


Publications before 2016
505
Antibody-Drug Conjugates
Bioconjug Chem. 2015 Nov 18;26(11):2169. [Front Cover]
Peng L, Chen X
504
A novel self-assembled sandwich nanomedicine for NIR-responsive release of NO
Nanoscale. 2015;7(47):20055-62.
Fan J, He N, He Q, Liu Y, Ma Y, Fu X, Liu Y, Huang P, Chen X
503
Gold Nanoparticle Strings Wrap up into Plasmonic Vesicles for Enhanced Photoacoustic Imaging
Angew Chem Int Ed Engl, 2015;54:15809-12. (Back cover)
Liu Y, He J, Yang K, Yi C, Liu Y, Nie L, Khashab NM, Chen X, Nie Z
502
Photoacoustic and Colorimetric Visualization of Latent Fingerprints
ACS Nano, 2015 Dec 22;9(12):12344-8.
Song K, Huang P, Yi C, Ning B, Hu S, Nie L, Chen X, Nie Z
501
Improving Cell-Based Therapies by Nanomodification
J Control Release, 2015;219:560-75.
Chen W, Fu L, Chen X
500
68Ga-NOTA-PRGD2 PET/CT for Integrin Imaging in Patients with Lung Cancer.
J Nucl Med, 2015;56(12):1823-7.
Zheng K, Liang N, Zhang J, Lang L, Zhang W, Li S, Zhao J, Li F, Zhu Z, Chen X
499
Virus-Mimetic Nanovesicles as a Versatile Antigen Delivery System
Proc Natl Acad Sci U S A, 2015; 112(45):E6129-38.
Zhang P, Chen Y, Zeng Y, Chu C, Tian R, Guo Z, Zheng Z, Li R, Sheng C, Wang Z, Li S, Ge S, Zhang X, Xia N, Liu G, Chen X
498
Noninvasive Dynamic Imaging of Tumor Microenvironment in Response to Nanoparticle-Mediated Photothermal Therapy
Theranostics, 2015; 5(12):1444-1455.
Zhang F, Cao J, Chen X, Yang K, Zhu L, Fu G, Huang X, Chen X
497
Penetrating the Blood Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles
ACS Nano, 2015;9(10):9470-4.
Ali IU, Chen X
496
Sequential Drug Release and Enhanced Photothermal Effect of Hybrid Reduced Graphene Oxide-Loaded Ultrasmall Gold Nanorod Vesicles for Cancer Therapy
ACS Nano, 2015; 9(9):9199-209.
Song J, Yang X, Jacobson O, Lin L, Huang P, Niu G, Ma Q, Chen X
495
NIR-responsive on-demand release of CO from metal carbonyl-caged graphene oxide nanomedicine
Adv Mater, 2015;27(42):6741-6. (Front Cover)
He Q, Kiesewetter DO, Fu X, Fan J, Huang P, Liu Y, Zhu G, Liu Y, Qian Z, Chen X
494
Tumor-specific formation of enzyme instructed supramolecular self-assemblies as cancer theranostics
ACS Nano, 2015;9(10):9517-27.
Huang P, Gao Y, Lin J, Hu H, Liao H-S, Yan X, Tang Y, Jin A, Song J, Niu G, Zhang G, Horkay F, Chen X
493
18F-labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression
J Nucl Med, 2015;56(11):1780-5.
Jacobson O, Weiss ID, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu G, Kiesewetter DO, Vasdev, Liang SH, Chen X
492
Protein-Based Photothermal Theranostics for Imaging-Guided Cancer Therapy
Nanoscale, 2015;7(39):16330-6.
Rong P, Huang P, Liu Z, Lin J, Jin A, Ma Y, Niu G, Yu L, Zeng W, Wang W, Chen X
491
Clinical Translation of an Albumin-Binding PET Radiotracer 68Ga-NEB.
J Nucl Med, 2015; 56(10):1609-14.
Zhang J, Lang L, Li F, Zhu Z, Niu G, Chen X
490
Ortho-stabilized 18F-azido click agents and application in PET imaging of single-stranded DNA aptamer
Angew Chem Int Ed Engl, 2015; 54(43):12777-81.
Wang L, Jacobson O, Avdic D, Rotstein BH, Weiss ID, Collier L, Chen X, Vasdev N, Liang SH
489
Aptamer-drug conjugates.
Bioconjug Chem. 2015; 26(11):2186-97.
Zhu G, Niu G, Chen X
488
Boramino Acid as a Marker for Amino Acid Transporters
Sci Adv, 2015;1:e150069. [Highlighted by C&EN News]
Liu Z, Chen H, Chen K, Shao Y, Kiesewetter DO, Niu G, Chen X
487
Accelerating the Translation of Nanomaterials in Biomedicine.
ACS Nano. 2015;9(7):6644-54.
Mitragotri S, Anderson DG, Chen X, Chow EK, Ho D, Kabanov AV, Karp JM, Kataoka K, Mirkin CA, Petrosko SH, Shi J, Stevens MM, Sun S, Teoh S, Venkatraman SS, Xia Y, Wang S, Gu Z, Xu C.
486
Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy
Adv Mater, 2015;27(33):4910-7 (Front Cover).
Song J, Yang X, Jacobson O, Huang P, Sun X, Lin L, Yan X, Niu G, Ma Q, Chen X
485
A Novel Method for Simultaneous Radiolabeling and Dimerizing Thiolated Peptides Using 18F-Hexafluorobenzene
Bioconjugate Chem, 2015; 26(10):2016-20. (Front Cover)
Jacobosn O, Yan X, Ma Y, Niu Gm Kiesewetter DO, Chen X
484
18F-Alfatide II PET/CT in healthy human volunteers and patients with brain metastases
Eur J Nucl Med Mol Imaging, 2015; 42(13):2021-8.
