Publications in 2020
866
Resection and survival data from a clinical trial of glioblastoma multiforme-specific IRDye800-BBN fluorescence-guided surgery.
Bioeng Transl Med. 2020;6(1):e10182.
He K, Chi C, Li D, Zhang J, Niu G, Lv F, Wang J, Che W, Zhang L, Ji N, Zhu Z, Tian J, Chen X.
865
Supramolecular coordination complexes as diagnostic and therapeutic agents.
Curr Opin Chem Biol. 2020;61:19-31.
Yu G, Jiang M, Huang F, Chen X
864
Reactive Oxygen Species Activatable Heterodimeric Prodrug as Tumor-Selective Nanotheranostics.
ACS Nano. 2020; 14: 16875–16886
Jiang M, Mu J, Jacobson O, Wang Z, He L, Zhang F, Yang W, Lin Q, Zhou Z, Ma Y, Lin J, Qu J, Huang P, Chen X
863
First report of 68Ga-PRGD2 PET/MRI molecular imaging of vaso-occlusion in a patient with sickle cell disease.
BJR Case Rep. 2020;6(4):20200024.
Novelli EM, Moon CH, Pham TA, Perkins LA, Little-Ihrig L, Tavakoli S, Mason NS, Lang L, Chen X, Laymon CM, Gladwin MT, Anderson CJ.
862
Genetically engineered magnetic nanocages for cancer magneto-catalytic theranostics
Nat Commun. 2020;11(1):5421.
Zhang Y, Wang X, Chu C, Zhou Z, Chen B, Pang X, Lin G, Lin H, Guo Y, Ren E, Lv P, Shi Y, Zheng Q, Yan X, Chen X, Liu G.
861
Size-Transformable Antigen-Presenting Cell Mimicking Nanovesicles for Effective Cancer Immunotherapy
Sci Adv, 2020;6(50):eabd1631.
Yang W, Deng H, Zhu S, Lau J, Tian R, Wang S, Zhou Z, Yu G, Rao L, He L, Ma Y, Chen X
860
Targeted Scavenging of Extracellular ROS Relieves Suppressive Immunogenic Cell Death
Nat Commun, 2020;11(1):4951.
Deng H, Yang W, Zhou Z, Tian R, Lin L, Ma Y, Song J, Chen X
859
New Opportunities in Cancer Immunotherapy and Theranostics.
Acc Chem Res. 2020;53(12):2763-2764.
Chen XS, Moon JJ, Cheon J.
858
Cascade Drug Release Strategy for Enhanced Anticancer Therapy
Matter, 2021; 4: 26-53
Zhang X, Wang S, Cheng G, Yu P, Chang J, Chen X
857
Activating Macrophage-Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles
Adv Mater, 2020;32:2004853
Rao L, Zhao S-K, Wen C, Tian R, Lin L, Cai B, Sun Y, Kang F, Yang Z, He L, Mu J, Meng Q-F, Yao G, Xie N, Chen X
856
Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines
PNAS, 2020:202014352. [cover story, highlighted by the Scientist]
Rao L, Xia S, Xu W, Tian R, Yu G, Gu C, Pan P, Meng Q-F, Cai X, Qu D, Lu L, Xie Y, Jiang S, Chen X
855
Reducing false negatives in COVID-19 testing by using microneedle-based oropharyngeal swabs
Matter, 2020;3(5):1589-1600. [Cover]
Chen W, Cai B, Cheng Z, Chen F, Wang Z, Wang L, Chen X
854
Peptide Receptor Radionuclide Therapy of Late-stage Neuroendocrine Tumor Patients with Multiple Cycles of 177Lu-DOTA-EB-TATE
J Nucl Med. 2020 Aug 21:jnumed.120.248658. doi: 10.2967/jnumed.120.248658.
Liu Q, Zang J, Sui H, Ren J, Guo H, Wang H, Wang R, Jacobson O, Zhang J, Cheng Y, Zhu Z, Chen X.
853
Targeted radionuclide therapy in patient-derived xenografts using 177Lu-EB-RGD
Mol Cancer Ther. 2020; 19(10): 2034-2043.
