Publications in 2024
1113
The Landscape of Smart Biomaterial-Based Hydrogen Therapy.
Adv Sci (Weinh). 2024 Aug 21:e2401310.
Xu M, Wu G, You Q, Chen X.
1112
Carrier-Free Nanodrugs: From Bench to Bedside
ACS Nano. 2024 Aug 20. doi: 10.1021/acsnano.4c09027.
Fang F, Chen X.
1111
Disulfidoptosis as a Novel Mechanism of Neuronal Death: Insights from Creutzfeldt-Jakob Disease.
World Neurosurg. 2024 Aug 17:S1878-8750(24)01439-6. doi: 10.1016/j.wneu.2024.08.070.
Wu Q, Liu SP, Liu C, Chen X, Zhou H, Zhao H.
1110
Development of [177Lu]Lu-LNC1010 for peptide receptor radionuclide therapy of nasopharyngeal carcinoma
Eur J Nucl Med Mol Imaging. 2024 Aug 15. doi: 10.1007/s00259-024-06874-9.
Chen J, Pang Y, Liao X, Zhou Y, Luo Q, Wu H, Zuo C, Zhang J, Lin Q, Chen X, Zhao L, Chen H.
1109
Lung ultrasound score evaluation of the effect of pressure-controlled ventilation volume-guaranteed on patients undergoing laparoscopic-assisted radical gastrectomy.
World J Gastrointest Surg. 2024 Jun 27;16(6):1717-1725.
Tan J, Bao CM, Chen XY.
1108
Metal-polyphenol self-assembled nanodots for NIR-II fluorescence imaging-guided chemodynamic/photodynamic therapy-amplified ferroptosis.
Acta Biomater. 2024 Jul 23:S1742-7061(24)00388-X.
Zhu Y, Ding C, Fang W, Li T, Yan L, Tian Y, Huang W, Wei P, Ma J, Lin X, Huang W, Lin Y, Zou J, Chen X.
1107
Targeted Radionuclide Therapy in Glioblastoma.
ACS Appl Mater Interfaces. 2024 Aug 7;16(31):40391-40410.
Zhao X, Jakobsson V, Tao Y, Zhao T, Wang J, Khong PL, Chen X, Zhang J.
1106
Precise Identification of Glioblastoma Micro-Infiltration at Cellular Resolution by Raman Spectroscopy
Adv Sci (Weinh). 2024 Jul 31:e2401014.
Zhu L, Li J, Pan J, Wu N, Xu Q, Zhou QQ, Wang Q, Han D, Wang Z, Xu Q, Liu X, Guo J, Wang J, Zhang Z, Wang Y, Cai H, Li Y, Pan H, Zhang L, Chen X, Lu G.
1105
A Dual-Targeting, Multi-Faceted Biocompatible Nanodrug Optimizes the Microenvironment to Ameliorate Abdominal Aortic Aneurysm.
Adv Mater. 2024 Jun 24:e2405761.
Mo F, Wang C, Li S, Li Z, Xiao C, Zhang Y, Hu C, Wang E, Lin P, Yuan T, Zuo Z, Fu W, Chen X, Ren L, Wang L.
1104
Multifaceted Carbonized Metal-Organic Frameworks Synergize with Immune Checkpoint Inhibitors for Precision and Augmented Cuproptosis Cancer Therapy
ACS Nano. 2024 Jun 28. doi: 10.1021/acsnano.4c04022.
Zhao C, Tang X, Chen X, Jiang Z.
1103
Engineering of a DNA/γPNA Hybrid Nanoreporter for ctDNA Mutation Detection via γPNA Urinalysis
Adv Sci (Weinh). 2024 Jul 3:e2310225
Xiang Z, Lu J, Ming Y, Guo W, Chen X, Sun W.
1102
Antitumor efficacy and potential mechanism of FAP-targeted radioligand therapy combined with immune checkpoint blockade.
Signal Transduct Target Ther. 2024 Jun 3;9(1):142.
Zhao L, Pang Y, Zhou Y, Chen J, Fu H, Guo W, Xu W, Xue X, Su G, Sun L, Wu H, Zhang J, Wang Z, Lin Q, Chen X, Chen H.
1101
Manipulating calcium homeostasis with nanoplatforms for enhanced cancer therapy.
Exploration (Beijing). 2023 Oct 10;4(1):20230019. doi: 10.1002/EXP.20230019.
Feng Y, Wang J, Cao J, Cao F, Chen X.
