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Wenxing Gu

Research Fellow

Research interest

Polymeric nanomedicine, Nanovaccine, Drug and mRNA delivery, Cancer immunotherapy

Education background

Liang Zhao_edited_edited.jpg

PhD, University of Twente (Netherlands) & Soochow University (China), 2021

MSc, Pharmaceutical Chemistry, Tianjin University of Technology (China), 2016

BSc, Pharmaceutical Engineering, Tianjin University of Technology, 2013

E-mail:wenxing@nus.edu.sg

Publication

  1. Dandan Wang, Wenxing Gu, Weiliang Chen, Jin Zhou, Le Yu, Byung Kook Kim, Xuenong Zhang, Jong Seung Kim, Advanced nanovaccines based on engineering nanomaterials for accurately enhanced cancer immunotherapy, Coord. Chem. Rev., 2022, 472, 214788

  2. Wenxing Gu, Ruobing Qu, Fenghua Meng, Jeroen J.L.M. Cornelissen, and Zhiyuan Zhong, Polymeric nanomedicines targeting hematological malignancies, J. Control. Release., 2021, 337, 571-588

  3. Wenxing Gu, Fenghua Meng, Rainer Haag and Zhiyuan Zhong, Actively targeted nanomedicines for precision cancer therapy: Concept, construction, challenges and clinical translation, J. Control. Release, 2021, 329, 676-695.

  4. Wenxing Gu, T. Liu, D. Fan, Y.Xia, Fenghua Meng, Y. Xu, Jeroen J. J. L. M. Cornelissen, Z. Liu and Zhiyuan Zhong, A6 peptide-tagged, ultra-small and reduction-sensitive polymersomal vincristine sulfate as a smart and specific treatment for CD44+ acute myeloid leukemia, J. Control. Release, 2021, 329, 706-716.

  5. Wenxing Gu, J. An, H. Meng, N. Yu, Y. Zhong, Fenghua Meng, Y. Xu, Jeroen J.L.M. Cornelissen, and Zhiyuan Zhong. CD44-Specific A6 short peptide boosts targetability and anticancer efficacy of polymersomal epirubicin to orthotopic human multiple myeloma, Adv. Mater., 2019, 1904742.

  6. L. Ding, Wenxing Gu, Y. Zhang, S. Yue, H. Sun, Jeroen J. L. M. Cornelissen, and Zhiyuan Zhong, Biomacromolecules, 2019, 20, 10, 3855.

  7. Wenxing Gu, Q. Li, H. Lu, L.Fang, Q. Chen, Ying-Wei Yang and Hui Gao. Construction of stable polymeric vesicles based on azobenzene and beta-cyclodextrin grafted poly(glycerol methacrylate)s for potential applications in colon-specific drug delivery, Chem. Commun., 2015, 51, 4715.

  8. Wenxing Gu, M. Zhu, N. Song, X. Du, Ying-Wei Yang and Hui Gao. Reverse micelles based on biocompatible β-cyclodextrin conjugated polyethylene glycol block polylactide for protein delivery, J. Mater. Chem. B, 2015, 3, 316.

  9. Wenxing Gu, Ying-Wei Yang, J. Wen, H. Lu and Hui Gao. Construction of reverse vesicles from pseudo-graft poly(glycerol methacrylate)s via cyclodextrin-cholesterol interaction, Polym. Chem., 2014, 5, 6344.

  10. Q. Li, Wenxing Gu, Hui Gao and Ying-Wei Yang. Self-Assembly and applications of poly(glycidyl methacrylate)s and their derivatives, Chem. Commun., 2014, 50, 13201.

  11. Wenxing Gu, Y. Ma, C. Zhu, B. Chen, J. Ma and Hui Gao. Synthesis of cross-linked carboxyl poly(glycerol methacrylate) and its application for the controlled release of doxorubicin, Eur. J. Pharm. Sci., 2012, 47, 556.

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