Yu C, Pan D, Mi B, Xu Y, Lang L, Niu G, Yang M, Wan W, Chen X
483
Development of Individualized Anti-Metastasis Strategies by Engineering Nanomedicines
Chem Soc Rev, 2015; 44(17):6258-86.
He Q, Guo S, Qian Z, Chen X
482
Pilot Prospective Evaluation of 18F-Alfatide II for Detection of Skeletal Metastases
Theranostics, 2015; 5(10):1115-1121.
Mi B, Yu C, Pan D, Yang M, Wan W, Niu G, Chen X
481
Gold Nanoparticles for In Vitro Diagnostics
Chem Rev, 2015; 115(19):10575-636
Zhou W, Gao X, Liu D, Chen X
480
Plasmonic Vesicles of Amphiphilic Nanocrystals: Optically Active Multifunctional Platform for Cancer Diagnosis and Therapy
Acc Chem Res, 2015; 48(9):2506-15.
Song J, Huang P, Duan H, Chen X
479
One-step (18)F labeling of biomolecules using organotrifluoroborates
Nat Protoc, 2015;10(9):1423-32.
Liu Z, Lin K-S, Benard F, Pourghiasian M, Kiesewetter DO, Perrin DM, Chen X
478
Suspension array based on nanoparticle-encoded microspheres for high-throughput multiplexed detection
Chem Soc Rev, 2015;44(15):5552-95.
Leng Y, Sun K, Chen X, Li W
477
Polymeric Nanovehicle Regulated Spatiotemporal Real-Time Imaging of the Differentiation Dynamics of Transplanted Neural Stem Cells after Traumatic Brain Injury
ACS Nano, 2015;9(7):6683-95.
Wang Z, Zhang M, Wang L, Wang S, Kang F, Li G, Jacobson O, Niu G, Yang W, Wang J, Chen X.
476
Protein phosphatase 2A inhibition with LB100 enhances radiation-induced mitotic catastrophe and tumor growth delay in glioblastoma
Mol Cancer Ther. 2015;14(7):1540-7.
Gordon IK, Lu J, Graves CA, Huntoon K, Frerich JM, Hanson RH, Wang X, Hong CS, Ho W, Feldman MJ, Ikejiri B, Bisht K, Chen XS, Tandle A, Yang C, Arscott WT, Ye D, Heiss JD, Lonser R, Camphausen K, Zhuang Z
475
Co9 Se8 Nanoplates as a New Theranostic Platform for Photoacoustic/Magnetic Resonance Dual-Modal-Imaging-Guided Chemo-Photothermal Combination Therapy.
Adv Mater. 2015;27(21):3285-91.
Song XR, Wang X, Yu SX, Cao J, Li SH, Li J, Liu G, Yang HH, Chen X
474
Quantitative Evaluation of Tumor Early Response to a Vascular Disrupting Agent with Dynamic PET
Mol Imaging Biol, 2015; 17(6):865-73.
Guo N, Zhang F, Zhang X, Guo J, Lang L, Kiesewetter DO, Niu G, Li Q, Chen X
473
Prospective Study of 68Ga-NOTA-NFB: Radiation Dosimetry in Healthy Volunteers and First Application in Glioma Patients
Theranostics, 2015; 5(8): 882-889.
Wang Z, Zhang M, Wang L, Wang S, Kang F, Li Q, Jacobson O, Niu G, Yang W, Wang J, Chen X
472
Lymphatic Imaging: Focus on Imaging Probes
Theranostics, 2015; 5(7): 686-697.
Niu G, Chen X
471
Semimetal nanomaterials of antimony as highly efficient agent for photoacoustic imaging and photothermal therapy.
Biomaterials. 2015;45:18-26.
Li W, Rong P, Yang K, Huang P, Sun K, Chen X
470
Aptamer-Targeting Photoresponsive Drug Delivery System Using “Off-On” Graphene Oxide Wrapped Mesoporous Silica Nanoparticles
Nanoscale, 2015;7(14):6304-10.
Tang Y, Hu H, Zhang MG, Song J, Nie L, Wang S, Niu G, Huang P, Lu G, Chen X
469
Gold nanoparticles for photoacoustic imaging
Nanomedicine (Lond). 2015;10(2):299-320.
Li W, Chen X.
468
Kinetic Analysis of Dynamic 11C-acetate PET/CT Imaging as a Potential Method for Differentiation of Hepatocellular Carcinoma and Benign Liver Lesions
Theranostics, 2015; 5(4): 371-377.
Huo L, Guo J, Dang Y, Lv J, Zheng Y, Li F, Xie Q, Chen X
467
Quantitative Molecular Magnetic Resonance Imaging of Angiogenesis In Vivo using Polyvalent Cyclic RGD-Iron Oxide Microparticle Conjugates
Theranostics, 2015; 5(5):515-529.
Melemenidis S, Jefferson A, Ruparelia N, Akhtar AM, Xie J, Allen D, Hamilton A, Larkin JR, Perez-Balderas F, Smart SC, Muschel RJ, Chen X, Sibson NR, Choudhury RP
466
Molecular Imaging of Apoptosis: From Micro to Macro
Theranostics, 2015; 5(6):559-582.
Zeng W, Wang X, Xu P, Liu G, Eden HS, Chen X
465
Reversibly Extracellular pH Controlled Cellular Uptake and Photothermal Therapy by PEGylated Mixed-Charge Gold Nanostars
Small. 2015 Apr;11(15):1801-1810. (Inside front cover)
Wang S, Teng Z, Huang P, Liu D, Liu Y, Tian Y, Sun J, Li Y, Ju H, Chen X, Lu G
464
Optical and photoacoustic dual-modality imaging guided synergistic photodynamic/photothermal therapies
Nanoscale. 2015; 7(6):2520-6.