1100
Neuroprotective effects of anti-TRAIL-ICG nanoagent and its multimodal imaging evaluation in cerebral ischemia-reperfusion injury.
Mater Today Bio. 2024 May 22;26:101094. doi: 10.1016/j.mtbio.2024.101094.
Yang Q, Ye W, Luo D, Xing J, Xiao Q, Wu H, Yao Y, Wang G, Yang L, Guo D, Wang K, He Y, Ye X, Zhang J, Jin Z, Fan Z, Wen X, Mao J, Chen X, Zhao Q.
1099
Diagnostic performance and clinical impact of 18F-AlF-NOTA-octreotide in a large cohort of patients with neuroendocrine neoplasms: A prospective single-center study.
Theranostics. 2024 May 19;14(8):3213-3220.
Hou G, Cheng X, Yang Y, Zhao D, Wang G, Zhao H, Zheng R, Wang X, Chen X, Chi Y, Zhang J.
1098
"AquaF" Building Blocks for Water-Compatible SN2 18F-Fluorination of Small-Molecule Radiotracers.
J Am Chem Soc. 2024 Jun 13. doi: 10.1021/jacs.4c05854.
Mou Z, Zhu Y, Zhang L, Ma M, Li Z, Guo Y, Zheng J, Zhao Z, Zhang K, Chen X, Li Z.
1097
Engineered Antibodies as Cancer Radiotheranostics.
Adv Sci (Weinh). 2024 Jun 14:e2402361. doi: 10.1002/advs.202402361.
Wei Z, Li B, Wen X, Jakobsson V, Liu P, Chen X, Zhang J.
1096
Nanomaterial-Based Strategies for Attenuating T-Cell-Mediated Immunodepression in Stroke Patients: Advancing Research Perspectives
Int J Nanomedicine. 2024 Jun 12;19:5793-5812.
Wang Y, Liu C, Ren Y, Song J, Fan K, Gao L, Ji X, Chen X, Zhao H.
1095
Hairpin DNA-Based Nanomaterials for Tumor Targeting and Synergistic Therapy
Int J Nanomedicine. 2024 Jun 12;19:5781-5792.
Shan L, Li Y, Ma Y, Yang Y, Wang J, Peng L, Wang W, Zhao F, Li W, Chen X
1094
Wake biofilm up to enhance suicidal uptake of gallium for chronic lung infection treatment.
Biomaterials. 2024 May 17;310:122619. doi: 10.1016/j.biomaterials.2024.122619.
He J, Lin X, Zhang D, Hu H, Chen X, Xu F, Zhou M.
1093
olyprodrug nanomedicine for chemiexcitation-triggered self-augmented cancer chemotherapy and gas therapy.
Biomaterials. 2024 Sep;309:122606. doi: 10.1016/j.biomaterials.2024.122606.
Wang Q, Zhang C, Zhao Y, Jin Y, Zhou S, Qin J, Zhang W, Hu Y, Chen X, Yang K.
1092
Albumin-seeking dyes with adjustable assemblies in situ enable programmable imaging windows and targeting tumor imaging.
Theranostics. 2024 Apr 15;14(7):2675-2686
Du Y, Xu J, Han T, Jiang Z, Zhang Y, Li J, Chen X, Zhu S.
1091
Prostate-specific membrane antigen-targeted surgery in prostate cancer: Accurate identification, real-time diagnosis, and precise resection
Theranostics. 2024 Apr 22;14(7):2736-2756
Jiao J, Zhang J, Wen W, Qin W, Chen X.
1090
Immunological nanomaterials to combat cancer metastasis.
Chem Soc Rev. 2024 May 15. doi: 10.1039/d2cs00968d
Pan Y, Cheng J, Zhu Y, Zhang J, Fan W, Chen X.
1089
Diagnostic Performance of [18F]AlF-Thretide PET/CT in Patients with Newly Diagnosed Prostate Cancer Using Histopathology as Reference Standard
J Nucl Med. 2024 May 9:jnumed.123.266940. doi: 10.2967/jnumed.123.266940.
Zang J, Yang Y, Chen S, Wang C, Chen S, Hu S, Cai H, Li X, Xu N, Chen X, Zhang J, Miao W
1088
Carboxylesterase Activatable Molecular Probe for Personalized Treatment Guidance by Analyte-Induced Molecular Transformation
Angew Chem Int Ed Engl. 2024 May 10:e202404093. doi: 10.1002/anie.202404093
Li B, Liu H, Zhao M, Zhang X, Huang P, Chen X, Lin J
1087
Partial root-zone drying combined with nitrogen treatments mitigates drought responses in rice.