Zhao L, Chen H, Guo Z, Fu K, Yao L, Fu L, Guo W, Wen X, Jacobson O, Zhang X, Sun L, Wu H, Lin Q, Chen X.
852
Recent Advances in Stimuli-Responsive Platforms for Cancer Immunotherapy
Acc Chem Res. 2020; 53(10): 2044-2054.
Li L, Yang Z, Chen X.
851
Cell Death Mediated by Pyroptosis Pathway with the Help of Nanotechnology: New Prospects for Cancer Therapy
Angew Chem Int Ed Engl. 2020 Sep 7. doi: 10.1002/anie.202010281.
Wu D, Wang S, Yu G, Chen X.
850
The critical size of gold nanoparticles for overcoming P-gp mediated multidrug resistance
Nanoscale. 2020;12(31):16451-16461.
Jiang Y, Wang Z, Duan W, Liu L, Si M, Chen X, Fang CJ
849
Endogenous Labile Iron Pool-Mediated Free Radical Generation for Cancer Chemodynamic Therapy
J Am Chem Soc. 2020; 142(36): 15320-15330.
Lin L, Wang S, Deng H, Yang W, Rao L, Tian R, Liu Y, Yu G, Zhou Z, Song J, Yang HH, Chen ZY, Chen X
848
Designer cell membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis
Nat Commun, 2020;11(1):4909.
Rao L, Wu L, Liu Z, Tian R, Yu G, Zhou Z, Yang K, Xiong HG, Zhang A, Yu GT, Li A, Chen H, Sun ZJ, Fu YX, Chen X
847
Nanoparticle delivery in vivo: a fresh look from an intravital imaging perspective
EBioMedicine, 2020;59:102958
Lin Q, Fathi P, Chen X
846
Cascade Reactions Catalyzed by Planar Metal Organic Framework Hybrid Architecture for Combined Cancer Therapy
Small, 2020;e2004016.
Mu J, He L, Fan W, Tang W, Wang Z, Jiang C, Zhang D, Liu Y, Deng H, Zou J, Jacobson O, Qu J, Huang P, Chen X
845
Multimodal Photoacoustic Imaging-Guided Regression of Corneal Neovascularization: A Non-Invasive and Safe Strategy
Adv Sci (Weinh). 2020;7(14):2000346. doi: 10.1002/advs.202000346.
Chu C, Yu J, Ren E, Ou S, Zhang Y, Wu Y, Wu H, Zhang Y, Zhu J, Dai Q, Wang X, Zhao Q, Li W, Liu Z, Chen X, Liu G
844
Theranostic multimodal gold nanoclusters
Nat Biomed Eng. 2020;4(7):668-669.
He G, Huang P, Chen X
843
Targeting Neutrophils for Enhanced Cancer Theranostics
Adv Mater, 2020; 32: 2002739
Tang L, Wang Z, Mu Q, Yu Z, Jacobson O, Li L, Yang W, Huang C, Kang F, Fan W, Ma Y, Wang S, Zhou Z, Chen X
842
Advanced biomimetic nanoreactor for specifically killing tumor cells through multi-enzyme cascade
Theranostics. 2020;10(14):6245-6260.
Liu W, Wu J, Ji X, Ma Y, Liu L, Zong X, Yang H, Dai J, Chen X, Xue W
841
Zwitterionic-to-cationic charge conversion polyprodrug nanomedicine for enhanced drug delivery
Theranostics. 2020;10(15):6629-6637.
Wang S, Zhang F, Yu G, Wang Z, Jacobson O, Ma Y, Tian R, Deng H, Yang W, Chen ZY, Chen X
840
Dancing with reactive oxygen species generation and elimination in nanotheranostics for disease treatment
Adv Drug Deliv Rev. 2020; 158: 73-90.
Zhou Z, Ni K, Deng H, Chen X
839
Critical reviews of immunotheranostics
Theranostics. 2020;10(16):7403-7405.
Chen X, Chen M.
838
Tuning the properties of atomically precise gold nanoclusters for biolabeling and drug delivery
Chem Commun (Camb). 2020; 56(62): 8766-8769.
Xu MM, Jia TT, Li B, Ma W, Chen X, Zhao X, Zang SQ
837
Engineering macrophages for cancer immunotherapy and drug delivery
Adv Mater, 2020;32(40):e2002054.