Yan X, Hu H, Lin J, Jin AJ, Niu G, Zhang S, Huang P, Shen B, Chen X
463
Nanoscintillator-Mediated X-ray Inducible Photodynamic Therapy for In Vivo Cancer Treatment.
Nano Lett. 2015; 15(4):2249-56.
Chen H, Wang GD, Chuang YJ, Zhen Z, Chen X, Biddinger P, Hao Z, Liu F, Shen B, Pan Z, Xie J.
462
Positron Emission Tomography Imaging Using Radiolabeled Inorganic Nanomaterials
Acc Chem Res, 2015;48(2):286-94.
Sun X, Cai W, Chen X
461
Design of a functional cyclic HSV1-TK reporter for PET imaging of apoptosis
Nat Protoc, 2015;10(5):807-21.
Wang Z, Wang F, Hida N, Kiesewetter DO, Tian J, Niu G, Chen X
460
Intrinsically Radioactive [64Cu]CuInS/ZnS Quantum Dots for PET and Optical Imaging: Improved Radiochemical Stability and Controllable Cerenkov Luminescence
ACS Nano, 2015; 9(1):488-95.
Guo W, Sun X, Jacobson O, Yan , Min K, Srivatsan A, Niu G, Kiesewetter DO, Chang J, Chen X
459
pH-Controlled Gas-Generating Mineralized Nanoparticles: A Theranostic Agent for Ultrasound Imaging and Therapy of Cancers
ACS Nano, 2015;9(1):134-45.
Min KH, Min HS, Lee HJ, Park DJ, Silvestre OF, Chen X, Yhee JY, Kim K, Kwon IC, Jeong SY, Hwang Y-S, Lee SC
458
Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes
Bioconjugate Chem, 2015; 26(1):1-18.
Jacobson O, Kiesewetter DO, Chen X
457
PEGylated Exendin-4, a modified GLP-1 analog exhibits longer-lasting cardioprotection than its unmodified parent molecule in a murine model of myocardial infarction
Theranostics, 2015; 5(3): 240-250.
Sun Z, Tong G, Kim TH, Ma N, Niu G, Cao F, Chen X
456
68Ga-NOTA-exendin-4 PET/CT in detection of occult insulinoma and evaluation of physiological uptake
Eur J Nucl Med Mol Imaging, 2015; 42(3):531-2. [Image of the month]
Luo Y, Yu M, Pan Q, Wu W, Zhang T, Kiesewetter DO, Zhu Z, Li F, Chen X, Zhao Y
455
Enhanced Fluorescence Imaging Guided Photodynamic Therapy of Sinoporphyrin Sodium Loaded Graphene Oxide
Biomaterials, 2015;42:94-102.
Yan X, Huang P, Niu G, Lin J, Jin AJ, Hu H, Zhang Y, Wu A, Lu J, Zhang S, Shen B, Chen X
454
PET Imaging of Tenascin-C with a Radiolabeled Single-Strand DNA Aptamer
J Nucl Med, 2015;56(4):616-21.
Jacobson O, Yan X, Niu G, Weiss ID, Ma Y, Szajek LP, Shen B, Kiesewetter DO, Chen X
453
In Vivo Albumin Labeling and Lymphatic Imaging
Proc Natl Acad Sci U S A, 2015;112:208-213
Wang Y, Lang L, Huang P, Wang Z, Jacobson O, Kiesewetter DO, Ali I, Teng G, Niu G, Chen X
452
Engineered Mesenchymal Stem Cells with Enhanced Tropism and Paracrine Secretion of Cytokines and Growth Factors to Treat Traumatic Brain Injury
Stem Cells, 2015; 33(2):456-67
Wang Z, Wang Y, Wang Z, Huang P, Wang Z, Patel V, Gutkind JS, Lu J, Niu G, Teng G, Chen X
451
Bioinspired Nanocomplex for Spatiotemporal Imaging of Sequential mRNA Expression in Differentiating Neural Stem Cells
ACS Nano, 2014; 8(12):12386-96.
Wang Z, Zhang R, Wang Z, Wang HF, Wang Y, Zhao J, Wang F, Li W, Niu G, Kiesewetter DO, Chen X
450
Early-stage imaging of nanocarrier enhanced chemotherapy response in living subjects by scalable photoacoustic microscopy
ACS Nano, 2014; 8(12):12141-50.
Nie L, Huang P, Li W, Wang Z, Tang Y, Jin AJ, Wang S, Zhang F, Niu G, Chen X
449
Recent advances in nanoparticle-based nuclear imaging of cancers.
Adv Cancer Res. 2014;124:83-129.
Srivatsan A, Chen X.
448
Mercaptopropionic acid-capped Mn2+:ZnSe/ZnO quantum dots with both downconversion and upconversion emissions for bioimaging applications.
Nanoscale. 2014 Oct 9;6(21):12345-9.
Zhao B, Yao Y, Yang K, Rong P, Huang P, Sun K, An X, Li Z, Chen X, Li W.
447
Attenuation of lung cancer stem cell tumorigenesis and metastasis by cisplatin
Exp Lung Res. 2014 Oct;40(8):404-14.
Wang S, Ma S, Li X, Xue Z, Zhang X, Fan W, Nie Y, Wu K, Chen X, Cao F.
446
A Novel 19F Activatable Probe for the Detection of Matrix Metalloprotease-2 Activity by MRI/MRS
Mol Pharm, 2014;11(11):4208-17.