Front Plant Sci. 2024 Apr 15;15:1381491.
Zhao M, Gao Z, Kuang C, Chen X.
1086
A Guanidinobenzol-Rich Polymer Overcoming Cascade Delivery Barriers for CRISPR-Cas9 Genome Editing.
Nano Lett. 2024 Apr 29. doi: 10.1021/acs.nanolett.4c00533.
Liang S, Ma N, Li X, Yun K, Meng QF, Ma K, Yue L, Rao L, Chen X, Wang Z.
1085
Design and Characterization of a New Formulation for the Delivery of COVID-19-mRNA Vaccine to the Nasal Mucosa.
Vaccines (Basel). 2024 Apr 12;12(4):409.
Altay Benetti A, Tan EYZ, Chang ZW, Bae KH, Thwin MT, Muthuramalingam RPK, Liao KC, Wan Y, Ng LFP, Renia L, Liu J, Chen X, Yang YY, White KP, Pastorin G.
1084
Double-Layered Hollow Mesoporous Cuprous Oxide Nanoparticles for Double Drug Sequential Therapy of Tumors.
Adv Mater. 2024 Apr 26:e2313212.
Li Z, Yang J, Ren B, Fan Q, Huang L, Guo S, Zhou R, Chen S, Feng J, Yan C, Chen X, Shen Z.
1083
Expression of concern: Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery.
Nanoscale. 2024 Apr 25. doi: 10.1039/d4nr90085e.
Wang X, Zhou Z, Wang Z, Xue Y, Zeng Y, Gao J, Zhu L, Zhang X, Liu G, Chen X.
1082
A mesoporous superparamagnetic iron oxide nanoparticle as a generic drug delivery system for tumor ferroptosis therapy.
J Nanobiotechnology. 2024 Apr 24;22(1):204.
Yang J, Xiong W, Huang L, Li Z, Fan Q, Hu F, Duan X, Fan J, Li B, Feng J, Xu Y, Chen X, Shen Z.
1081
Programming peptide-oligonucleotide nano-assembly for engineering of neoantigen vaccine with potent immunogenicity.
Theranostics. 2024 Mar 17;14(6):2290-2303
Xiang Z, Lu J, Rao S, Fu C, Yao Y, Yi Y, Ming Y, Sun W, Guo W, Chen X.
1080
Theranostics - a sure cure for cancer after 100 years?
Theranostics. 2024 Mar 31;14(6):2464-2488. doi: 10.7150/thno.96675
Song Y, Zou J, Castellanos EA, Matsuura N, Ronald JA, Shuhendler A, Weber WA, Gilad AA, Müller C, Witney TH, Chen X.
1079
Spatiotemporal Concurrent PARP Inhibitor Sensitization based on Radiation-Responsive Nanovesicles for Lung Cancer Chemoradiotherapy.
Adv Healthc Mater. 2024 Apr 10:e2400908.
Kang F, Niu M, Zhou Z, Zhang M, Xiong H, Zeng F, Wang J, Chen X.
1078
A DNA origami device spatially controls CD95 signalling to induce immune tolerance in rheumatoid arthritis
Nat. Mater. (2024). DOI:10.1038/s41563-024-01865-5
Ling Li, Jue Yin, Wen Ma, Longguang Tang, Jianhua Zou, Linzi Yang, Ting Du, Yi Zhao, Lianhui Wang, Zhen Yang, Chunhai Fan, Jie Chao & Xiaoyuan Chen
1077
Carrier-Free Self-Assembly Nano-Sonosensitizers for Sonodynamic-Amplified Cuproptosis-Ferroptosis in Glioblastoma Therapy.
Adv Sci (Weinh). 2024 Apr 6:e2402516. doi: 10.1002/advs.202402516
Zhu Y, Niu X, Ding C, Lin Y, Fang W, Yan L, Cheng J, Zou J, Tian Y, Huang W, Huang W, Pan Y, Wu T, Chen X, Kang D
1076
Clinical translation of a novel FAPI dimer [68Ga]Ga-LNC1013.
Eur J Nucl Med Mol Imaging. 2024 Apr 2. doi: 10.1007/s00259-024-06703-z
Tan Y, Li J, Zhao T, Zhou M, Liu K, Xiang S, Tang Y, Jakobsson V, Xu P, Chen X, Zhang J.