Xia Y, Rao L, Yao H, Wang Z, Ning P, Chen X
836
Controllable Synthesis of Versatile Mesoporous Organosilica Nanoparticles as Precision Cancer Theranostics
Biomaterials, 2020;256:120191
Cheng Y, Jiao X, Fan W, Yang Z, Wen Y, Chen X
835
Insight into the Development of PET Radiopharmaceuticals for Oncology
Cancers, 2020;12(5):1312
Lau J, Rousseau E, Kwon D, Lin K-S, Bernard F, Chen X
834
Ultrasmall Copper-Based Nanoparticles for Reactive Oxygen Species Scavenging and Alleviation of Inflammation Related Diseases
Nat Commun, 2020;11(1):2788
Liu T, Xiao B, Xiang F, Tan J, Chen Z, Wu C, Mao Z, Luo G, Chen X, Deng J
833
A single-step multi-level supramolecular system for cancer sonotheranostics
Nanoscale Horiz. 2019;4(1):190-195.
Lin H, Li S, Wang J, Chu C, Zhang Y, Pang X, Lv P, Wang X, Zhao Q, Chen J, Chen H, Liu W, Chen X, Liu G
832
Quantum Dot-Based Sensitization System for Boosted Photon Absorption and Enhanced Second Near-Infrared Luminescence of Lanthanide-Doped Nanoparticle
Anal Chem, 2020; 92(8): 6094-6102.
Zhang W, Chen T, Su L, Ge X, Chen X, Song J, Yang H
831
Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging
Nat Commun, 2020;11(1):3032
Zhou Z, Deng H, Yang W, Wang Z, Lin L, Munasinghe J, Jacobson O, Liu Y, Tang L, Ni Q, Kang F, Liu Y, Niu G, Bai R, Qian C, Song J, Chen X
830
177Lu-EB-PSMA radioligand therapy with escalating doses in patients with metastatic castration-resistant prostate cancer
J Nucl Med, 2020; 61(12):1772-1778.
Zang J, Liu Q, Sui H, Wang R, Jacobson O, Fan X, Zhu Z, Chen X
829
Gadolinium-Rose Bengal Coordinated Polymer Nanodots for MR/Fluorescence ImageGuided Radiation and Photodynamic Therapy
Adv Mater, 2020;32(23):e2000377.
Sun W, Luo L, Feng Y, Qiu Y, Meng S, Chen X, Chen H
828
Biologically Responsive Plasmonic Assemblies for Second Near-Infrared Window Photoacoustic Imaging-Guided Concurrent Chem-Immunotherapy
ACS Nano, 2020; 14(4): 3991-4006.
Zhu R, Su L, Dai J, Li ZW, Bai S, Li Q, Chen X, Song J, Yang H
827
[18F]- Alfatide PET imaging of integrin αvβ3 for the non-invasive quantification of liver fibrosis
J Hepatol. 2020;73(1):161-169.
Shao T, Chen Z, Belov V, Wang X, Rwema SH, Kumar V, Fu H, Deng X, Rong J, Yu Q, Lang L, Lin W, Josephson L, Samir AE, Chen X, Chung RT, Liang SH.
826
Yolk-shell nanovesicles endow glutathione-responsive concurrent drug release and T1 MRI activation for cancer theranostics
Biomaterials, 2020; 244: 119979
Liu D, Zhou Z, Wang X, Deng H, Kang F, Zhang Y, Wang Z, Yang W, Rao L, Yang K, Yu G, Du J, Shen Z, Chen X
825
Stereospecific Interactions between Chiral Nanomaterials and Biological Systems
Chem Soc Rev, 2020; 49: 2481-2503
Zhao X, Zang S, Chen X
824
Solvent-assisted self-assembly of metal-organic framework-based biocatalyst for cascade reactions-driven photodynamic therapy
J Am Chem Soc, 2020; 142(14): 6822-6832.