Yue X, Wang Z, Zhu L, Wang Y, Qian C, Ma Y, Kiesewetter DO, Niu G, Chen X
445
PET and NIR Optical Imaging Using Self-Illuminating 64Cu-Doped Chelator-Free Gold Nanoclusters
Biomaterials, 2014 Dec;35(37):9868-76.
Hu H, Huang P, Weiss OJ, Yan X, Yue X, Zhang MG, Tang Y, Nie L, Ma Y, Niu G, Wu K, Chen X
444
In vivo quantitative photoacoustic microscopy of gold nanostar kinetics in mouse organs
Biomed Opt Express. 2014;5(8):2679-85.
Li W, Sun X, Wang Y, Niu G, Chen X, Qian Z, Nie L.
443
Dye Loaded Ferritin Nanocages for Multimodal Imaging and Photothermal Therapy
Adv Mater, 2014 Oct;26(37):6401-8.
Huang P, Rong P, Jin A, Yan X, Zhang MG, Lin J, Hu H, Wang Z, Yue X, Li W, Niu G, Zeng W, Wang W, Zhou K, Chen X
442
Intraoperative Imaging-Guided Cancer Surgery: From Current Optical Molecular Imaging Methods to Future Multi-Modality Imaging Technology
Theranostics, 2014; 4(11):1072-1084.
Chi C, Du Y, Ye J, Kou D, Qiu J, Wang J, Tian J, Chen X
441
Quantitative proteomics analysis identifies mitochondria as therapeutic targets of multidrug-resistance in ovarian cancer
Theranostics, 2014; 4(12): 1164-1175.
Chen X, Wei S, Ma Y, Lu J, Niu G, Xue Y, Chen X, Yang F
440
Transient absorption microscopy of gold nanorods as spectrally orthogonal labels in live cells
Nanoscale. 2014 Sep 21;6(18):10536-9.
Chen T, Chen S, Zhou J, Liang D, Chen X, Huang Y.
439
The Interplay between Longitudinal and Transverse Contrasts in Fe3O4 Nanoplates with (111) Exposed Surfaces
ACS Nano. 2014 Aug 26;8(8):7976-85.
Zhou Z, Zhao Z, Zhang H, Wang Z, Chen X, Wang R, Chen Z, Gao J.
438
68Ga-PRGD2 PET/CT in the evaluation of glioma: a prospective study
Mol Pharm. 2014;11(11):3923-9.
Li D, Zhao X, Zhang L, Li F, Ji N, Gao Z, Wang J, Kang P, Liu Z, Shi J, Chen X, Zhu Z.
437
Role of Albumin in the Formation and Stabilization of Nanoparticle Aggregates in Serum Studied by Continuous Photon Correlation Spectroscopy and Multiscale Computer Simulations
J Phys Chem C 2014, 118, 16199-16208
Bhirde AA, Hassan SA, Harr E, Chen X
436
Chelator-Free 64Cu-Integrated Gold Nanomaterials for Positron Emission Tomography Imaging Guided Photothermal Cancer Therapy.
ACS Nano. 2014 Aug 26;8(8):8438-46.
Sun X, Huang X, Yan X, Wang Y, Guo J, Jacobson O, Liu D, Szajek LP, Zhu W, Niu G, Kiesewetter DO, Sun S, Chen X.
435
Application of (68)Ga-PRGD2 PET/CT for αvβ3-integrin Imaging of Myocardial Infarction and Stroke.
Theranostics. 2014 May 25;4(8):778-86.
Sun Y, Zeng Y, Zhu Y, Feng F, Xu W, Wu C, Xing B, Zhang W, Wu P, Cui L, Wang R, Li F, Chen X, Zhu Z.
434
Structural and functional photoacoustic molecular tomography aided by emerging contrast agents.
Chem Soc Rev. 2014 Sep 22;43(20):7132-70.
Nie L, Chen X.
433
Photostimulable near-infrared persistent luminescent nanoprobes for ultrasensitive and longitudinal deep-tissue bio-imaging.
Theranostics. 2014 Aug 24;4(11):1112-22.
Chuang YJ, Zhen Z, Zhang F, Liu F, Mishra JP, Tang W, Chen H, Huang X, Wang L, Chen X, Xie J, Pan Z.
432
[18F]DPA-714 PET Imaging of AMD3100 Treatment in a Mouse Model of Stroke
Mol Pharm, 2014 Oct 6;11(10):3463-70.
Wang Y, Yue X, Kiesewetter DO, Lu J, Niu G, Teng G, Chen X
431
Color Tunable Gd-Zn-Cu-In-S/ZnS Quantum Dots for Dual Modality Magnetic Resonance and Fluorescence Imaging
Nano Res, 2014; 7(11):1581-1591.
Guo W, Yang W, Wang Y, Sun X, Liu Z, Zhang B, Chang J, Chen X
430
Surface Functionalization of Chemically Reduced Graphene Oxide for Targeted Photodynamic Therapy
J Biomed Nanotechnol, 2015;11:117-125
Huang P, Wang S, Wang X, Shen G, Lin J, Wang Z, Guo S, Cui D, Yang M, Chen X
429
Glucose Oxidase-Catalyzed Growth of Gold Nanoparticles Enables Quantitative Detection of Attomolar Cancer Biomarkers.
Anal Chem. 2014; 86(12):5800-6.
Liu D, Yang J, Wang HF, Wang Z, Huang X, Wang Z, Niu G, Hight Walker AR, Chen X.
428
Stability enhanced polyelectrolyte-coated gold nanorod-photosensitizer complexes for high/low power density photodynamic therapy.
Biomaterials. 2014 Aug;35(25):7058-67.
Shi Z, Ren W, Gong A, Zhao X, Zou Y, Brown EM, Chen X, Wu A.