1075
Narrow Bandgap Schottky Heterojunction Sonosensitizer with High Electron-Hole Separation Boosted Sonodynamic Therapy in Bladder Cancer
Adv Mater. 2024 Mar 28:e2401252
Li G, Wu S, Liu J, Wang K, Chen X, Liu H.
1074
Neutrophil Targeting Platform Reduces Neutrophil Extracellular Traps for Improved Traumatic Brain Injury and Stroke Theranostics.
Adv Sci (Weinh). 2024 Mar 23:e2308719. doi: 10.1002/advs.202308719
Mu Q, Yao K, Syeda MZ, Wan J, Cheng Q, You Z, Sun R, Zhang Y, Zhang H, Lu Y, Luo Z, Li Y, Liu F, Liu H, Zou X, Zhu Y, Peng K, Huang C, Chen X, Tang L.
1073
Neutrophil Membrane-Camouflaged Polyprodrug Nanomedicine for Inflammation Suppression in Ischemic Stroke Therapy
Adv Mater. 2024 Mar 22:e2311803. doi: 10.1002/adma.202311803
Zhao Y, Li Q, Niu J, Guo E, Zhao C, Zhang J, Liu X, Wang L, Rao L, Chen X, Yang K.
1072
Targeting Strategies for Site-Specific mRNA Delivery
Bioconjug Chem. 2024 Mar 16. doi: 10.1021/acs.bioconjchem.4c00038
Di J, Huang P, Chen X
1071
Coassembly Nanomedicine Mediated by Intermolecular Interactions Between Methotrexate and Baricitinib for Improved Rheumatoid Arthritis Treatment.
ACS Nano. 2024 Mar 4. doi: 10.1021/acsnano.3c12692
Xiong H, Zhang H, Qin Y, Ye J, Zeng F, Xie P, Shi C, Luo C, Xu W, Yu C, Zhou Z, Chen X
1070
Nanomedicines for an Enhanced Immunogenic Cell Death-Based In Situ Cancer Vaccination Response
Acc Chem Res. 2024 Feb 28. doi: 10.1021/acs.accounts.3c00771
Zhao C, Wang C, Shan W, Wang Z, Chen X, Deng H.
1069
Self-Adjuvanting Polyguanidine Nanovaccines for Cancer Immunotherapy
ACS Nano. 2024 Feb 26. doi: 10.1021/acsnano.3c11637
Zhang X, Wang K, Zhao Z, Shan X, Wang Y, Feng Z, Li B, Luo C, Chen X, Sun J
1068
Advancing nanotechnology for neoantigen-based cancer theranostics
Chem Soc Rev. 2024 Feb 21. doi: 10.1039/d3cs00162h.
Zou J, Zhang Y, Pan Y, Mao Z, Chen X
1067
Synthesis, preclinical, and initial clinical evaluation of integrin αVβ3 and gastrin-releasing peptide receptor (GRPR) dual-targeting radiotracer [68Ga]Ga-RGD-RM26-03.
Eur J Nucl Med Mol Imaging. 2024 Feb 20. doi: 10.1007/s00259-024-06634-9.
Wen X, Wang R, Xu P, Shi M, Shang Q, Zeng X, Zeng X, Liu J, Wang X, Zhu Z, Guo Z, Chen X, Zhang J.
1066
A non-metal single atom nanozyme for cutting off the energy and reducing the power of tumors
Angew Chem Int Ed Engl. 2024 Feb 15:e202319982.
Cheng J, Li L, Jin D, Zhang Y, Yu W, Yu J, Zou J, Dai Y, Zhu Y, Liu M, Zhang M, Sun Y, Liu Y, Chen X
1065
Apoptotic Vesicular Metabolism Contributes to Organelle Assembly and Safeguards Liver Homeostasis and Regeneration
Gastroenterology. 2024 Feb 9:S0016-5085(24)00136-7.
Sui B, Wang R, Chen C, Kou X, Wu D, Fu Y, Lei F, Wang Y, Liu Y, Chen X, Xu H, Liu Y, Kang J, Liu H, Kin Kwok RT, Tang BZ, Yan H, Wang M, Xiang L, Yan X, Zhang X, Ma L, Shi S, Jin Y.
1064
AcousticRobots: Smart acoustically powered micro-/nanoswimmers for precise biomedical applications
Adv Drug Deliv Rev. 2024 Feb 6;207:115201
Wu G, Xian W, You Q, Zhang J, Chen X
1063
Redox-responsive polymer micelles co-encapsulating immune checkpoint inhibitors and chemotherapeutic agents for glioblastoma therapy
Nat Commun. 2024 Feb 6;15(1):1118
Zhang Z, Xu X, Du J, Chen X, Xue Y, Zhang J, Yang X, Chen X, Xie J, Ju S.
