopic Studies of Trinuclear Uranyl Complexes with Compartmental Ligands H4L Derived From 2,6-Dipicolinoyl-hydrazine and 4-Acyl-1-Phenyl-3-Methyl-Pyrazolones-5 (Where Acyl = Benzoyl, Acetyl, iso-Butyryl or iso-Valeroyl)   

Transition Met Chem (London) 1996;21(4):345-8.

Chen X, Zhan S, Meng Q.   

1

Kinetic study of nucleophilic substitution reactions of N-methylimidazole with hemin chloride   

J Inorg Chem 1995;11(2):192-7. 

Chen X, Zhang X, Meng Q, Sweigart DA. 

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