427
Triphase interface synthesis of plasmonic gold bellflowers as near-infrared light mediated acoustic and thermal theranostics.
J Am Chem Soc. 2014 Jun 11;136(23):8307-13.
Huang P, Rong P, Lin J, Li W, Yan X, Zhang MG, Nie L, Niu G, Lu J, Wang W, Chen X.
426
Tumor Vasculature Targeted Photodynamic Therapy for Enhanced Delivery of Nanoparticles.
ACS Nano. 2014;8(6):6004-13.
Zhen Z, Tang W, Chuang YJ, Todd T, Zhang W, Lin X, Niu G, Liu G, Wang L, Pan Z, Chen X, Xie J.
425
One-Pot Two-Step Radiosynthesis of a New 18F-Labeled Thiol Reactive Prosthetic Group and Its Conjugate for Insulinoma Imaging
Mol Pharm, 2014;11(11):3875-84.
Yue X, Yan Y, Wu X, Niu G, Ma Y, Jacobson O, Shen B, Kiesewetter DO, Chen X
424
Multifunctional Fe3O4@Polydopamine Core-Shell Nanocomposites for Intracellular mRNA Detection and Imaging-Guided Photothermal Therapy
ACS Nano. 2014; 8(4):3876-83.
Lin LS, Cong ZX, Cao JB, Ke KM, Peng QL, Gao J, Yang HH, Liu G, Chen X.
423
A versatile RNAi nanoplatforms for systemic delivery of RNAis
ACS Nano, 2014; 8(5):4559-70.
Choi KY, Silvestre OF, Huang X, Howard GP, Hida N, Jin AJ, Carvajal N, Lee SW, Hong JI, Chen X.
422
Facile Synthesis of Pentacle Au-Cu Alloy Nanocrystals and their Plasmonic and Catalytic Properties
Nat Comm, 2014 Jul 7;5:4327.
He R, Wang YC, Wang X, Wang Z, Liu G, Zhou W, Wen L, Li Q, Wang X, Chen X, Zeng J, Hou JG
421
Targeted Therapeutic Nanotubes Influence the Viscoelasticity of Cancer Cells to Overcome Drug Resistance
ACS Nano, 2014; 8(5):4177-89.
Bhirde AA, Chikkaveeraiah BV, Srivatsan A, Niu G, Jin AJ, Kapoor A, Wang Z, Patel S, Patel V, Gorbach AM, Leapman RD, Gutkind JS, Hight Walker AR, Chen X
420
In Vivo Labeling of Serum Albumin for Positron Emission Tomography
J Nucl Med, 2014;55(7):1150-6.
Niu G, Lang L, Kiesewetter DO, Sun Z, Guo N, Guo J, Wu C, Ma Y, Chen X
419
Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes
Nat Comm, 2014;5:5799.
Yong R, Yang C, Lu J, Wang H, Schlaff C, Tandle A, Graves C, Elkahloun A, Chen X, Zhuang Z, Lonser R
418
Design Considerations of Iron-based Nanoclusters for Non-invasive Tracking of Mesenchymal Stem Cell Homing
ACS Nano, 2014; 8(5):4403-14.
Huang X, Zhang F, Wang Y, Sun X, Choi KY, Liu D, Choi JS, Shin TH, Cheon J, Niu G, Chen X
417
A symmetrical fluorous dendron-cyanine dye conjugated bimodal nanoprobe for quantitative 19F MRI and NIR fluorescence bioimaging
Adv Healthcare Mater, 2014;3(8):1326-33.
Wang Z, Yue X, Wang Y, Qian C, Huang P, Lizak M, Niu G, Wang F, Rong P, Kiesewetter DO, Ma Y, Chen X
416
Carbon dots based two-photon visible nanocarriers for safe and highly efficient delivery of siRNA and DNA
Adv Healthc Mater. 2014; 3(8):1203-9. (back cover)
Wang L, Wang X, Bhirde A, Cao J, Zeng Y, Huang X, Sun Y, Liu G, Chen X
415
Stability analysis of glutamic acid linked peptides coupled to NOTA through different chemical linkages
Mol Pharm, 2014;11(11):3867-74.
Lang L, Ma Y, Kisewetter DO, Chen X
414
A Novel Cyclic HSV1-TK Reporter Probe for Real-Time Apoptosis Imaging
Proc Natl Acad Sci U S A. 2014;111(14):5165-70.
Wang F, Hida N, Kiesewetter DO, Yang K, Wang Z, Rong P, Liang J, Tian J, Niu G, Chen X
413
Evaluation of synovial angiogenesis in patients with rheumatoid arthritis using 68Ga-PRGD2 PET/CT: a prospective proof-of-concept cohort study
Ann Rheum Dis 2014;73(6):1269-72
Zhu Z, Yin Y, Zheng K, Li F,Chen X, Zhang F, Zhang Y.
412
Dual imaging-guided photothermal/photodynamic therapy using micelles
Biomaterials, 2014 May;35(16):4656-66.
Guo M, Mao H, Li Y, Zhu A, He H, Yang H, Wang Y, Tian X, Ge C, Peng Q, Wang X, Yang X, Chen X, Liu G, Chen H
411
Propranolol Inhibits Glucose Metabolism and 18F-FDG Uptake of Breast Cancer Through Posttranscriptional Downregulation of Hexokinase-2
J Nucl Med. 2014; 55(3):439-45.
Kang F, Ma W, Ma X, Shao Y, Yang W, Chen X, Li L, Wang J.
410
PET imaging of neuroinflammation in a rat traumatic brain injury model with radiolabeled TSPO ligand DPA-714
Eur J Nucl Med Mol Imaging, 2014; 41(7):1440-9.