1062
pH/GSH dual responsive nanosystem for nitric oxide generation enhanced type I photodynamic therapy
Bioact Mater. 2024 Jan 10;34:414-421. doi: 10.1016/j.bioactmat.2023.12.023.
Zou J, Li Z, Zhu Y, Tao Y, You Q, Cao F, Wu Q, Wu M, Cheng J, Zhu J, Chen X
1061
Development and Applications of D-Amino Acid Derivatives-based Metabolic Labeling of Bacterial Peptidoglycan
Angew Chem Int Ed Engl. 2024 Jan 29:e202319400
Zheng Y, Zhu X, Jiang M, Cao F, You Q, Chen X
1060
Microalgae-Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression
Adv Mater. 2024 Jan 26:e2312275. doi: 10.1002/adma.202312275
Zhong D, Jin K, Wang R, Chen B, Zhang J, Ren C, Chen X, Lu J, Zhou M
1059
Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation
JCI Insight. 2024 Feb 22;9(4):e174097
Manoli I, Sysol JR, Head PE, Epping MW, Gavrilova O, Crocker MK, Sloan JL, Koutsoukos SA, Wang C, Ktena YP, Mendelson S, Pass AR, Zerfas PM, Hoffmann V, Vernon HJ, Fletcher LA, Reynolds JC, Tsokos MG, Stratakis CA, Voss SD, Chen KY, Brown RJ, Hamosh A, Berry GT, Chen XS, Yanovski JA, Venditti CP
1058
Mitochondria-specific near-infrared photoactivation of peroxynitrite upconversion luminescent nanogenerator for precision cancer gas therapy
Acta Pharm Sin B. 2024 Jan;14(1):378-391
Yu H, Tiemuer A, Yao X, Zuo M, Wang HY, Liu Y, Chen X
1057
A comparison of [18F]AlF- and 68Ga-labeled dual targeting heterodimer FAPI-RGD in malignant tumor: preclinical evaluation and pilot clinical PET/CT imaging
Eur J Nucl Med Mol Imaging. 2024 Jan 22. doi: 10.1007/s00259-023-06587-5
Liu N, Wan Q, Wu X, Zhao T, Jakobsson V, Yuan H, Chen X, Zhang J, Zhang W
1056
In Situ Reprogramming of Immune Cells Using Synthetic Nanomaterials
Advanced materials (Deerfield Beach, Fla.), 2024, e2310168.
Nie, S., Qin, Y., Ou, L., Chen, X., & Li, L.
1055
First-in-human validation of enzymolysis clearance strategy for decreasing renal radioactivity using modified [68Ga]Ga-HER2 Affibody.
European journal of nuclear medicine and molecular imaging, 2024, 10.1007/s00259-023-06584-8.
Zhang, M., Kang, F., Xing, T., Wang, J., Ma, T., Li, G., Quan, Z., Yang, W., Chen, X., & Wang, J.
1054
Synergistic Glutathione Depletion and STING Activation to Potentiate Dendritic Cell Maturation and Cancer Vaccine Efficacy
Angewandte Chemie (International ed. in English), 2024, e202318530.
Liu, J., Zhang, Y., Yang, B., Jia, Y., Liu, R. T., Ding, L., Shen, Z., & Chen, X.
1053
Long-term Nephrotoxicity after PRRT: Myth or Reality.
Theranostics, 2024, 14(2), 451–459
Baum, R. P., Fan, X., Jakobsson, V., Yu, F., Schuchardt, C., Chen, X., & Zhang, J.
1052
Lower-grade gliomas surgery guided by GRPR-targeting PET/NIR dual-modality image probe: a prospective and single-arm clinical trial.
Theranostics, 2024, 14(2), 819–829
Chen, L., Zhang, J., Chi, C., Che, W., Dong, G., Wang, J., Du, Y., Wang, R., Zhu, Z., Tian, J., Ji, N., Chen, X., & Li, D.
1051
LCP1 knockdown in monocyte-derived macrophages: mitigating ischemic brain injury and shaping immune cell signaling and metabolism
Theranostics, 2024, 14(1), 159–175
Wang, Y., Yin, Q., Yang, D., Jin, H., Yao, Y., Song, J., Liu, C., Nie, Y., Yin, H., Wang, W., Xu, B., Xue, L., Ji, X., Chen, X., & Zhao, H.
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