He L, Ni Q, Mu J, Fan W, Liu L, Wang Z, Li L, Tang W, Liu Y, Cheng Y, Tang L, Yang Z, Liu Y, Zou J, Yang W, Jacobson O, Zhang F, Huang P, Chen X
823
X-ray-Induced Persistent Luminescence Promotes Ultrasensitive Imaging and Effective Inhibition of Orthotopic Hepatic Tumors
Adv Funct Mater, 2020, 2001166
Shi T, Sun W, Qin R, Li D, Feng Y, Chen L, Liu G, Chen X, Chen H
822
Targeting Integrins with Radiolabeled RGD Analogs for Radiotheranostics of Metastatic Radioactive Iodine Non-Responsive Thyroid Cancer - New Avenues in Personalized Medicine
Thyroid. 2020; 30(4): 476-478.
Klubo-Gwiezdzinska J, Chen X.
821
Photoacoustic Imaging-Trackable Magnetic Microswimmers for Pathogenic Bacterial Infection Treatment
ACS Nano, 2020; 14(3): 2880-2893.
Xie L, Pang X, Yan X, Lin H, Ye J, Cheng Y, Dai Q, Zhao Q, Zhang X, Liu G, Chen X
820
Cell Membrane Mimicking Nanodecoys Against Infectious Diseases
ACS Nano, 2020; 14(3): 2569-2574.
Rao L, Tian R, Chen X
819
Conjugation of a Scintillator Complex and Gold Nanorods for Dual-Modal Image-Guided Photothermal and X-RayInduced Photodynamic Therapy of Tumors
ACS Appl Mater Interfaces, 2020; 12(11): 12591-12599.
Luo L, Sun W, Feng Y, Qin R, Zhang J, Ding D, Shi T, Liu X, Chen X, Chen H
818
Endoplasmic Reticulum Targeting to Amplify Immunogenic Cell Death for Cancer Immunotherapy
Nano Lett, 2020; 20(3): 1928-1933.
Deng H, Zhou Z, Yang W, Lin L-S, Wang S, Niu G, Song J, Chen X
817
A Fluorinated-Ionic-Liquid-Based Activatable 19F MRI Platform Enables Detection and Imaging of Biological Targets
Chem, 2020;6:1134-1148.
Zhu X, Tang X, Lin H, Shi S, Xiong H, Zhou Q, Li A, Wang Q, Chen X, Gao J
816
Lymphangioleiomyomatosis revealed by 68Ga-NOTA-Evans Blue PET/CT
Eur J Nucl Med Mol Imaging. 2020; 47(10): 2469-2470.
Hou G, Xu W, Jiang Y, Xu KF, Chen X, Li F, Cheng W
815
Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma
Biomaterials. 2020;235:119783
Shen Z, Liu T, Yang Z, Zhou Z, Tang W, Fan W, Liu Y, Mu J, Li L, Bregadze VI, Mandal SK, Druzina AA, Wei Z, Qiu X, Wu A, Chen X
814
A phototheranostics strategy to continuously deliver singlet oxygen in dark and hypoxic tumor microenvironment
Angew Chem Int Ed Engl. 2020; 59: 1-7.
Zou J, Zhu J, Yang Z, Li L, Fan W, He L, Tang W, Deng L, Mu J, Ma Y, Cheng Y, Huang W, Dong X, Chen X
813
Ultrasound Activated Sensitizers and Applications
Angew Chem Int Ed Engl. 2020; 59: 2-24
Lin X, Song J, Chen X, Yang H.
812
Current clinical status and potential of photothermal and photodynamic cancer therapy
Nat Rev Clin Oncol, 2020; 17(11): 657-674.
Li X, Lovell J, Yoon J, Chen X
811
Burst release of encapsulated annexin A5 in tumours boosts cytotoxic T-cell responses by blocking the phagocytosis of apoptotic cells
Nat Biomed Eng, 2020; 4: 1102-1116.