Wang Y, Yue X, Kisewetter DO, Niu G, Teng G, Chen X
409
Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics
Chem Rev, 2014; 114(10):5161-214.
Chen G, Qiu H, Prasad PN, Chen X
408
A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo.
Nat Protoc, 2014;9(8):1900-15.
Choi KY, Huang X, Swierczewska M, Lee SW, Hong JI, Lee S, Chen X
407
Comparison of Three Dimeric 18F-AlF-NOTA-RGD Tracers
Mol Imaging Biol, 2014 Apr;16(2):274-83.
Guo J, Lang L, Hu S, Guo N, Zhu L, Sun Z, Ma Y, Kiesewetter DO, Niu G, Xie Q, Chen X
406
18F-Alfatide and 18F-FDG Dual Tracer Dynamic PET for Parametric, Early Prediction of Tumor Response to Therapy
J Nucl Med, 2014; 55(1):154-60.
Guo J, Guo N, Lang L, Kiesewetter DO, Xie Q, Li Q, Eden HS, Niu G, Chen X
405
Multimodality Imaging of Tumor Angiogenesis in Breast Cancer Experimental Lung Metastasis
Mol Pharm, 2012; 9 (8), 2339-49.
Hong H, Zhang Y, Severin GW, Yang Y, Engle JW, Niu G, Nathanson AJ, Chen X, Leigh BR, Barnhart TE, Cai W
404
The genotype-dependent influence of functionalized multiwalled carbon nanotubes on fetal development
Biomaterials, 2014;35(2):856-65.
Huang X, Zhang F, Sun X, Choi KY, Niu G, Zhang G, Guo J, Lee S, Chen X
403
Spatial Vascular Volume Fraction Imaging for Quantitative Assessment of Angiogenesis
Mol Imaging Biol, 2014; 16(3):362-71.
Liu J, Fan W, Liu M, Lin X, Wang Y, Wang F, Chen X, Cao F, Liang J
402
In vivo volumetric molecular photoacoustic angiography and therapeutic monitoring with targeted plasmonic nanostars
Small, 2014; 10(8):1585-93. (Cover feature)
Nie L, Wang S, Wang X, Rong P, Ma Y, Liu G, Huang P, Lu G, Chen X
401
Palladium nanosheets as highly stable and effective contrast agents for in vivo photoacoustic molecular imaging
Nanoscale. 2014 Jan 16;6(3):1271-6.
Nie L, Chen M, Sun X, Rong P, Zheng N, Chen X.
400
Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy
Theranostics, 2014; 4(3): 229-239.
Rong P, Yang K, Srivatsan A, Kiesewetter DO, Yue X, Wang F, Nie L, Bhirde A, Wang Z, Liu Z, Niu G, Wang W, Chen X
399
NIR-light-induced surface-enhanced Raman scattering for detection and photothermal/photodynamic therapy of cancer cells using methylene blue-embedded gold nanorod@SiO2 nanocomposites
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From protein-protein interaction to therapy response: molecular imaging of heat shock proteins
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Noninvasive visualization of microRNA by bioluminescence imaging
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The role of molecular imaging in drug delivery
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Monitoring therapeutic response of human ovarian cancer to 17-DMAG by noninvasive PET imaging with 64Cu-DOTA-trastuzumab
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Production, modification and bio-applications of magnetic nanoparticles gestated by magnetotactic bacteria
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Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis
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Chapter 7. Molecular imaging of tumor vasculature
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Molecular Imaging of the HER-Kinase Axis in cancer
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Imaging of integrins as biomarkers for tumor angiogenesis
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Multimodality imaging of IL-18--binding protein-Fc therapy of experimental lung metastasis
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Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide-paclitaxel conjugate in mice with breast cancer
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Semiautomated radiosynthesis and biological evaluation of [18F]FEAU: a novel PET imaging agent for HSV1-tk/sr39tk reporter gene expression
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Carbon nanotubes as photoacoustic molecular imaging agents in living mice
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Short hairpin RNA interference therapy for ischemic heart disease
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Advances in anatomical, functional and molecular imaging of angiogenesis
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Molecular imaging as the main part of our decision-making and treatment strategies in stroke
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Effects of targeting moiety, linker, bifunctional chelator, and molecular charge on biological properties of 64Cu-labeled triphenylphosphonium cations
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Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent
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The synthesis of 18F-FDS and its potential application in molecular imaging
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18F-labeled BBN-RGD heterodimer for prostate cancer imaging
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Drug delivery with carbon nanotubes for in vivo cancer treatment
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Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy
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Integrin αvβ3 targeted cancer therapy
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Non-invasive PET imaging of EGFR degradation induced by heat shock protein 90 inhibitor
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Molecular imaging of human epidermal growth factor receptor 2 (HER-2) expression
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Has molecular and cellular imaging enhanced drug discovery and drug development?
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Delayed postconditioning protects against focal ischemic brain injury in rats
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Imaging of VEGF receptor in a rat myocardial infarction model using PET
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Molecular imaging for Alzheimer’s disease
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Synthesis of a potent and selective 18F-labeled delta-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for positron emission tomography imaging
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The temporal correlation of dynamic contrast-enhanced magnetic resonance imaging with tumor angiogenesis in a murine glioblastoma model
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Imaging mesenchymal stem cell migration and the implications for stem cell-based cancer therapies
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Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography
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Ultrasmall c(RGDyK)-coated Fe3O4 nanoparticles and their specific targeting to integrin αvβ3-rich tumor cells
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PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody
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In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin avβ3
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In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery
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Combination of integrin siRNA and irradiation for breast cancer therapy
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41
MicroPET imaging of breast cancer av-integrin expression with 64Cu-labeled dimeric RGD peptides
Mol Imaging Biol, 2004;6(5):350-9.
Chen X, Liu S, Hou Y, Tohme M, Park R, Bading JR, Conti PS.
40
microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3]bombesin in human prostate adenocarcinoma xenografts
J Nucl Med, 2004;45(8):1390-7. (Cover feature)
Chen X, Park R, Hou Y, Tohme M, Shahinian AH, Bading JR, Conti PS
39
MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide
Eur J Nucl Med Mol Imaging, 2004;31(8):1081-9.
Chen X, Park R, Khankaldyyan V, Tohme M, Bading JR, Laug WE, Conti PS.
38
Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation
Nucl Med Biol, 2004;31(1):11-9.
Chen X, Park R, Shahinian AH, Bading JR, Conti PS
37
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis
Nucl Med Biol, 2004;31(2):179-89.
Chen X, Park R, Shahinian AH, Tohme M, Khankaldyyan V, Bozorgzadeh MH, Bading JR, Moats R, Laug WE, Conti PS
36
MicroPET and autoradiographic imaging of breast cancer av-integrin expression using 18F- and 64Cu-labeled RGD peptide
Bioconjug Chem, 2004;15(1):41-9.
Chen X, Park R, Tohme M, Bading JR, Conti PS
35
MicroPET imaging of avβ3 integrin expression with 18F-labeled dimeric RGD peptide
Mol Imaging, 2004;3(2):96-104.
Chen X, Tohme M, Park R, Hou Y, Bading JR, Conti PS.
34
Unusual magnetic properties of one-dimensional molecule-based magnets associated with a structural phase transition
Inorg Chem 2002;41:5686-92.
Ren X, Meng Q, Song Y, Lu C, Hu C, Chen X
33
Unusual magnetic property associated with dimerization within a nickel tetramer
Inorg Chem 2002;41:5931-3.
Ren, X, Meng Q, Song Y, Hu C, Lu C, Chen X, Xue Z
32
Synthesis, crystal structure and magnetic properties of [RbzPy] [Fe(mnt)2] complexes ([RbzPy]+ = 1-(4’-R-benzyl)pyridinium, R = NO2 and Cl; mnt2 = maleonitriledithiolate)
Transition Met Chem 2002;27:394-7.
Ren X, Wu P, Zhang W, Meng Q, Chen X
31
Spectroscopic and structural studies of complexes of the fac-[Re(N∩N)(CO)3L]n+ type (N∩N=2-(2-pyridyl)benzothiazole; L=Cl, Br, CF3SO3−, CH3CN)
Inorg Chim Acta 2001;314:91-6.
Chen X, Femia FJ, Babich, JW, Zubieta J
30
Synthesis, characterization and crystal structures of mono-, di- and trinuclear rhenium(I) tricarbonyl complexes with 2,3,5,6-tetra(2-pyridyl)pyrazine
Inorg Chim Acta 2001;315:66-72
Chen X, Femia FJ, Babich, JW, Zubieta J
29
Synthesis and structural characterization of rhenium(I) tricarbonyl complexes with the bidentate ligands o-(diphenylphosphino)benzaldehyde (P∩O) and o-[(diphenylphosphino)benzylidene]analine (P∩N)
Inorg Chim Acta 2001;315:147-52
Chen X, Femia FJ, Babich, JW, Zubieta J
28
Schiff base chemistry of the rhenium(V)-oxo core with “3+2” ligand donor sets
Inorg Chim Acta 2001;316:33-40
Chen X, Femia FJ, Babich, JW, Zubieta J
27
Rhenium(I) carbonyl complexes of 2,4,6-tris(2-pyridyl)-1,3,5-triazine (TPT). Rhenium (I)-promoted methoxylation of the triazine ring carbon atom in dinuclear rhenium complexes
Inorg Chem 2001;40:2769-77.
Chen X, Femia FJ, Babich, JW, Zubieta J
26
Synthesis and characterization of a '3+2' {Re(V)O}3+ core complex carrying the ONS/PO donor atom set
Inorg Chim Acta 2001;316:145-8.
Femia FJ, Chen X, Babich JW, Zubieta J
25
Oxorhenium(V) complexes containing tridentate Schiff-base and monothiol coligands
Inorg Chim Acta 2000;300-302:517-524.
Femia, FJ, Chen X, Babich, JW, Zubieta J
24
Synthesis and characterization of complexes of the {ReO}3+ core with SNS and S donor ligands
Inorg Chim Acta 2000;306:30-37.
Femia, FJ, Chen X, Maresca KP, Shoup, TM, Babich, JW, Zubieta J
23
Investigations of the {ReO}3+ core: A “2+2” complex from bidentate and potentially trident ligands: [ReO(η2-HOC6H4-2-CH2NC6H4S)(η2-SC5H4N)(PPh3)]
Inorg Chim Acta 2000;306:38-41.
Chen X, Femia FJ, Babich, JW, Zubieta J
22
Structural characterizations of an Re(IV) complex [ReCl4(OPPh3)2] and of an imino species [ReOCl2(PPh3)(2-OC6H4-2-CH=NH)] prepared from the reaction of [ReOCl3(PPh3)2] with salicylaldoxime
Inorg Chim Acta 2000;306:112-5.
Chen X, Femia FJ, Babich, JW, Zubieta J.
21
Synthesis and characterization of oxorhenium(V)–‘3+1’ mixed thiolate [SNS]/[S] and [ONS]/[S] complexes. Crystal and molecular structures of [ReO(η3-SCH2C5H3NCH2S)(η1-C6H4Br-4-S)], [ReO(η3-SCH2C5H3NCH2O)(η1-C6H4X-4-S)] (X=Cl, OMe), [ReO(η3-SCH2C5H3NCH2O)(η1-C6H4OCH3-4-CH2S)] and [ReO(η3-SCH2C5H3NCH2S)(η1-C5H4NH-2-S)][Cl]
Inorg Chim Acta 2000;307:88-96.