Li L, Zou J, Dai Y, Fan W, Niu G, Yang Z, Chen X
810
Multiplexed NIR-II imaging for lymph node-invaded cancer detection and full-process light exposure surgery
Adv Mater, 2020;32:1907365
Tian R, Ma H, Zhu S, Lau J, Ma R, Liu Y, Lin L, Chandra S, Wang S, Niu G, Zhang M, Antaris AL, Hettie KS, Yang B, Liang Y, Chen X
809
Oxidative stress-driven DR5 upregulation restores TRAIL/Apo2L sensitivity induced by iron oxide nanoparticles in colorectal cancer
Biomaterials, 2020;233:119753
Shi Y, Wang J, Liu J, Lin G, Xie F, Pang X, Pei Y, Cheng Y, Zhang Y, Lin Z, Yin Z, Wang X, Niu G, Chen X, Liu G
808
Cascaded Multiresponsive Self-Assembled 19F MRI Nanoprobes with Redox-Triggered Activation and NIR-Induced Amplification
Nano Lett, 2020;20(1):363-371
Tang X, Gong X, Li A, Lin H, Peng C, Zhang X, Chen X, Gao J.
807
Combined 68Ga-NOTA-Evans Blue Lymphoscintigraphy and 68Ga-NOTA-RM26 PET/CT Evaluation of Sentinel Lymph Node Metastasis in Breast Cancer Patients
Bioconjug Chem, 2020; 31(2):396-403.
Zang J, Liu Q, Sui H, Guo H, Peng L, Li F, Lang L, Jacobson O, Mao F, Zhu Z, Chen X
806
Smart Nanovesicle Mediated Immunogenic Cell Death Through Tumor Microenvironment Modulation for Effective Photodynamic-Immunotherapy
ACS Nano, 2020;14(1):620-631
Yang W, Zhang F, Deng H, Lin L, Wang S, Kang F, Yu G, Lau J, Tian R, Zhang M, Wang Z, He L, Ma Y, Niu G, Hu S, Chen X
805
Label-free Visualization of Early Cancer Hepatic Micrometastasis and Intraoperative Image-guided Surgery by Photoacoustic Imaging
J Nucl Med. 2020;61(7):1079-1085.
Yu Q, Huang S, Wu Z, Zheng J, Chen X, Nie L.
804
A bi-adjuvant nanovaccine that potentiates immunogenicity of neoantigen for combination immunotherapy of colorectal cancer
Sci Adv, 2020;6:eaaw6071
Ni Q, Zhang F, Liu Y, Wang Z, Yu G, Liang B, Niu G, Su T, Lu G, Zhu G, Zhang L, Chen X
803
Ultrasound Activated Vesicle of Janus Au-MnO Nanoparticles for Promoted Tumor Penetration and Sono-Chemodynamic Therapy of Orthotopic Liver Cancer
Angew Chem Int Ed Engl. 2020;59(4):1682-1688.
Lin X, Liu S, Zhang X, Zhu R, Chen S, Chen X, Song J, Yang H.
802
Nanoscintillator-mediated X-ray induced photodynamic therapy for deep-seated tumors: from concept to biomedical applications
Theranostics, 2020;10(3):1296-1318.
Sun W, Zhou Z, Pratx G, Chen X, Chen H
801
Core–Shell Heterostructured Magnetic–Plasmonic Nanoassemblies with Highly Retained Magnetic–Plasmonic Activities for Ultrasensitive Bioanalysis in Complex Matrix
Adv Sci, 2020;7:1902433
Hao L, Leng Y, Zeng L, Chen X, Chen J, Duan H, Huang X, Xiong Y, Chen X
800
Supramolecular Recognition-Mediated Layer-by-Layer Self-Assembled Gold Nanoparticles for Customized Sensitivity in Paper-Based Strip Nanobiosensors
Small. 2019;15(51):1903861.
Huang X, Zhou Y, Ding L, Yu G, Leng Y, Lai W, Xiong Y, Chen X
799
DOTA-Branched Organic Frameworks as Giant and Potent Metal Chelators
J Am Chem Soc. 2020;142(1):198-206.
Sun C, Lin H, Gong X, Yang Z, Mo Y, Chen X, Gao J.
798
Tale of Two Magnets: A New Design of Magnetic Targeting System
ACS Nano, 2020;14(1):7-11
Zhou Z, Shen Z, Chen X
797
Dose Escalation of an Evans Blue Modified Radiolabeled Somatostatin Analogue 177Lu-DOTA-EBTATE in the Treatment of Metastatic Neuroendocrine Tumors
Eur J Nucl Med Mol Imaging. 2020;47(4):947-957
Liu Q, Cheng Y, Zang J, Sui Hm Wang H, Jacobson O, Zhu Z, Chen X