Chen X, Femia FJ, Babich, JW, Zubieta J.
20
Schiff base chemistry of the {ReO}3+ core: structural characterization of the unusual “3+2” complex [ReO(η3-OC6H4–CH=NC6H4-2-S)(η2-OC6H4C=NC6H4-2-S)]
Inorg Chim Acta 2000;307:149-153.
Chen X, Femia FJ, Babich, JW, Zubieta J
19
Exploring oxorhenium “3+1” mixed-ligand complexes carrying the S-benzyl-3-[(2-hydroxyphenyl)methylene]dithiocarbazate [ONS]/monothiol [S] donor set: synthesis and characterization
Inorg Chim Acta 2000;307:154-9.
Chen X, Femia FJ, Babich, JW, Zubieta J.
18
Synthesis and crystal and molecular structure of a tetranuclear cluster based on the rhenium(III)-bisorganohydrazino core: [Re(HNNC4H3N2)(NNC4H3N2)(OCH3)2]4
Inorg Chim Acta 2000;307:160-3.
Femia, FJ, Chen X, Maresca KP, Babich, JW, Zubieta J.
17
The syntheses and structures of “3+2” and “2+2+1” oxorhenium mixed-ligand complexes employing 8-hydroxy-5-nitroquinoline as the bidentate N,O donor ligand
Inorg Chim Acta 2000;308:80-90.
Chen X, Femia FJ, Babich, JW, Zubieta J.
16
Syntheses and structural characterization of rhenium-bis-hydrazinopyrimidine core complexes with thiolate and Schiff base coligands
Inorg Chim Acta 2000;310:210-6.
Femia, FJ, Chen X, Maresca KP, Babich, JW, Zubieta J
15
An unexpected “4+2” [N3S]/[NS] rhenium(IV) complex formed upon cleavage of a Re(V) imido bond
Inorg Chim Acta 2000;310:237-41.
Chen X, Femia FJ, Babich, JW, Zubieta J
14
Synthesis, structure, spectral and magnetic properties of a dinuclear copper(II)/nickel(II) complex bridged by glyoximate groups
Polyhedron 1999;18(15):2035-9.
Zhan S, Hu C, Chen X, Meng Q, Lu C, Wang G, Zheng P.
13
Synthesis, studies and molecular structure of trinuclear cyanide-bridged copper-iron complexes
Inorg Chim Acta 1999;292(2):157-62.
Zhan S, Chen X, Vij A, Guo D, Meng Q.
12
Synthesizing and dispersing silver nanoparticles in a water-in-supercritical carbon dioxide microemulsion
J Am Chem Soc 1999;121:2631-2.
Ji M, Chen X, Wai CM, Fulton JL.
11
Selective extraction of strontium by supercritical fluid carbon dioxide
Chem Commun (Cambridge) 1999:2533-2534.
Wai CM, Kulyako Y, Yak, H-K, Chen X, Lee S-J.
10
Monofunctionalization of calix[4]arene tetracarboxylic acid at the upper rim with isothiocyanate group: first bifunctional chelating agent for alpha-emitter Ac-225
Synlett 1999;11:1784-6.
Chen X, Ji M, Fisher DR, Wai CM.
9
Ionizable calixarene-crown ethers with high selectivity for radium over lighter alkaline earth metal ions
Inorg Chem 1999;38(23):5449-52.
Chen X, Ji M, Fisher DR, Wai CM
8
Carboxylate-derived calixarenes with high selectivity for actinium-225
Chem Commun (Cambridge) 1998:377-8.
Chen X, Ji M, Fisher DR, Wai CM.
7
Chemical reactions in supercritical carbon dioxide
J Chem Edu 1998;75:641-5.
Wai CM, Hunt F, Ji M, Chen X.
6
Synthesis, electrochemical and magnetic properties of Cu3 complexes of a series of new compartmental trinucleating ligands H4L
J Chem Soc Dalton Trans. 1997:245-50.
Chen X, Zhan S, Hu C, Meng Q, Liu Y.
5
Binickel(II) complex of a new asymmetrical acyclic ligand: the X-ray crystal structure of [Ni2L](ClO4)2 reveals alternating square-planar and octahedral nickel ions
Inorg Chim Acta 1997;260(1):95-8.
Chen X, Zhan S, Hu C, Meng Q, Shun J.
4
Synthesis, characterization and electrochemical properties of cyanide-bridged cobalt(III)/iron(II) complexes
Syn React Inorg Met-Org Chem 1996;26(2):277-84.
Zhang S, Chen X, Meng Q, Xie W.
3
Synthesis and properties of cyano-bridged nickel(II)-iron(III) complexes
Transition Met Chem (London) 1996;21(2):181-3.
Zhan S, Chen X, Meng Q.
2
Synthesis and Spectroscopic Studies of Trinuclear Uranyl Complexes with Compartmental Ligands H4L Derived From 2,6-Dipicolinoyl-hydrazine and 4-Acyl-1-Phenyl-3-Methyl-Pyrazolones-5 (Where Acyl = Benzoyl, Acetyl, iso-Butyryl or iso-Valeroyl)
Transition Met Chem (London) 1996;21(4):345-8.
Chen X, Zhan S, Meng Q.
1
Kinetic study of nucleophilic substitution reactions of N-methylimidazole with hemin chloride
J Inorg Chem 1995;11(2):192-7.
Chen X, Zhang X, Meng Q, Sweigart DA.